Effects of Attachment-Based Intervention on Low-Income Latinx Infants' and Mothers' Cardiac Vagal Regulation

基于依恋的干预对低收入拉丁裔婴儿和母亲心脏迷走神经调节的影响

• 批准号: 10378677
• 负责人: LISA J BERLIN
• 金额: $ 7.73万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10378677
• 关键词: Acculturation; Affect; Behavioral; Berlin; Biological; Breathing; Cardiac; Child; Child Health; Cohort Effect; Communities; Community Networks; Data Analyses; Data Collection; Development; Environment; Evaluation; Family; Foundations; Foxes; Funding; Health; Hydrocortisone; Infant; Intervention; Investigation; Latinx; Link; Literature; Low income; Mediating; Modeling; Mothers; Neighborhoods; Outcome; Pathway interactions; Phase; Play; Population; Psychophysiology; Regulation; Research; Resources; Rest; Risk; Role; Sampling; Secure; Security; Series; Sinus Arrhythmia; Skin; Stress; Testing; Underrepresented Populations; Variant; base; biobehavior; care giving burden; caregiving; experience; experimental study; high risk; high risk infant; improved; indexing; intervention effect; maternal caregiving; maternal stress; physical conditioning; programs; public health relevance; respiratory; response; social cohesion; social culture; stressor

According to the biological embedding model, early environments get “under the skin” via stress regulation to influence physical health. Consistent with this model, attachment research links supportive caregiving to health outcomes, but underlying psychophysiological mechanisms are not well understood. This R03 proposal focuses on cardiac vagal tone, an important index of stress regulation that has been associated with early caregiving and physical health. In particular, we will examine infants' and mothers' respiratory sinus arrhythmia (RSA) at rest and in response to mild stressors. We hypothesize that attachment-based interventions that promote sensitive caregiving and infants' and mothers' stress regulation have the potential to support good physical health. The extant literature suggests that mothers' sensitive caregiving may influence infant RSA, maternal RSA, and RSA synchrony, but causal effects have not been tested. These effects require rigorous investigation to elucidate the developmental pathways to effective stress regulation. Results will in turn inform improvement and evaluation of attachment-based interventions and their effects on child health. Thus, experimental studies of attachment- based interventions are necessary to test whether and how caregiving causally affects the development of RSA, and for whom such interventions are most effective. The proposed study will extend PI Berlin's recently completed RCT testing the Attachment and Biobehavioral Catch-up (ABC) program with low-income, Latinx mothers and their infants (N = 181). RCT findings to date illustrate positive effects on maternal sensitivity and infant behavioral and cortisol regulation. In a supplemental data collection, electrocardiographic recordings, from which RSA scores can be constructed, were collected from both infants and mothers during a series of mild stressors. Supplemental funding is required to (a) clean, edit, and calculate RSA values; and (b) conduct data analysis. The sample reflects an underrepresented and potentially highly informative population in which to study the associations among caregiving and stress regulation, as sociocultural context may play an especially important role in stress regulation for Latinx families. Therefore, increased maternal sensitivity may be more important – and attachment-based intervention more effective - for Latinx families characterized by higher-risk (lower-resourced) sociocultural contexts. We will test ABC intervention effects on infant RSA, maternal RSA, and infant-mother RSA synchrony (Aim 1). We will also test two aspects of sociocultural context (maternal acculturation and neighborhood social cohesion) as moderators of intervention effects (Aim 2). By leveraging an existing RCT involving an underrepresented population potential impact will be high: This study will break new ground and will create, through the generation of effect sizes and statistical power estimations, a foundation for the next phase of this research: a more comprehensive (R01) study of the potential of attachment-based intervention to improve children's health outcomes in low-income Latinx families.

根据生物嵌入模型，早期环境通过压力调节“在皮肤下” 影响身体健康。与该模型一致，依恋研究将支持护理与健康联系起来 结果，但潜在的心理生理机制尚不清楚。此R03提案重点 在心脏迷走神经上，这是与早期护理和 身体健康。特别是，我们将检查婴儿和母亲的呼吸窦性心律失常（RSA）的休息和 响应轻度压力源。我们假设基于附件的干预措施促进敏感 照料和婴儿和母亲的压力调节有可能支持良好的身体健康。这 现有文献表明，母亲的敏感照顾可能会影响婴儿RSA，Mater RSA和RSA 同步，但尚未测试因果效应。这些影响需要严格的投资才能阐明 有效压力调节的发展途径。结果反过来将为改进和评估 基于依恋的干预措施及其对儿童健康的影响。那是依恋的实验研究 基于干预措施对于测试护理是否偶尔影响发展的必要措施是必要的 RSA的及其最有效的干预措施。拟议的研究将扩大柏林的PI 最近完成了RCT测试，以低收入为附件和生物狂行追踪（ABC）程序， 拉丁母亲及其婴儿（n = 181）。迄今为止的RCT发现说明了对母体灵敏度的积极影响 以及婴儿的行为和皮质醇调节。在补充数据收集中，心电图记录， 可以从中构建RSA分数，在一系列中间的婴儿和母亲那里收集。 压力源。需要补充资金才能（a）清洁，编辑和计算RSA值； （b）进行数据 分析。该样本反映了一个人数不足且潜在的信息丰富的人群 照顾和压力调节之间的关联，因为社会文化背景可能会特别有 在拉丁裔家族的压力调节中的重要作用。因此，提高母体敏感性可能更多 对于以高风险为特征的拉丁裔家庭，重要的，基于依恋的干预措施更有效 （资源较低的）社会文化背景。我们将测试ABC干预对婴儿RSA，母体RSA和 婴儿母体RSA同步（AIM 1）。我们还将测试社会文化背景的两个方面（母性 适应和邻里社会凝聚力）作为干预效果的主持人（AIM 2）。通过利用一个 现有的RCT涉及人口不足的潜在影响不足的RCT将很高：这项研究将破坏新的 地面并将通过产生效应大小和统计能力估算的创造 这项研究的下一阶段：基于依恋的潜力的更全面的研究（R01） 干预以改善低收入拉丁裔家庭的儿童健康状况。