Gabriella Miller Kids First Pediatric Data Resource Center: Advancing Collaborative Platform-Enabled Data-Driven Discovery at the Intersection of Childhood Development and Cancer

Gabriella Miller Kids First 儿科数据资源中心：在儿童发展和癌症的交叉点推进协作平台支持的数据驱动发现

• 批准号: 10513120
• 负责人: Robert J Carroll
• 金额: $ 400万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-26 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10513120
• 关键词: Address; Advocate; Architecture; Authorization documentation; Biological; Birth; Child; Childhood; Clinical; Communities; Data; Data Commons; Data Science; Data Set; Development; Disease; Distributional Activity; Down Syndrome; Ensure; Environment; Etiology; FAIR principles; Fostering; Funding; Generations; Growth; Hand; Infrastructure; Investigation; Knowledge; Leadership; Link; Longevity; Malignant Childhood Neoplasm; Malignant Neoplasms; Mission; Modality; Outcome; Patients; Pediatric Research; Phase; Phenotype; Research; Research Personnel; Resources; Role; Services; Structural Congenital Anomalies; Testing; Time; Trust; United States National Institutes of Health; Update; Vision; Work; base; clinical decision support; clinical translation; cloud based; cloud platform; cohort; data access; data ecosystem; data resource; data reuse; data sharing; data tools; empowered; empowerment; experience; innovation; interoperability; multidisciplinary; new technology; novel; operation; outreach; programs; software development; success; translational impact

PROJECT SUMMARY Since its launch, the Gabriella Miller Kids First Data Resource Center (KFDRC) has constantly innovated and helped redefine the architecture, development and operations across all cores of work to optimize and provide opportunities for the research community to have impact in childhood cancer and structural birth defects. This has included collaborative partnerships across the NIH data commons landscape to ensure the FAIRness of Kids First data and enable rapid access of data in cloud-based platforms. In the next phase, the KFDRC will build on these innovations and successes to further empower sustained, scaled growth and impact. This will be a cross-coordinated effort across the Administrative and Outreach Core, the Data Coordinating Core and the Data Resource Core. The combined efforts of these cores will provide researchers the data, tools, and workspaces they need to further the mission of the Kids First program. The KFDRC will make significant contributions to accelerate community efforts not only to understand etiology and drivers of pediatric diseases, but also drive and enhance the interpretation and clinical decision support for better outcomes for children.

项目摘要 自推出以来，Gabriella Miller Kids First Data Resource Center（KFDRC）一直在创新和 帮助重新定义了所有工作核心的建筑，开发和运营，以优化和提供 研究界有机会影响儿童癌症和结构性先天缺陷。这 已包括在NIH数据共享环境中的合作伙伴关系，以确保 孩子们的第一个数据，并可以在基于云的平台中快速访问数据。在下一个阶段，KFDRC将 建立在这些创新和成功的基础上，以进一步增强持续的，扩展的增长和影响力。这将是 整个行政和宣传核心，数据协调核心以及 数据资源核心。这些核心的综合努力将为研究人员提供数据，工具和 他们需要进一步的工作区，以进一步迈出孩子们的任务。 KFDRC将变得很重要 加快社区努力的贡献，不仅要了解病因和小儿疾病的驱动因素，还 但是，还可以推动和增强对儿童更好结果的解释和临床决策支持。