Listening effort under auditory masking conditions in persons with acquired aphasia

获得性失语症患者在听觉掩蔽条件下的听力努力

• 批准号: 10208854
• 负责人: Sarah Noelle Villard
• 金额: $ 8.96万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-03 至 2023-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10208854
• 关键词: Acoustics; Acquired Aphasia; Address; Affect; Age; Aphasia; Area; Auditory; Brain; Chronic; Cognitive; Communication; Communication impairment; Communities; Community Participation; Complex; Comprehension; Data; Development; Electroencephalography; Environment; Exhibits; Expenditure; Family; Fatigue; Goals; Hearing; Impairment; Individual; Investigation; Language; Language Disorders; Lead; Lesion; Linguistics; Location; Magnetic Resonance Imaging; Masks; Measures; Mentors; Methodology; Mission; National Institute on Deafness and Other Communication Disorders; Outcome; Patient Self-Report; Performance; Persons; Phase; Population; Psychoacoustics; Pupil; Quality of life; Rehabilitation therapy; Reporting; Research; Resources; Restaurants; Scientist; Short-Term Memory; Signal Transduction; Source; Speech; Stress; Stroke; Structure; Training; Treatment outcome; United States; Work; age related; career; chronic stroke; clinically relevant; experience; hearing impairment; indexing; negative affect; operation; perceived stress; skills; social; social engagement; social implication; sound; speech processing; speech recognition; stroke-induced aphasia; tool

Project Summary/Abstract Aphasia is a common consequence of stroke, affecting approximately 1 million individuals in the United States and often persisting as a chronic condition. A growing body of work suggests that persons with chronic aphasia (PWA) are poorer than age- and hearing-matched controls at understanding speech when background sounds, or auditory maskers, are present. However, little is currently known about how auditory masking affects listening effort in PWA. Listening effort—that is, the cognitive resources directed towards decoding an auditory signal—is a key construct in the study of receptive speech processing. The presence of auditory maskers can often result in substantial increases in listening effort, which in turn can have significant negative ramifications for listeners, such as increased stress and fatigue, as well as the availability of fewer remaining resources to direct towards concurrent cognitive-linguistic operations. Because auditory masking is ubiquitous in real-world social and community environments (e.g. restaurants, stores, family/social gatherings), gaining a better understanding of this topic is crucial in understanding everyday communication in PWA. This proposal therefore consists of a close investigation into listening effort in aphasia under auditory masking conditions. This investigation is part of a comprehensive training plan that will allow the candidate to gain proficiency in specific tools—including pupillometry, electroencephalography (EEG), and structural magnetic resonance imaging (MRI)—and apply them to address several research aims, under the advisement of a mentoring team of experienced scientists. During the mentored phase, the project will aim to examine whether listening effort is higher in PWA than in age- and hearing-matched controls, as well as to identify possible relationships between brain lesion location and listening effort in PWA. During this initial phase, the candidate will receive training in pupillometry and EEG as measures of listening effort, as well as in structural MRI to collect data on lesion location, in order to compare listening effort in PWA vs controls. During the independent phase, the project will aim to assess the effects of several specific types of auditory masker manipulations, including masker type and location, on listening effort in PWA and controls. Finally, the effect of increased listening effort on verbal working memory in PWA will be directly examined. Throughout the project, careful consideration will be given to differentiating between the effects of aphasia, age, and hearing loss on listening effort. Results will provide critical information about how auditory masking affects PWA, and may have implications for social engagement, community participation, and quality of life in this population. Completion of the project will also allow the candidate to launch an independent research career investigating clinically relevant questions in aphasia and related neurogenic cognitive-communication disorders.

项目摘要/摘要 失语症是中风的普遍结果，影响了美国大约100万个人 状态并经常持续为慢性病。越来越多的工作表明患有慢性的人 失语症（PWA）比年龄和听力匹配的对照在理解语音时较差 存在声音或听觉掩护者。但是，目前对听觉掩盖的了解知之甚少 影响PWA的听力工作。听力努力 - 也就是说，用于解码的认知资源 听觉信号 - 是接受语音处理研究的关键构造。听觉的存在 掩护者通常会导致听力努力大幅增加，这反过来可能具有显着的负面 听众的后果，例如增加压力和疲劳，以及剩余的剩余较少的可用性 直接朝着并发的认知语言操作的资源。因为听觉掩盖无处不在 在现实世界中的社会和社区环境中（例如餐馆，商店，家庭/社交聚会），获得了 更好地理解该主题对于理解PWA的每天沟通至关重要。 因此，该提案包括对听觉下的失语症的聆听努力的密切调查 掩盖条件。这项投资是一项全面培训计划的一部分，该计划将使候选人能够 提高特定工具的熟练程度 - 包括化学计量学，脑电图（EEG）和结构 磁共振成像（MRI） - 并在建议下应用它们来解决一些研究目标 由经验丰富的科学家组成的心理团队。在心理阶段，该项目将旨在检查 PWA的听力努力是否高于年龄和听力匹配的对照，并确定 PWA中脑病变位置与听力工作之间的可能关系。在此初始阶段， 候选人将接受化学和脑电图的培训，作为听力工作的测量以及结构的培训 MRI收集有关病变位置的数据，以比较PWA与控件中的听力工作。在 独立阶段，该项目将旨在评估几种特定类型的听觉遮罩的影响 在PWA和控件中的听力工作中，包括掩蔽类型和位置在内的操作。最后，效果 将直接检查对PWA中口头工作记忆的听力工作。在整个项目中， 仔细考虑将失语，年龄和听力损失的影响区分 听力。结果将提供有关听觉掩蔽对PWA的影响的关键信息，并可能具有 对社会参与，社区参与和该人群生活质量的影响。完成 该项目还将允许候选人在临床上发起独立研究职业 失语症和相关神经源性认知通讯障碍中的相关问题。

项目成果

Energetic and informational masking place dissociable demands on listening effort: Evidence from simultaneous electroencephalography and pupillometrya).

• DOI: 10.1121/10.0020539
• 发表时间: 2023-08-01
• 期刊: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
• 影响因子: 2.4
• 作者: Villard, Sarah;Perrachione, Tyler K;Lim, Sung-Joo;Alam, Ayesha;Kidd, Gerald
• 通讯作者: Kidd, Gerald