Molecular, Cellular, and Developmental Mechanisms

分子、细胞和发育机制

• 批准号: 10650331
• 负责人: David L. Van Vactor
• 金额: $ 106.11万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10650331
• 关键词: Development; Molecular

Project Summary/Abstract In the 21st century, advances in knowledge, research technologies, and analytical tools have created unprecedented opportunities for major breakthroughs in our understanding of fundamental biological principles and their underlying mechanisms. We propose here a new interdisciplinary program in Molecular, Cellular, and Developmental Mechanisms (MCDM) at Harvard Medical School (HMS) that will build on our recent investments in science infrastructure, education, and training. Our goal is to educate a diverse, rigorous, and independent group of scientists who will identify novel essential questions in mechanistic biology and develop incisive tools for addressing them. Based on our successful predecessor T32 program, we plan to recruit a group of 20 trainees per year beginning in their second year of graduate study from the Biological and Biomedical Sciences umbrella program. These 20 trainees will distribute across a group of 80 MCDM preceptor laboratories. Our approach to cultivating a resilient and creative group of scholars will be both evidence-based and student-centered. We will bring innovative programming to an exceptionally talented pool of trainees. Through continuous improvements in mentorship practice, community engagement and inclusion, we will foster a collaborative community of scholars who are well-prepared to make confident and transformative contributions to life science research and the many research-related careers needed to convert new discoveries about fundamental biological mechanisms into biomedical and life-sciences applications.

项目摘要/摘要 在21世纪，知识，研究技术和分析工具的进步已经创造了 我们对基本生物学原理的理解，实现了重大突破的前所未有的机会 以及它们的基本机制。我们在这里提出了一个新的分子，细胞和细胞跨学科计划 哈佛医学院（HMS）的发展机制（MCDM）将以我们最近的投资为基础 科学基础设施，教育和培训。我们的目标是教育多样，严格和独立的 一群科学家将确定机械生物学的新基本问题并开发敏锐的工具 解决他们。根据我们成功的前身T32计划，我们计划招募一组20名受训者 每年从生物学和生物医学的研究生研究的第二年开始 程序。这20名学员将分发在80个MCDM主管实验室的组中。我们的方法 培养有弹性和创造力的学者小组将以循证为基础和以学生为中心。我们将 将创新的编程带到一个非常有才华的学员池中。通过持续的改进 在指导实践，社区参与和包容中，我们将建立一个合作社区 精心准备的学者为生活科学研究做出自信和变革的贡献 转换有关基本生物学机制的新发现所需的许多与研究有关的职业 进入生物医学和生命科学应用。