Gulf Coast Center for Precision Environmental Health
墨西哥湾沿岸精准环境健康中心
基本信息
- 批准号:10647883
- 负责人:
- 金额:$ 157.2万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-05-15 至 2025-03-31
- 项目状态:未结题
- 来源:
- 关键词:AccelerationAreaAutomobile DrivingAwarenessBackBiological Specimen BanksChemicalsCommunicationCommunitiesCore FacilityCountryData ScienceDevelopmentDisastersDisciplineDiseaseEducational workshopEmergency SituationEmerging TechnologiesEnvironmentEnvironmental HealthEnvironmental ScienceEpigenetic ProcessFacultyFeesFloodsFosteringFundingGasesGeneticGoalsGrantHealthHealth PolicyHealth SciencesHealth Services AccessibilityHomeHumanHurricaneIndividualIndustryInfrastructureInstitutionInstitutional Review BoardsInterventionInvestigationLeadershipLifeLinkMedical centerMentorsNational Institute of Environmental Health SciencesOilsPilot ProjectsPlantsPlayPolicy MakingPopulationProtocols documentationQuestionnairesResearchResearch ActivityResearch PersonnelResourcesRoleSeasonsServicesStructureTechnologyTexasTrainingTraining ProgramsTranslatingTranslational ResearchTranslationsVisionbasecareer developmentcatalystcommunity engagementdisorder riskempowermentexperiencegulf coasthealth science researchhigh riskimprovedinstrumentationinter-institutionalman-made disastersmembermultidisciplinarynext generationpreferenceprogramsresearch and developmentresponseskillssuperfund site
项目摘要
ABSTRACT: OVERALL
The Houston-Galveston area is home to over a dozen Superfund sites, and is a hub for the petrochemical
industry with 500 chemical plants, 10 refineries and >6000 miles of oil, gas and chemical pipelines in what has
become the country’s largest energy corridor. The area is also home to the largest medical center in the world,
the Texas Medical Center. Thus, both the need, and size of the opportunity, for an NIEHS Environmental Health
Sciences (EHS) Core Center (EHS-CC) in this region is great. As the EHS-CC for the Texas Medical Center,
the Gulf Coast Center for Precision Environmental Health (GC-CPEH) will be the focal point and catalyst for
impactful EHS research, multi-directional communication with local communities and stakeholders, and the
engine driving translation of precision environmental health research advances to improve human health. The
Goals for the GC-CPEH are to 1: Integrate and catalyze impactful EHS research across disciplines and
institutions of the Texas Medical Center, and promote the next-generation of EHS researchers; 2: Provide inter-
institutional access to resources and cutting-edge technologies to accelerate translation, and reverse
translation, of research advances to improve human environmental health; 3: Support and empower
community engagement across the Gulf Coast region by linking community stakeholders and investigators in
multi-directional communication activities that inform GC-CPEH research; 4: Enable rapid response research
activities during and after environmental disasters in the Gulf Coast region. The GC-CPEH has 34 Full
members, 17 of whom have active NIEHS-funded grant support with an annual direct funding base >$5 million.
The Center will support precision environmental health research through its Thematic Focus Areas: Early Life
Genetic and Epigenetic Environment Interactions; Mechanisms and Interventions in Human Environmental
Disease; and Disaster Research Response. The GC-CPEH will also promote research through its Pilot Project
Program, accelerate research advances with seamless access to Next-gen technologies via the PIPELINE
Facility Core and an IHSFC that will promote translational research; activities facilitated by Navigators and the
Matching Funds Core Utilization Program. The Administrative Core, composed of highly seasoned EHS
leaders, provides organizational infrastructure, and mentoring for junior faculty that includes a Career
Development Leaders-in-Training program to promote development of research and professional leadership
skills. An experienced and vibrant CEC will foster multi-directional communication with communities and
stakeholders, and inform environmental health policy for the Gulf Coast Region.
摘要:总体
休斯顿 - 加尔维斯顿地区拥有十多个超级基金的家园,是石化的枢纽
具有500种化工厂,10个炼油厂和> 6000英里的油,天然气和化学管道的行业
成为该国最大的能源库里奇。
因此,得克萨斯州医疗中心。
科学(EHS)核心中心(EHS-CC)在德克萨斯医学中心的EHS-CC中
墨西哥湾沿岸Precisis环境健康中心(GC-CPEH)将成为焦点和催化剂
Impactoful EHS研究,与当地社区和利益相关者的多向沟通以及您
驾驶精确健康研究的转化可以改善人类健康
GC-CPEH的目标为1:整合并促进跨学科的影响EHS研究
德克萨斯州医疗中心的工厂,并促进EHS研究人员的下一代;
将资源和尖端技术的启用,以加速翻译和逆转
翻译,改善人类环境健康的研究; 3:支持和授权
通过将社区利益相关者和调查人员联系起来,整个墨西哥湾沿岸地区的社区英语
多个方向的交流活动,为GC-CPEH研究提供了信息;
墨西哥湾沿岸地区的环境灾难期间的活动。
成员,其中17名积极的NIEHS资助了赠款支持,直接资助基础> 500万美元。
该中心将支持精确的环境健康研究Thematich Thematich焦点领域:早期生活
遗传和表观遗传环境相互作用;
疾病和灾难研究。
程序,通过管道加速研究,并通过无缝到下一代技术进行进步
设施核心和IHSFC IHSFC将促进导航员和您的活动;
匹配资金核心利用计划。
领导者,提供组织基础设施和为初级教师提供指导,包括职业
培训计划的发展领导者旨在促进研究和专业领导的发展
技能。
利益相关者,并为墨西哥湾沿岸地区的环境卫生提供信息。
项目成果
期刊论文数量(173)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Sex-specific epigenetic development in the mouse hypothalamic arcuate nucleus pinpoints human genomic regions associated with body mass index.
- DOI:10.1126/sciadv.abo3991
- 发表时间:2022-09-30
- 期刊:
- 影响因子:13.6
- 作者:
- 通讯作者:
CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression.
- DOI:10.1136/jmedgenet-2020-106987
- 发表时间:2021-07
- 期刊:
- 影响因子:4
- 作者:Cao X;Wolf A;Kim SE;Cabrera RM;Wlodarczyk BJ;Zhu H;Parker M;Lin Y;Steele JW;Han X;Ramaekers VT;Steinfeld R;Finnell RH;Lei Y
- 通讯作者:Lei Y
ROLE OF CYTOCHROME P450S IN THE GENERATION AND METABOLISM OF REACTIVE OXYGEN SPECIES.
- DOI:10.1016/j.cotox.2017.10.003
- 发表时间:2018-03
- 期刊:
- 影响因子:4.6
- 作者:Veith A;Moorthy B
- 通讯作者:Moorthy B
Multiomic Investigations into Lung Health and Disease.
- DOI:10.3390/microorganisms11082116
- 发表时间:2023-08-19
- 期刊:
- 影响因子:4.5
- 作者:
- 通讯作者:
Under-recognition of medically unexplained symptom conditions among US Veterans with Gulf War Illness.
- DOI:10.1371/journal.pone.0259341
- 发表时间:2021
- 期刊:
- 影响因子:3.7
- 作者:Kane NS;Anastasides N;Litke DR;Helmer DA;Hunt SC;Quigley KS;Pigeon WR;McAndrew LM
- 通讯作者:McAndrew LM
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Cornelis Johan Elferink其他文献
Cornelis Johan Elferink的其他文献
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{{ truncateString('Cornelis Johan Elferink', 18)}}的其他基金
Hepatic Aryl Hydrocarbon Receptor Regulation of Obesity: Mechanisms of Action
肝芳基烃受体对肥胖的调节:作用机制
- 批准号:
10701901 - 财政年份:2022
- 资助金额:
$ 157.2万 - 项目类别:
Administrative Supplement for Gulf Coast Center for Precision Environmental Health
墨西哥湾沿岸精准环境健康中心行政补充
- 批准号:
10436634 - 财政年份:2019
- 资助金额:
$ 157.2万 - 项目类别:
Gulf Coast Center for Precision Environmental Health
墨西哥湾沿岸精准环境健康中心
- 批准号:
10390320 - 财政年份:2019
- 资助金额:
$ 157.2万 - 项目类别:
Aryl Hydrocarbon Receptor-Mediated Epigenetic Processes
芳基烃受体介导的表观遗传过程
- 批准号:
9124375 - 财政年份:2016
- 资助金额:
$ 157.2万 - 项目类别:
A Novel Paradigm for Aryl Hydrocarbon Receptor Signaling
芳基烃受体信号传导的新范例
- 批准号:
8896257 - 财政年份:2015
- 资助金额:
$ 157.2万 - 项目类别:
Gulf Coast Health Alliance: health Risks related to the Macondo Spill (GC-HARMS)
墨西哥湾沿岸健康联盟:与马孔多泄漏事件相关的健康风险 (GC-HARMS)
- 批准号:
8469037 - 财政年份:2011
- 资助金额:
$ 157.2万 - 项目类别:
Gulf Coast Health Alliance: health Risks related to the Macondo Spill (GC-HARMS)
墨西哥湾沿岸健康联盟:与马孔多泄漏事件相关的健康风险 (GC-HARMS)
- 批准号:
8727814 - 财政年份:2011
- 资助金额:
$ 157.2万 - 项目类别:
Gulf Coast Health Alliance: health Risks related to the Macondo Spill (GC-HARMS)
墨西哥湾沿岸健康联盟:与马孔多泄漏事件相关的健康风险 (GC-HARMS)
- 批准号:
8213830 - 财政年份:2011
- 资助金额:
$ 157.2万 - 项目类别:
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