Administrative Core

行政核心

• 批准号: 10200816
• 负责人: TIMOTHY RAYMOND FENNELL
• 金额: $ 17.91万
• 依托单位: RESEARCH TRIANGLE INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-05 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10200816
• 关键词: Budgets; Child Health; Client; Clinical Laboratory Information Systems; Communication; Communication Methods; Communities; Consultations; Contracts; Data; Data Analyses; Deposition; Development; Ensure; Epidemiology; Food; Funding; Guidelines; Health; Human; Information Dissemination; Infrastructure; International; Knowledge; Laboratories; Measures; Metabolism; Methods; National Institute of Environmental Health Sciences; Occupational activity of managing finances; Persons; Phase; Preparation; Procedures; Progress Reports; Protocols documentation; Quality Control; Reporting; Research; Research Design; Research Personnel; Resources; Role; Sampling; Science; Scientist; Self Assessment; Services; Ships; TimeLine; Training; United States National Institutes of Health; Voting; Work; Writing; analytical method; data acquisition; data repository; data submission; experience; meetings; member; metabolomics; metabolomics resource; method development; novel strategies; operation; outreach; programs; quality assurance; sample collection; scientific organization; skills; symposium; web site; working group

Project Summary/ Abstract (Administrative Core) The Administrative Core (AC) will provide overall administrative and organizational oversight and management of the proposed HHEAR Hub. The HHEAR Hub AC will coordinate the management of the scientific, organizational, financial, and contractual activities, and facilitate communication among the HHEAR Hub members. The AC will communicate with the HHEAR Coordinating Center (HHEAR CC) and coordinate all of the HHEAR Hub activities with the Data Repository Analysis and Science Center (DAC). The HHEAR Hub AC will organize consultations with the CC and the HHEAR program clients to provide input for study design, sample collection, storage, material needs, and shipment, develop statements of work and budgets, and ensure data deposition. The HHEAR Hub AC will ensure staff participate in conference calls and in-person meetings with the HHEAR Network to discuss and share methods, workflows, and to develop data deposition requirements. This will include participation in the HHEAR Hub working groups, ring trials, and cross-laboratory comparisons. The HHEAR Hub AC will provide a venue to develop and share information for new approaches in data capture or data interpretation in this HHEAR Hub, and across the HHEAR consortium. The AC will ensure that our communications and methods are refined to meet clients’ needs. The AC will also ensure that a Laboratory Information System (LIMS) is used to track all aspects of projects, from initial client communication through sample receipt, data analysis, and reporting. The HHEAR Hub AC will ensure that the HHEAR Hub has protocols and quality control measures in place for all steps in the work flow, and that quality audits are made by independent staff. The AC will assess the needs of the research community by attending consortia meeting, epidemiology conferences, and holding symposia to gather stakeholders’ opinions. The HHEAR Hub will be led by Multiple PI (MPI), Dr. Timothy Fennell (RTI), who has served as the PI of a NIEHS-funded Children’s Health Exposure Analysis Resource (CHEAR) Hub for the past 3 years; MPI Dr. Susan Sumner (UNC Chapel Hill), who has served as the PI of the NIH Eastern Regional Comprehensive Metabolomics Resource Core (ERCMRC) since 2012; and MPI Dr. Xiuxia Du (UNC Charlotte), who is a PI in the Phase 2 NIH Common Fund Metabolomics Program. Dr. Fennell will direct the AC for the HHEAR Hub, will be the voting member of the EC, and will direct the DC. Dr. Sumner will direct the UARC, and Dr. Du will direct the Computational Exposome (CE) workflows. All MPIs will serve on the SC and be voting members.

项目摘要/摘要（行政核心） 行政核心 (AC) 将提供全面的行政和组织监督 HHEAR Hub AC 将协调 HHEAR Hub 的管理。 科学、组织、财务和合同活动，并促进 HHEAR 之间的沟通 中心成员将与 HHEAR 协调中心 (HHEAR CC) 进行沟通并进行协调。 HHEAR 中心与数据存储分析和科学中心 (DAC) 的所有活动。 Hub AC 将组织与 CC 和 HHEAR 项目客户的磋商，为研究提供投入 设计、样品采集、存储、材料需求和运输，制定工作和预算报表， 并确保数据存储 HHEAR Hub AC 将确保员工参加电话会议和亲自参加。 与 HHEAR Network 举行会议，讨论和分享方法、工作流程并开发数据存储 这将包括参与 HHEAR Hub 工作组、环形试验和跨实验室。 HHEAR Hub AC 将提供一个开发和共享新方法信息的场所。 该 HHEAR 中心以及整个 HHEAR 联盟的数据捕获或数据解释。 确保我们的沟通和方法得到改进以满足客户的需求。审计委员会还将确保： 实验室信息系统（LIMS）用于跟踪项目的各个方面，从最初的客户 HHEAR Hub AC 将通过样本接收、数据分析和报告进行沟通。 HHEAR Hub 为工作流程中的所有步骤制定了协议和质量控制措施，并且质量 审计由独立工作人员进行，审计委员会将通过参加来评估研究界的需求。 联合体会议、流行病学会议和召开研讨会以收集利益相关者的意见。 HHEAR Hub 将由 Multiple PI (MPI) Timothy Fennell 博士 (RTI) 领导，他曾担任一家公司的 PI 过去 3 年，NIEHS 资助了儿童健康暴露分析资源 (CHEEAR) 中心； Susan Sumner（北卡罗来纳大学教堂山分校），曾担任 NIH 东部地区综合研究所的 PI 自 2012 年起担任代谢组学资源核心 (ERCMRC)；以及 MPI 杜秀霞博士（北卡罗来纳大学夏洛特分校），她是该中心的 PI Fennell 博士将指导 HHEAR 中心的第二阶段 NIH 共同基金代谢组学计划。 是 EC 的投票成员，并将指导 DC。 Sumner 博士将指导 UARC，Du 博士将指导。 所有 MPI 都将在 SC 中服务并成为投票成员。