Integrated Training in Engineering and Diabetes

工程和糖尿病综合培训

• 批准号: 10452921
• 负责人: Jamey D. Young
• 金额: $ 4.95万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10452921
• 关键词: Diabetes Mellitus; Engineering; Training

PROJECT SUMMARY/ABSTRACT Diabetes is a complex disease with multiple risk factors/causes, and a broad spectrum of complications. The rational development of novel clinical treatments for diabetes will require interdisciplinary approaches to integrate multiple data sources, build predictive models, and develop new technologies that will together reveal the multifactorial underpinnings of the disease. Such approaches are well-developed in engineering, but they have not been widely applied to diabetes, in part because of a lack of people skilled in both engineering and biomedical research. To develop such an interdisciplinary workforce, we propose to continue a novel Integrated Training in Engineering and Diabetes (ITED) program to attract both predoctoral students and postdoctoral fellows with engineering and quantitative physical science backgrounds to work on research problems at the interface of engineering and diabetes. Vanderbilt University is an ideal location for this program because of the close integration and proximity of the Schools of Engineering and Medicine, the outstanding environment for diabetes research, and the long-standing tradition of collegiality and collaboration across the Vanderbilt campus. The overall goal of the program is to provide talented individuals from engineering backgrounds with state-of-the-art training in diabetes research, which will give them a broad perspective of both basic biomedical research and associated clinical challenges. Forty-one faculty preceptors, equally distributed between those with an engineering background and a diabetes research focus, will work together to offer a wide variety of research opportunities in engineering and diabetes research. Our program includes: a) a novel dual mentor plan where each trainee performs interdisciplinary research in two labs, b) an efficient didactic program that provides trainees with the necessary knowledge base in a compact time-frame that promotes timely completion of their degree, and c) interactions with other trainees, faculty, and visiting scientists. Two experienced mentors, one from engineering and one from a diabetes research background, will supervise each trainee. This interdisciplinary approach requires the trainees to spend significant time in each of the mentors’ labs. A broad educational program for predoctoral trainees will leverage existing courses in the Schools of Engineering and Medicine, supplemented by research seminars, a monthly Data Club, and an annual ITED Retreat. Postdoctoral trainees with engineering degrees will be specifically recruited to this program, and will participate in all ITED activities. We do not expect the postdoctoral trainees to have a background in diabetes research, so they will achieve competency through didactic instruction. Support for 4 predoctoral trainees and 2 postdoctoral trainees is requested based on the research resources of the faculty preceptors. A Steering Committee that represents the breadth of participating investigators will select trainees based on their academic and research performance, and their promise as independent investigators. The program will provide RCR training and actively seek to support disabled individuals and those from minority groups.

项目摘要/摘要 糖尿病是一种复杂的疾病，具有多种危险因素/原因，并且是广泛的并发症。这 新型糖尿病临床治疗的合理发展将需要跨学科的方法来整合 多个数据源，建立预测模型并开发新技术，这些技术将共同揭示 该疾病的多因素基础。这种方法在工程方面已经发达了，但是 没有被广泛应用于糖尿病，部分原因是缺乏工程和生物医学的人 研究。为了发展这样的跨学科劳动力，我们建议继续进行新颖的综合培训 工程和糖尿病（ITED）计划，以吸引前学生和博士后研究员 工程和定量物理科学背景，以解决研究问题的界面 工程和糖尿病。范德比尔特大学（Vanderbilt University）是该计划的理想场所 工程和医学流派的整合和邻近，糖尿病的杰出环境 研究，以及整个范德比尔特校园的合作与合作的悠久传统。 该计划的总体目标是为来自工程背景的才华横溢的人提供最先进的个人 糖尿病研究的培训，这将使他们对基本生物医学研究和 相关的临床挑战。四十一个教师主持人，同样分布在有 工程背景和糖尿病研究重点将共同努力，提供各种各样的研究 工程和糖尿病研究的机会。我们的计划包括：a）一个新颖的双重心理计划 每个学员在两个实验室中进行跨学科研究，b）一个有效的教学计划，提供 具有必要的知识基础的学员，以紧凑的时间框架促进及时完成 学位以及c）与其他学员，教职员工和来访科学家的互动。两个经验丰富的导师，一个 从工程和糖尿病研究背景的工程中，将监督每个学员。这 跨学科的方法要求学员在每个导师的实验室中花费大量时间。广泛 对学年学员的教育计划将利用工程学学校的现有课程 医学，由研究中心，每月的数据俱乐部和年度静修会补充。博士后 具有工程学位的学员将专门招募该计划，并将参加所有IT 活动。我们不希望博士后学员在糖尿病研究中具有背景，因此他们会 通过教学教学实现能力。支持4位学员和2名博士后学员 根据教职员工的研究资源要求。指导委员会代表 参与调查人员的广度将根据学术和研究表现选择受训者 以及他们作为独立调查员的承诺。该计划将提供RCR培训，并积极寻求 支持残疾人和来自少数群体的人。