FAIR DOs: Findable, Accessible, Interoperable, Reusable Development of Open Simulation

FAIR DO：可查找、可访问、可互操作、可重用的开放模拟开发

• 批准号: 10523857
• 负责人: Walter F Boron
• 金额: $ 13.04万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10523857
• 关键词: Arts; Autonomic nervous system; Award; Basic Science; Biomedical Engineering; Biophysics; Body Surface; Boron; British; California; Clinic; Computer Models; Data; Data Set; Department chair; Development; Doctor of Philosophy; Ecosystem; Educational process of instructing; Engineering; Ensure; Enteric Nervous System; Epithelial; Epithelial Cells; FAIR principles; Faculty; Feedback; Fostering; Future; Gastrointestinal tract structure; Hour; Information Networks; Infrastructure; Institution; International; Journals; Kidney; Knowledge; Knowledge Management; Leadership; Link; Literature; Maps; Marketing; Master of Science; Medical; Medical Students; Mentors; Methodology; Methods; Modeling; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Nervous System Physiology; Neurobiology; Outcome; Paper; Peer Review; Physiological; Physiological Processes; Physiology; Population; Publications; Publishing; Reproducibility; Research; Research Personnel; Research Project Grants; Resources; Schools; Science; Seasons; Site; Standardization; Structure; Student recruitment; Students; Supervision; Surface; System; Testing; Textbooks; Training; Transport Process; Universities; Validation; Work; base; college; computerized tools; data resource; data sharing; education research; education resources; experience; gastrointestinal; infrastructure development; lectures; mathematical model; medical schools; meter; models and simulation; neuroregulation; next generation; open data; programs; recruit; renal epithelium; response; simulation; Arts; Autonomic nervous system; Award; Basic Science; Biomedical Engineering; Biophysics; Body Surface; Boron; British; California; Clinic; Computer Models; Data; Data Set; Department chair; Development; Doctor of Philosophy; Ecosystem; Educational process of instructing; Engineering; Ensure; Enteric Nervous System; Epithelial; Epithelial Cells; FAIR principles; Faculty; Feedback; Fostering; Future; Gastrointestinal tract structure; Hour; Information Networks; Infrastructure; Institution; International; Journals; Kidney; Knowledge; Knowledge Management; Leadership; Link; Literature; Maps; Marketing; Master of Science; Medical; Medical Students; Mentors; Methodology; Methods; Modeling; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Nervous System Physiology; Neurobiology; Outcome; Paper; Peer Review; Physiological; Physiological Processes; Physiology; Population; Publications; Publishing; Reproducibility; Research; Research Personnel; Research Project Grants; Resources; Schools; Science; Seasons; Site; Standardization; Structure; Student recruitment; Students; Supervision; Surface; System; Testing; Textbooks; Training; Transport Process; Universities; Validation; Work; base; college; computerized tools; data resource; data sharing; education research; education resources; experience; gastrointestinal; infrastructure development; lectures; mathematical model; medical schools; meter; models and simulation; neuroregulation; next generation; open data; programs; recruit; renal epithelium; response; simulation

PROJECT SUMMARY FAIR DOs (Findable, Accessible, Interoperable, Reusable: Development Of Simulations) is a 5-year research education program in the modeling and simulation of digestive and renal neurobiology. It is developed by a team of award-winning faculty of educators and researchers who, among other things, is behind the FAIR mapping and knowledge management infrastructure for the SPARC effort. The main thrust of FAIR DOs is to educate the next generation of researchers and clinicians in the neural regulation of digestive and renal epithelia through taught modules and supervised modeling projects that make use of SPARC datasets, maps, and models. The FAIR DOs faculty will leverage teaching structures at Case Western Reserve University to recruit students. Overall, FAIR DOs aims to provide about 35/45 hours of training to over 75 students over the proposed five-year project, with each student research project producing one publication in the Physiome journal--launched by the International Union of Physiological Sciences. The SPARC Portal will provide findability to these student- generated open-access models and associated data via its Search and Flatmaps functions, as well as accessible interactivity via the O2S2PARC simulation platform. Overall, the FAIR DOs effort will provide a unique educational, mentored experience that will also generate a SPARC ecosystem of interoperating models that coherently study the neurobiology of digestive and renal epithelial transport. From a didactic “Systems” perspective, this ecosystem of models will be organized to follow the teaching narrative of the British Medical Association Award-winning “Medical Physiology 3rd Ed.” textbook, supplemented with recent literature, setting the stage to further leverage SPARC resources for education in the future.

项目摘要 公平DO（可发现，可访问，可互操作，可重复使用：模拟的开发）是一项为期5年的研究 消化和肾脏神经生物学建模和模拟中的教育计划。它是由团队开发的 屡获殊荣的教育工作者和研究人员的教职员工，除其他外 以及用于SPARC工作的知识管理基础架构。公平DOS的主要目的是教育 下一代研究人员和临床医生在神经调节消化和肾上皮的神经调节中 教授使用SPARC数据集，地图和模型的模块和监督建模项目。这 Fair DOS教师将利用Case Western Reserve University的教学结构来招募学生。 总体而言，公平DOS旨在在拟议的五年中为75多名学生提供约35/45小时的培训 项目，每个学生研究项目都在《 Physiome杂志》中生产一个出版物 - 由 国际生理科学联盟。 SPARC门户将为这些学生提供可发现性 - 通过其搜索和Flatmaps功能生成的开放访问模型和相关数据，以及可访问的 通过O2S2PARC仿真平台进行交互性。总体而言，公平的努力将为独特 教育，修改的经验也将产生一个互操作模型的Sparc生态系统 一致研究消化和肾上皮转运的神经生物学。从教学“系统” 观点，这个模型的生态系统将组织起来，以遵循英国医学的教学叙事 协会屡获殊荣的“医学生理学第三版”。教科书，补充了最近的文献，设置 未来将SPARC资源进一步利用教育的阶段。