Trusted Messengers: Supporting Physicians in Promoting COVID-19 Vaccination

值得信赖的使者：支持医生推广 COVID-19 疫苗接种

基本信息

批准号：
10406381
负责人：
Kimberly Fisher
金额：
$ 72.9万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-05-17 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10406381
关键词：
2019-nCoV Address Black race COVID-19 COVID-19 booster COVID-19 impact COVID-19 pandemic COVID-19 risk COVID-19 vaccination COVID-19 vaccine Cessation of life Clinic Clinical Communities Development Disease Educational Materials Effectiveness of Interventions Environment Ethnic Origin Evaluation Federally Qualified Health Center Goals Hand Health Healthcare Systems Herd Immunity Influentials Influenza Information Dissemination Interdisciplinary Study Intervention Latino Libraries Life Patients Persons Physician&apos s Role Physicians Population Populations at Risk Positioning Attribute Pragmatic clinical trial Primary Health Care Race Randomized Clinical Trials Reach Effectiveness Adoption Implementation and Maintenance Recommendation Research Resources Role Source Surveys System Testing Text Messaging Trust United States Vaccinated Vaccination Vaccines Vulnerable Populations Work care providers clinical research site community organizations community partnership ethnic minority population evidence base health disparity implementation science multi-component intervention outreach patient-clinician communication primary outcome racial minority population socioeconomic disadvantage tool unvaccinated uptake vaccine acceptance vaccine hesitancy

项目摘要

PROJECT SUMMARY/ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and associated coronavirus disease 2019 (COVID-19) pandemic have been devastating. In the United States (US), more than 25 million people have been infected, resulting in more than 430,000 deaths. Black and Latino communities have borne a starkly disproportionate impact of COVID-19, compounding existing health disparities. The approval of multiple effective COVID-19 vaccines has raised hope that a return to “normal” life may be at hand, but realizing the full benefits of vaccines will require widespread acceptance and uptake. Our work and that of others indicate a significant proportion of the US population are reluctant to be vaccinated. Overlap between factors associated with COVID-19 disease and COVID-19 vaccine hesitancy, including being of Black or Latino race/ethnicity, and socioeconomic disadvantage, threaten to severely exacerbate existing health disparities. The overarching goal of this proposal is to overcome COVID-19 vaccine hesitancy, particularly among vulnerable populations. Building on strong existing community partnerships, we will refine, implement, and evaluate a multi-faceted intervention to support primary care providers and community organizations as trusted messengers to promote COVID-19 vaccination among vulnerable patients in and near Worcester, MA. Our intervention will include: (1) an online library of videos addressing common vaccine concerns to be disseminated by PCPs and local community organizations; (2) evidence-based text messaging from PCPs to their patients conveying recommendations for and information about COVID-19 vaccination; and (3) concise educational materials for PCPs to support their conversations with patients about the COVID-19 vaccine. We will implement and evaluate the intervention via a large pragmatic clinical trial at two Federally Qualified Health Centers, and the UMass Memorial Health Center. These three clinical systems collectively serve large populations of racial and/or ethnic minority groups (Black, Latino, non-primary English speakers) and socioeconomically disadvantaged patients. Our specific aims are: (1) To refine and adapt tools to support effective PCP recommendations for COVID-19 vaccination and information dissemination by PCPs and community organizations to vulnerable patients; (2) To implement and assess the impact of the intervention on COVID-19 vaccine uptake among initially unvaccinated patients and (3) To evaluate the intervention according to the RE- AIM framework, incorporating the perspectives of patients, primary care providers, and clinic leaders. We will characterize the local community environment before, during and beyond the intervention period and will identify ways the environment supports or inhibits intervention effectiveness. This research will generate crucial evidence of how to effectively promote COVID-19 vaccination among vulnerable populations. Our findings can be applied to promote uptake of other vaccines (including possible COVID-19 vaccine “boosters”) among populations at risk of vaccine hesitancy and health disparities.

项目摘要/摘要严重的急性呼吸综合征冠状病毒2（SARS-COV-2）和相关冠状病毒病 2019年（Covid-19）大流行一直是毁灭性的。在美国（美国），超过2500万人已被感染，导致430,000多人死亡。黑人和拉丁裔社区已经证明了 Covid-19对现有的健康差异的影响严重不成比例。多个批准有效的Covid-19疫苗已经提出了希望重返“正常”生活的希望，但意识到疫苗的好处将需要接受宽度和吸收。我们的工作和其他工作表明美国大部分人口不愿接种疫苗。相关因素之间的重叠与COVID-19疾病和Covid-19疫苗犹豫不决，包括黑人或拉丁裔种族/种族，以及社会经济灾难有可能严重加剧现有的健康差异。总体目标该提议的内容是克服1900疫苗犹豫，尤其是在脆弱人群中。在强大的现有社区合作伙伴关系的基础上，我们将完善，实施和评估一个多方面的干预以支持初级保健提供者和社区组织作为可信赖的使者马萨诸塞州伍斯特及其附近脆弱患者的COVID-19。我们的干预将包括：（1）一个在线视频库，涉及PCP和本地传播的常见疫苗问题社区组织；（2）从PCP到患者输送的循证文本消息传递有关COVID-19的建议和信息的建议；（3）简洁的教育材料 PCP支持他们与患者有关COVID-19疫苗的对话。我们将实施并通过在两个联邦资格的健康中心进行的大型务实临床试验评估干预措施， UMass Memorial Health Center。这三个临床系统共同为大量的种族服务和/或少数民族群体（黑人，拉丁裔，非主要英语说话者）和社会经济不利的患者。我们的具体目的是：（1）完善和调整工具以支持有效的PCP PCP和社区的COVID-19疫苗接种和信息传播的建议组织对弱势患者的组织；（2）实施和评估干预对COVID-19的影响最初未接种疫苗的患者的疫苗摄取，（3）根据重新评估干预措施 AIM框架，结合了患者，初级保健提供者和诊所领导者的观点。我们将在干预期之前，期间和之后都要表征当地社区环境的特征确定环境支持或抑制干预效力的方式。这项研究将产生关于如何有效促进脆弱人群中的共同疫苗接种的关键证据。我们的可以应用发现以促进其他疫苗的摄取（包括可能的COVID-19疫苗“助推器”）在有疫苗犹豫和健康差异风险的人群中。