Integrated Training For Physician-Scientists

医师科学家综合培训

• 批准号: 10651809
• 负责人: Mark E Burkard
• 金额: $ 104.5万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10651809
• 关键词: Physicians; Scientist; Training

PROJECT SUMMARY/ABSTRACT The Medical Scientist Training Program (MSTP) at the University of Wisconsin-Madison (UW-Madison) aims to train and prepare future leaders and physician-scientists in clinical medicine and biomedical research. Our program trains diverse students across numerous fields, with a curriculum and training plan that is continuously improved through metrics, critical self-assessment, and student input. Guiding principles of our program include: (1) a rigor and caliber of both MD and PhD training equivalent to single-degree candidates; (2) continuous mentoring from program leaders, faculty, and peers; and (3) training in translational research for all students. The four program directors are all physician-scientists and each is active in research, graduate training, and clinical activities. The student government works closely with the directors on recruitment, seminars, advising, curriculum, and continuous improvement. Students begin with the preclinical phase of medical training, along with a 3-semester MSTP-specific Integrated Molecular Medicine (IMM) course series, led by the directors. IMM introduces new trainees to research methodologies, scientific writing, responsible conduct of research (RCR), rigor, reproducibility and transparency (RRT), and implicit bias. Students then proceed through clinical clerkships in the ForWard curriculum before beginning the Ph.D. thesis. Ph.D. mentor selection is made in consultation with program leaders. Oversight of research rigor and Ph.D. mentorship is directly assured by an MSTP director on each thesis committee. An integrated Longitudinal Clinical Experience spans the Ph.D. years. After defending the Ph.D. thesis, trainees enter the final year of medical training, which includes the mentored Clinical & Translational Research Elective (CTRE), custom-designed for MSTP trainees. CTRE is a 6-week preceptorship with both clinical and research facets and an additional physician-scientist faculty mentor. The integrated curriculum allows students to complete dual degree training in 7-8 years, with a minimal gap between intense research activities and postgraduate training. A majority of student theses are in the biological, chemical, population or engineering sciences, yet others select allied programs of study including anthropology, medical history, and clinical investigation, a program integrated with our Clinical Translational Science Award (CTSA). Additional activities foster program cohesiveness and encompass continuous training in RCR, RRT and implicit bias via weekly seminars, our annual retreat and yearly symposium, and regular social gatherings. A diversity committee, jointly led by students and faculty, directs activities for recruitment and retention of exceptional trainees, including a new summer research program for underrepresented undergraduates, which will be implemented in the grant period. RELEVANCE: Trainees receive integrated training in clinical medicine and research and are awarded both M.D. and Ph.D. degrees. Through an innovative integrated physician-scientist curriculum, the diverse graduates of our program are poised for research-intensive careers that integrate rigorous basic and translational research and clinical care.

项目摘要/摘要 威斯康星大学麦迪逊分校（UW-Madison）的医学科学家培训计划（MSTP）的目标是 培训并准备未来的领导者和医师科学家在临床医学和生物医学研究中。我们的 计划通过课程和培训计划培训各个领域的多元学生 通过指标，批判性自我评估和学生意见改进。我们计划的指导原则包括： （1）MD和PHD训练的严格和口径相当于单位候选人； （2）连续 计划领导者，教职员工和同伴的指导； （3）为所有学生的翻译研究培训。 这四位计划主任都是医师科学家，每个人都活跃于研究，研究生培训和 临床活动。学生政府与董事与招聘，研讨会，建议， 课程和持续改进。学生从医学培训的临床前阶段开始 由董事领导的三个学期MSTP特异性综合分子医学（IMM）课程系列。 imm 向研究方法，科学写作，负责任的研究（RCR）介绍了新学员， 严格，可重复性和透明度（RRT）和隐性偏见。然后，学生继续临床文员 在开始博士学位之前，在前进课程中论文。博士导师选择是与 计划负责人。对严格和博士学位的研究监督MSTP主任直接保证 每个论文委员会。综合纵向临床经验跨越博士学位。年。防守后 博士论文，学员进入了医学培训的最后一年，其中包括指导的临床＆ 转化研究选修课（CTRE），针对MSTP受训者进行定制设计。 CTRE是一个为期6周的主持人 具有临床和研究方面，以及其他医师科学家的教师导师。集成 课程允许学生在7 - 8年内完成双学位培训，并且在强烈的差距之间差距很小 研究活动和研究生培训。大多数学生的论点都在生物学，化学中 人口或工程科学，而其他人则选择了盟军的研究计划，包括人类学，医学 历史和临床研究，该计划与我们的临床转化科学奖（CTSA）集成在一起。 其他活动促进了计划的凝聚力，并涵盖了RCR，RRT和隐式的连续培训 通过每周研讨会，我们的年度静修和每年的研讨会以及定期的社交聚会来偏见。多样性 由学生和教职员工共同领导的委员会指导活动以招募和保留卓越 受训人员，包括针对代表性不足的本科生的新夏季研究计划，这将是 在赠款期内实施。相关性：受训者接受临床医学和 研究并获得医学博士学位和博士学位学位。通过创新的综合医师科学家 课程，我们计划的各种毕业生有望为整合的研究密集型职业提供 严格的基本和转化研究和临床护理。

项目成果

Ipsilesional Mu Rhythm Desynchronization Correlates With Improvements in Affected Hand Grip Strength and Functional Connectivity in Sensorimotor Cortices Following BCI-FES Intervention for Upper Extremity in Stroke Survivors.

• DOI: 10.3389/fnhum.2021.725645
• 发表时间: 2021
• 期刊: Frontiers in human neuroscience
• 影响因子: 2.9
• 作者: Remsik AB;Gjini K;Williams L Jr;van Kan PLE;Gloe S;Bjorklund E;Rivera CA;Romero S;Young BM;Nair VA;Caldera KE;Williams JC;Prabhakaran V
• 通讯作者: Prabhakaran V

Comparison of Language and Memory Lateralization by Functional MRI and Wada Test in Epilepsy.

• DOI: pii: 100009
• 发表时间: 2021
• 期刊: Frontiers in neurology and neuroscience research
• 作者: Htet NN;Pizarro R;Nair VA;Chu DY;Meier T;Tunnell E;Rutecki P;Hermann B;Meyerand EM;Prabhakaran V
• 通讯作者: Prabhakaran V

Structural and functional neuroimaging of the effects of the gut microbiome.

• DOI: 10.1007/s00330-021-08486-5
• 发表时间: 2022-06
• 期刊: European radiology
• 影响因子: 5.9

'The Biggest Problem With Access': Provider Reports of the Effects of Wisconsin 2011 Act 217 Medication Abortion Legislation.

“获取的最大问题”：提供者关于威斯康星州 2011 年第 217 号法案药物堕胎立法影响的报告。

• 发表时间: 2023
• 期刊: WMJ : official publication of the State Medical Society of Wisconsin
• 作者: Valley,TarynM;Zander,Meghan;Jacques,Laura;Higgins,JennyA
• 通讯作者: Higgins,JennyA

Dapsone-induced methemoglobinemia and hemolysis in a woman without G6PD deficiency presenting with idiopathic urticaria.

• DOI: 10.1080/16078454.2022.2149943
• 发表时间: 2022-12
• 期刊: HEMATOLOGY
• 影响因子: 1.9
• 作者: Hu, Yang;Geere, Mimansa;Awan, Maham;Leavitt, Andrew D.;Brown, Laura E.;Pearson, Hadley J.;Gandelman, Jocelyn S.;Kogan, Scott C.
• 通讯作者: Kogan, Scott C.