Academic Leadership Award at the Indiana University School of Medicine

印第安纳大学医学院学术领导奖

• 批准号: 10532250
• 负责人: GARY E. LANDRETH
• 金额: $ 16.19万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10532250
• 关键词: Aging; Alzheimer' s Disease; Alzheimer' s disease model; Alzheimer' s disease related dementia; Animal Model; Award; Basic Science; Caliber; Clinical; Clinical Trials; Collaborations; Communities; Development; Doctor of Medicine; Early Onset Alzheimer Disease; Education; Educational Curriculum; Educational Status; Elements; Employee; Faculty; Funding; Goals; Graduate Education; Home; Human Resources; Indiana; Individual; Institution; Instruction; Investments; Laboratories; Leadership; Medical; Neurodegenerative Disorders; Neurosciences; Neurosciences Research; Postdoctoral Fellow; Principal Investigator; Research; Research Activity; Research Institute; Research Personnel; Resources; Series; Talents; Training; Training Activity; Training Programs; Training Support; Translational Research; Universities; Work; academic program; aged; brain health; cell repository; cognitive function; design; doctoral student; experience; graduate student; medical schools; post-doctoral training; programs; recruit; skills; success; undergraduate research experience

Principal Investigator: Landreth, Gary E Project Summary/Abstract This academic leadership award application is directed at the development of coordinated and comprehensive educational programs in aging, Alzheimer’s disease and related dementias at the Indiana University School of Medicine (IUSM). A primary goal is to provide an organizational framework, anchored in the Medical Neurosciences Training Program, to functionally integrate the activities of existing and developing NIA supported resources at the IUSM. The NIA supports the Indiana Alzheimer’s Disease Research Center, the National Cell Repository for Alzheimer’s Disease, the Regenstrief Institute and the Center for Aging Research as well as the recently funded MODEL-AD center and LEADS clinical trial. Finally, Eli Lilly is headquartered in Indianapolis and has a substantial research effort focused on Alzheimer’s disease. These institutions comprise a unique and significant intellectual and infrastructural resource that will be leveraged in the current proposal. The IUSM and the NIA have recently committed substantial institutional resources to develop basic science research efforts on AD and neurodegenerative diseases. However, the success of the investigative effort will be contingent upon provision of a skilled workforce. The present application describes a plan to employ the Medical Neuroscience Training program as a vehicle to enhance and coordinate the research and training activities at the IUSM. The training program will simultaneously enhance and expand the institutional research capacity by providing a talented pool of young investigators to faculty within the individual research centers, and provide a high level training for these individuals. Importantly, the activities of the training program provide a mechanism to promote interactions and collaborations between the faculty and research staff at IUSM and Lilly who work on aging and neurodegenerative diseases. The applicant, Dr. Gary Landreth, was recruited to IUSM to lead the development and restructuring of the Medical Neurosciences Training Program. He brings to this effort 30 years of experience in Alzheimer’s disease research and graduate education. The Specific Aims of the application are:1) To restructure the Medical Neuroscience Training program through a) modernizing the graduate curriculum to provide foundational training in the Neurosciences, aging and neurodegenerative diseases, b) initiation of a postdoctoral training program to promote the professional advancement of this important component of the scientific workforce and c) provide undergraduate research experiences. 2) To employ the Medical Neuroscience Training Program as a vehicle to integrate the activities of the various IUSM centers focused on Aging and Neurodegenerative diseases. 3) To promote translational research interactions through the Medical Neuroscience Training Program with Eli Lilly.

首席研究员：Landreth，Gary E 项目摘要/摘要 该学术领导奖申请旨在协调的发展和 印第安纳州衰老，阿尔茨海默氏病和相关痴呆症的全面教育计划 大学医学院（IUSM）。一个主要目标是提供一个基于的组织框架 医学神经科学培训计划，在功能上整合现有和开发的活动 NIA支持IUSM的资源。 NIA支持印第安纳州阿尔茨海默氏病研究中心， 阿尔茨海默氏病的国家细胞存储库，雷恩斯特里夫研究所和老龄化中心 研究以及最近资助的Model-AD中心并领导临床试验。最后，礼来公司是 总部位于印第安纳波利斯，并进行了大量研究工作，重点是阿尔茨海默氏病。这些 机构构成了一种独特而重要的知识和基础设施资源，该资源将被利用 当前的建议。 IUSM和NIA最近已投入大量的机构资源来开发基本 科学研究的AD和神经退行性疾病的工作。但是，调查的成功 努力将取决于提供熟练的劳动力。本申请描述了一个计划 员工医学神经科学培训计划是增强和协调研究的工具 在IUSM培训活动。培训计划将简单地增强和扩展机构 通过为个人研究中的教师提供才华横溢的研究人员来研究能力 中心，并为这些人提供高水平的培训。重要的是，培训的活动 计划提供了一种机制来促进教师与研究之间的互动和合作 IUSM和Lilly的工作人员从事衰老和神经退行性疾病。 申请人加里·兰德雷斯（Gary Landreth）博士被招募到IUSM，以领导和重组 医学神经科学培训计划。他在阿尔茨海默氏症中带来了30年的经验 疾病研究和研究生教育。 应用程序的具体目的是：1）限制医学神经科学培训计划 通过a）现代化研究生课程，以提供神经科学的基础培训 和神经退行性疾病，b）促进专业人士的博士后培训计划的主动性 科学劳动力和c）的这一重要组成部分的进步提供了本科研究 经验。 2）使用医学神经科学培训计划作为整合活动的工具 在各种IUSM中心中，集中于衰老和神经退行性疾病。 3）促进翻译 通过与礼来的医学神经科学培训计划进行研究相互作用。