Efficiency of Various Devices and Theories to Collect Nanoparticles Directly onto

直接收集纳米颗粒的各种设备和理论的效率

• 批准号: 9282836
• 负责人: Candace SuJung Tsai
• 金额: $ 6.48万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-02 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9282836
• 关键词: Efficiency; Various; Devices; Theories; Collect

DESCRIPTION (provided by applicant): Transmission electron microscope (TEM) is a very useful technique for evaluating nanoparticle morphology, for elemental analysis, and for particle counting and sizing. This technique has recently become a required tool to characterize exposure to airborne nanoparticles. The specific aim of this proposed research is to compare the available methods using TEM diffusive sampler (TDS), electrostatic precipitation sampler (EPS) and thermophoretic sampler (TPS) for directly depositing airborne engineered nanoparticles (ENPs) onto grids for material characterization. Research objectives include: comparison of size distributions, deposition uniformity and the ease of use. Test nanoparticle aerosols will be generated and samples will be collected side-by-side with three devices using each method, along with the NanoScan SMPS (TSI Model 3910, 10-420 nm) and Optical Particle Counter (OPC) (TSI Model 3330, 300 nm- 10 �m) to record the particle concentration. Experiments will be performed in the Birck Nanotechnology cleanroom laboratory at Purdue University. This research will test the following hypotheses: (1) Basic aerosol theory can be used to predict particle collection onto TEM grids; (2)TPS is more efficient than TDS and EPS for collecting particles less than 200 nm directly onto a TEM grid, EPS is more efficient than TPS and TDS for collecting particles from 200 nm - 10 �m, and none of the techniques are efficient at collecting particles larger than 1 �m; and (3) Nanoparticles collected by all three mechanisms are randomly distributed across a grid surface. The results from this research will provide informative technical results to develop the adequate use of samplers for collecting nanoparticles. In addition, the results will provide the input for further modifications to existin samplers or the development of a newly-designed sampler which can provide better performance for future research.

描述（由申请人提供）：透射电子显微镜（TEM）是一种非常有用的技术，用于评估纳米颗粒形态、元素分析以及颗粒计数和尺寸测定，该技术最近已成为表征空气中特定纳米颗粒暴露的必要工具。本研究的目的是比较使用 TEM 扩散采样器 (TDS)、静电沉淀采样器 (EPS) 和热泳采样器 (TPS) 直接沉积机载工程材料的可用方法研究目标包括：比较尺寸分布、沉积均匀性和易用性，并使用每种方法使用三个设备并排收集样品。以及 NanoScan SMPS（TSI 型号 3910，10-420 nm）和光学粒子计数器 (OPC)（TSI 型号 3330，300 nm- 10 µm) 来记录颗粒浓度。这项研究将在普渡大学的 Birck 纳米技术洁净室实验室中进行，以测试以下假设：(1) 基本气溶胶理论可用于预测 TEM 网格上的颗粒收集； )TPS 比 TDS 和 TDS 更能将小于 200 nm 的有效粒子直接收集到 TEM 网格上，EPS 比 TPS 和 TDS 更有效地收集 200 nm - 10 的有效粒子 �m，并且没有一种技术能够有效地收集大于 1�m 的颗粒；(3) 所有三种机制收集的纳米颗粒都是随机分布在网格表面上的。此外，研究结果将为进一步修改现有采样器或开发新设计的采样器提供输入，从而为未来的研究提供更好的性能。