Effects of Attachment-Based Intervention on Low-Income Latinx Infants' and Mothers' Cardiac Vagal Regulation

基于依恋的干预对低收入拉丁裔婴儿和母亲心脏迷走神经调节的影响

• 批准号: 10378677
• 负责人: LISA J BERLIN
• 金额: $ 7.73万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10378677
• 关键词: Acculturation; Affect; Behavioral; Berlin; Biological; Breathing; Cardiac; Child; Child Health; Cohort Effect; Communities; Community Networks; Data Analyses; Data Collection; Development; Environment; Evaluation; Family; Foundations; Foxes; Funding; Health; Hydrocortisone; Infant; Intervention; Investigation; Latinx; Link; Literature; Low income; Mediating; Modeling; Mothers; Neighborhoods; Outcome; Pathway interactions; Phase; Play; Population; Psychophysiology; Regulation; Research; Resources; Rest; Risk; Role; Sampling; Secure; Security; Series; Sinus Arrhythmia; Skin; Stress; Testing; Underrepresented Populations; Variant; base; biobehavior; care giving burden; caregiving; experience; experimental study; high risk; high risk infant; improved; indexing; intervention effect; maternal caregiving; maternal stress; physical conditioning; programs; public health relevance; respiratory; response; social cohesion; social culture; stressor

According to the biological embedding model, early environments get “under the skin” via stress regulation to influence physical health. Consistent with this model, attachment research links supportive caregiving to health outcomes, but underlying psychophysiological mechanisms are not well understood. This R03 proposal focuses on cardiac vagal tone, an important index of stress regulation that has been associated with early caregiving and physical health. In particular, we will examine infants' and mothers' respiratory sinus arrhythmia (RSA) at rest and in response to mild stressors. We hypothesize that attachment-based interventions that promote sensitive caregiving and infants' and mothers' stress regulation have the potential to support good physical health. The extant literature suggests that mothers' sensitive caregiving may influence infant RSA, maternal RSA, and RSA synchrony, but causal effects have not been tested. These effects require rigorous investigation to elucidate the developmental pathways to effective stress regulation. Results will in turn inform improvement and evaluation of attachment-based interventions and their effects on child health. Thus, experimental studies of attachment- based interventions are necessary to test whether and how caregiving causally affects the development of RSA, and for whom such interventions are most effective. The proposed study will extend PI Berlin's recently completed RCT testing the Attachment and Biobehavioral Catch-up (ABC) program with low-income, Latinx mothers and their infants (N = 181). RCT findings to date illustrate positive effects on maternal sensitivity and infant behavioral and cortisol regulation. In a supplemental data collection, electrocardiographic recordings, from which RSA scores can be constructed, were collected from both infants and mothers during a series of mild stressors. Supplemental funding is required to (a) clean, edit, and calculate RSA values; and (b) conduct data analysis. The sample reflects an underrepresented and potentially highly informative population in which to study the associations among caregiving and stress regulation, as sociocultural context may play an especially important role in stress regulation for Latinx families. Therefore, increased maternal sensitivity may be more important – and attachment-based intervention more effective - for Latinx families characterized by higher-risk (lower-resourced) sociocultural contexts. We will test ABC intervention effects on infant RSA, maternal RSA, and infant-mother RSA synchrony (Aim 1). We will also test two aspects of sociocultural context (maternal acculturation and neighborhood social cohesion) as moderators of intervention effects (Aim 2). By leveraging an existing RCT involving an underrepresented population potential impact will be high: This study will break new ground and will create, through the generation of effect sizes and statistical power estimations, a foundation for the next phase of this research: a more comprehensive (R01) study of the potential of attachment-based intervention to improve children's health outcomes in low-income Latinx families.

根据生物嵌入模型，早期环境通过压力调节进入“皮下” 与此模型一致，依恋研究将支持性护理与健康联系起来。 的结果，但潜在的心理生理机制尚未得到很好的理解。 心脏迷走神经张力是压力调节的重要指标，与早期护理和护理有关 特别是，我们将检查婴儿和母亲在休息和休息时的呼吸性窦性心律失常（RSA）。 我们捕捉到了促进敏感的基于依恋的干预措施。 护理以及婴儿和母亲的压力调节有可能支持良好的身体健康。 现有文献表明，母亲的敏感护理可能会影响婴儿 RSA、母亲 RSA 和 RSA 同步性，但因果效应尚未经过测试，这些效应需要严格的调查来阐明。 有效压力调节的发展途径将反过来为改善和评估提供信息。 基于依恋的干预措施及其对儿童健康的影响因此，依恋的实验研究。 有必要采取基于干预措施来测试护理是否以及如何对发育产生因果影响 RSA 的研究人员，以及此类干预措施对谁最有效。拟议的研究将扩展 PI Berlin 的研究。 最近完成的随机对照试验（RCT）测试了低收入群体的依恋和生物行为追赶（ABC）计划， 拉丁裔母亲及其婴儿（N = 181）迄今为止的随机对照试验结果表明对母亲敏感性的积极影响。 以及婴儿行为和皮质醇调节在补充数据收集、心电图记录中， RSA 评分是在一系列轻度症状期间从婴儿和母亲那里收集的 需要补充资金来 (a) 清理、编辑和计算 RSA 值；以及 (b) 处理数据。 该样本反映了一个代表性不足且可能信息丰富的研究人群。 照顾和压力调节之间的关联，因为社会文化背景可能发挥特别重要的作用 对于拉丁裔家庭的压力调节发挥着重要作用，因此，母亲敏感性的增加可能更为重要。 对于以高风险为特征的拉丁裔家庭来说很重要，而且基于依恋的干预更有效 我们将测试 ABC 干预对婴儿 RSA、母亲 RSA 和（资源匮乏）的影响。 婴儿-母亲 RSA 同步性（目标 1）我们还将测试社会文化背景的两个方面（母亲）。 文化适应和邻里社会凝聚力）作为干预效果的调节因素（目标 2）。 涉及代表性不足的人群的现有随机对照试验潜在影响将很大：这项研究将突破新的 基础，并将通过产生效应大小和统计功效估计，为以下方面奠定基础： 这项研究的下一阶段：对基于依恋的潜力进行更全面的（R01）研究 改善低收入拉丁裔家庭儿童健康状况的干预措施。