Efficacy of a Couple-focused, Tailored, Symptom Self-Management mHealth Intervention for Prostate Cancer Patients and Partners

以夫妻为中心、量身定制的症状自我管理移动健康干预措施对前列腺癌患者和伴侣的功效

• 批准号: 10200890
• 负责人: Lixin Song
• 金额: $ 47.12万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-25 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10200890
• 关键词: Address; Adherence; Adverse effects; Affect; Aftercare; Age; American Cancer Society; Attitude; Behavior; Cancer Advocacy; Cancer Center; Cancer Patient; Cancer Survivor; Cancer Survivorship; Caregivers; Caring; Cellular Phone; Chronic; Chronic Disease; Communication; Communities; Computers; Control Groups; Couples; Diagnosis; Distress; Education; Effectiveness; Electronic Mail; Ethnic Origin; Family; Fatigue; Geography; Goals; Guidelines; Health Technology; Health behavior; Home; Hormonal; Impairment; Individual; Institute of Medicine (U.S.); Internet; Intervention; Intestines; Knowledge; Learning Module; Localized Disease; Malignant Neoplasms; Malignant neoplasm of prostate; Methodology; Methods; Modeling; National Cancer Institute; National Institute of Nursing Research; Newly Diagnosed; Oncology; Online Systems; Operative Surgical Procedures; Pain; Participant; Patient Care; Patients; Persons; Physicians' Offices; Pilot Projects; Prostate Cancer therapy; Quality of life; Race; Radiation; Randomized Clinical Trials; Randomized Controlled Trials; Regional Disease; Reporting; Research; Resources; Self Care; Self Efficacy; Self Management; Sleep disturbances; Social support; Source; Stress and Coping; Support Groups; Supportive care; Survivors; Symptoms; Tablets; Telephone; Testing; Text; Time; Travel; Treatment-Related Cancer; Uncertainty; acronyms; active method; base; cancer therapy; cancer type; care providers; cohort; coping; design; education resources; efficacy testing; emotional distress; evidence base; experience; hormone therapy; improved; innovation; intimate behavior; mHealth; men; novel; patient-clinician communication; peer support; population based; preference; primary caregiver; programs; response; satisfaction; secondary outcome; side effect; skills; skills training; survivorship; symptom management; symptom self management; symptom treatment; symptomatic improvement; theories; tool; treatment as usual; treatment effect; urinary; usability; user-friendly; web portal; web site

PROJECT SUMMARY/ABSTRACT Over 180,000 men will be diagnosed with localized prostate cancer in 2016 and 92% of these men will have localized or regional disease. Fortunately, treatment with curative intent (surgery or radiation with/without hormone therapy) provides long-term cancer-free survival. However, survivors experience urinary, sexual, bowel and hormonal symptoms, general distress, pain, fatigue, and sleep disturbance. For men in an intimate relationship, these symptoms disrupt couple’s relationships and intimacy, and reduce quality of life (QOL) of both patients and their partners who are often their primary caregivers. Symptom effects may have as great or greater impact on their partners’ QOL than on patients’ own QOL. Management of the negative effects of cancer and its treatment is a significantly under-addressed supportive care need for these men and their intimate partners. Most existing online programs are not couple-focused or use generalized “one-size fits all” approaches that have fallen short of improving QOL. Existing in-person couple-focused programs are expensive and inconvenient because of the time and travel required. To address these unmet supportive care needs, Dr. Song led an interdisciplinary team to develop and pilot test the usability and feasibility of an evidence-based, couple-focused, tailored mobile health (mHealth) intervention, “Prostate Cancer Education & Resources for Couples” (PERC). Based on the adapted stress-coping theoretical framework and developed with stakeholder involvement, PERC aims to improve QOL for both patients and partners through enhancing positive appraisals, self-efficacy, social support, and healthy behaviors for symptom management. Using mHealth technologies, PERC provides comprehensive, user-friendly content, and uses tailoring and personalization features designed to increase personal relevance of, and couples’ accessibility to PERC modules. We propose to rigorously test the efficacy of PERC using a population-based, geographically and demographically diverse cohort in a randomized controlled trial. The specific aims are: Primary Aim: Assess if patients and partners receiving PERC will report greater improvement in their cancer-related QOL scores than those in the control group (usual care plus the National Cancer Institute (NCI) prostate cancer website) at 4, 8, and 12 months post-baseline. Secondary Aim: Test if patients and partners in PERC will report significantly more positive appraisals and higher levels of coping resources at follow-ups than those in the control group. Exploratory Aim: Determine if patient race and ethnicity, education, type of treatment, or couples’ relationship quality moderate the effects of PERC on patient and partner QOL at follow-ups. This study will provide a novel model for self-managing chronic illness symptoms that impact couples’ relationships, intimacy, and QOL. It addresses the National Institute of Nursing Research’s (NINR) goal to develop and test new strategies for symptom self-management to help patients and caregivers better manage their illness and improve QOL. It also responds to calls for programs from the Institute of Medicine (IOM) and American Cancer Society (ACS) to address treatment-related effects and improve survivors’ QOL.

项目摘要/摘要 2016年将被诊断出18万名男性将被诊断出患有局部前列腺癌，其中92％的男性将拥有本地化或 幸运的是，具有治疗意图的治疗 长期癌症生存。 在亲密关系中，男性的痛苦，疼痛，疲劳和睡眠障碍。 人际关系和亲密关系，并降低患者和伴侣的生活质量（QOL） 护理人员的症状影响可能对他们的伴侣产生巨大的影响 对癌症及其治疗的负面影响的管理是一种严重缺乏的支持护理需求 这些人及其亲密伴侣。 适合所有“跌倒的矮人的方法” 并需要时间和旅行的不便来满足这些支持的护理需求 跨学科开发和试点测试循证，夫妇量身定制的可用性和可行性 移动健康（MHealth）干预，“夫妻的前列腺癌教育和资源”（PERC） PERC旨在改善压力的理论框架，并使用危险危险持有者参与开发，旨在改善 通过增强积极的掌声，自我效能感，社会支持和健康行为 用于使用MHealth技术的症状管理。 裁缝和个性化功能旨在提高个人意义 模块。我们建议使用基于人群的，地理和 在随机对照试验中，人口多样的队列是：主要目的：评估患者是否 接受PERC的及其癌症相关的QoL scoles的及其对控制的QoL scoles的改善将更大 小组（通常的护理以及国家癌症研究所（NCI）前列腺癌网站）在基线后4、8和12个月。 次要目的：测试患者，派对以及PERC是否会明显更积极的评估和更高的左撇子 在对照组中应对后续资源的应对。 种族，教育，治疗类型或夫妻的关系质量使PERC对患者的影响和 随访的伴侣QOL将主要用于自我管理的慢性疾病症状的新型模型 夫妻的关系，亲密关系和QoL。 制定和测试症状自我管理的新策略，以帮助患者和护理人员更好地控制疾病 并改善QOL。 社会（ACS）解决与信任相关的影响并改善幸存者的质量。

项目成果

Testing the efficacy of a couple-focused, tailored eHealth intervention for symptom self-management among men with prostate cancer and their partners: the study protocol.

• DOI: 10.1186/s13063-021-05948-5
• 发表时间: 2022-01-04
• 期刊: Trials
• 影响因子: 2.5
• 作者: Song L;Nielsen ME;Chen RC;Rini C;Keyserling TC;Idiagbonya E;Fuller GP;Northouse L;Palmer MH;Tan X
• 通讯作者: Tan X

Systematic review of illness uncertainty management interventions for cancer patients and their family caregivers.

• DOI: 10.1007/s00520-020-05931-x
• 发表时间: 2021-08
• 期刊: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
• 作者: Guan T;Qan'ir Y;Song L
• 通讯作者: Song L

Factors related to tracheostomy timing and ventilator weaning: findings from a population in Northern Taiwan.

与气管切开时机和呼吸机脱机相关的因素：来自台湾北部人群的调查结果。

• DOI: 10.1111/crj.12492
• 发表时间: 2018
• 期刊: The clinical respiratory journal
• 作者: Chen,Hui-Chin;Song,Lixin;Chang,Hsin-Chieh;Hsu,Min-Tao
• 通讯作者: Hsu,Min-Tao

Intelligent Conversational Agents in Patient Self-Management: A Systematic Survey Using Multi Data Sources.

患者自我管理中的智能会话代理：使用多数据源的系统调查。

• DOI: 10.3233/shti190661
• 发表时间: 2019
• 期刊: Studies in health technology and informatics
• 作者: Xing,Zhaopeng;Yu,Fei;Qanir,YousefAMustafa;Guan,Ting;Walker,Jennifer;Song,Lixin
• 通讯作者: Song,Lixin

Research Agenda of the Oncology Nursing Society: 2019-2022.

肿瘤护理学会研究议程：2019-2022。

• DOI: 10.1188/19.onf.654-669
• 发表时间: 2019
• 期刊: Oncology nursing forum
• 影响因子: 1.9
• 作者: VonAh,Diane;Brown,CarltonG;Brown,SusanJ;Bryant,AshleyL;Davies,Marianne;Dodd,Marylin;Ferrell,Betty;Hammer,Marilyn;Knobf,MTish;Knoop,TeresaJ;LoBiondo-Wood,Geri;Mayer,DeborahK;Miaskowski,Christine;Mitchell,SandraA;Song,Li
• 通讯作者: Song,Li