Postdoctoral Training in Translational Neurorehabilitation Research

转化神经康复研究博士后培训

• 批准号: 8858656
• 负责人: JOHN WHYTE
• 金额: $ 10.82万
• 依托单位: ALBERT EINSTEIN HEALTHCARE NETWORK
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-13 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8858656
• 关键词: Neurorehabilitation; Research; post-doctoral training

DESCRIPTION (provided by applicant): Advances in basic sciences related to cognition, motor control, and neuroplasticity offer exciting opportunities for treatment advances in neurorehabilitation. Maturation of promising discoveries to validated treatments faces the translational research challenges familiar to all biomedical domains, while also encountering some rehabilitation-specific obstacles. Research collaborators from Moss Rehabilitation Research Institute and Behavioral Neurology and the Center for Functional Neuroimaging at the University of Pennsylvania join forces to offer a post-doctoral research training program in Translational Neurorehabilitation Research, built on the platform of more than 10 years of multidisciplinary collaboration. The program will train 3-4 postdoctoral fellows at a time, recruitd from basic science and clinical disciplines, using a mixture of didactic and hands-on training methods. Program faculty collectively have expertise in 5 key themes that are critical to maturation of treatments from initial concept to validated treatment, including: Theories of normal and abnormal processing; Impairment assessment; Naturalistic assessment; Modulation of neuronal plasticity and learning mechanisms; and Theory-driven treatment trials, and are experienced in a range of cutting edge research tools, including structural and functional neuroimaging, eye- and motion-tracking, computational modeling, virtual reality, psychopharmacology, transcranial magnetic stimulation and transcranial direct current stimulation. Moreover, several individual faculty and collaborative groups have demonstrated expertise in advancing assessments and treatments toward clinical implementation. Thus, trainees have the ability to learn specific tools and perspectives that are applicable to neurorehabilitation research, while benefiting from mentored exposure to the process of translating scientific advances into clinically useful assessments and treatments.

描述（由申请人提供）：与认知、运动控制和神经可塑性相关的基础科学的进步为神经康复治疗的进步提供了令人兴奋的机会。有前景的发现到经过验证的治疗方法的成熟面临着所有生物医学领域都熟悉的转化研究挑战，同时也遇到了一些康复特定的障碍。来自莫斯康复研究所和行为神经病学以及宾夕法尼亚大学功能神经影像中心的研究合作者联手提供转化神经康复研究的博士后研究培训项目，该项目建立在十多年的多学科合作平台上。该项目将同时培训 3-4 名博士后研究员，他们从基础科学和临床学科中招募，采用教学和实践相结合的培训方法。项目教师共同拥有 5 个关键主题的专业知识，这些主题对于从最初概念到验证治疗的成熟治疗至关重要，包括： 正常和异常处理的理论；减值评估；自然主义评估；神经元可塑性和学习机制的调节；和理论驱动的治疗试验，并且在一系列尖端研究工具方面拥有丰富的经验，包括结构和功能神经影像、眼睛和运动跟踪、计算建模、虚拟现实、精神药理学、经颅磁刺激和经颅直流电刺激。此外，一些个别教师和合作小组在推进评估和治疗走向临床实施方面表现出了专业知识。因此，学员有能力学习适用于神经康复研究的特定工具和观点，同时受益于将科学进步转化为临床有用的评估和治疗的过程的指导。