Pilot and Feasibility Program

试点和可行性计划

• 批准号: 10361548
• 负责人: AMITABH CHAK
• 金额: $ 17.59万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-02-15 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10361548
• 关键词: Advisory Committees; Applications Grants; Area; Award; Categories; Clinic; Collaborations; Development; Digestive System Disorders; Fostering; Foundations; Funding; Goals; Grant; Inflammation; Investigation; Investments; K-Series Research Career Programs; Liver diseases; Metabolism; Midwestern United States; Mission; National Institute of Diabetes and Digestive and Kidney Diseases; Outcome; Peer Review; Peer Review Grants; Privatization; Process; Progress Reports; Qualifying; Research; Research Institute; Research Personnel; Resources; Review Committee; Science; Series; Study Section; Talents; Translating; Trust; United States National Institutes of Health; Universities; Update; Work; base; career development; cost; feasibility research; innovation; interest; large bowel Crohn' s disease; member; minority investigator; programs; research study; skills; success; symposium; tumorigenesis; Advisory Committees; Applications Grants; Area; Award; Categories; Clinic; Collaborations; Development; Digestive System Disorders; Fostering; Foundations; Funding; Goals; Grant; Inflammation; Investigation; Investments; K-Series Research Career Programs; Liver diseases; Metabolism; Midwestern United States; Mission; National Institute of Diabetes and Digestive and Kidney Diseases; Outcome; Peer Review; Peer Review Grants; Privatization; Process; Progress Reports; Qualifying; Research; Research Institute; Research Personnel; Resources; Review Committee; Science; Series; Study Section; Talents; Translating; Trust; United States National Institutes of Health; Universities; Update; Work; base; career development; cost; feasibility research; innovation; interest; large bowel Crohn' s disease; member; minority investigator; programs; research study; skills; success; symposium; tumorigenesis

PILOT AND FEASIBILITY PROGRAM PROJECT SUMMARY The Cleveland DDRCC Pilot and Feasibility (P and F) Program is one of the fundamental pillars for the intellectual vitality and success of our Center. The Program directly supports the Center’s stated mission to foster innovation in the area of digestive disease-related research through the support of collaborative research, collaboration, and career development. The overall goal of the P and F program is to grow the number of investigators successfully performing research in the thematic areas of Digestive Inflammation/Tumorigenesis and Liver Disease/Metabolism at Case Western Reserve University (CWRU) Center and the Cleveland Clinic Foundation’s Lerner Research Institute (CCF LRI) by providing resources to develop new pilot and/or feasibility research studies that will lead to competitive peer-reviewed grant applications. The program, directed by Dr. Amitabh Chak, has a focus using P and F awards to support the development of independent research programs for junior investigators with an interest in digestive diseases research. The program also seeks to attract talented, established investigators in other fields to apply their research skills and expertise to digestive disease-related investigations. A call for applications is held each spring, and the program generally receives 20-30 proposals per year. The P and F Scientific Review Committee oversees peer-review of all qualifying applications, including both an internal review process and external review by members of the Cleveland DDRCC External Advisory Committee. The Center funds up to four $25,000 awards per year with NIDDK funding, as well as up to an additional two awards per year supported by institutional commitments. Awards are for one year, but recipients can apply for a second year of funding when needed. The P and F Program annually tracks the outcomes of all current and prior P and F Award recipients, and provides regular Progress Report updates to the NIDDK. We are particularly proud of the high level of success seen with our P and F Program during the previous funding cycle, with seven of our 15 P and F Awardees from 2015-2018 going on obtain peer-reviewed NIH or foundation grants based on work generated through their P and F project (including four K awards, one R01, one R21 for minority investigators, one P20 sub-project PI, two Crohn’s and Colitis Foundation Senior Research Awards, and one Helmsley Trust Award). P and F awardees have also been active in contributing to the enrichment programs of the Cleveland DDRCC, including founding the Young Investigators Network and its highly popular “Mock Study Section”, presenting their P and F projects at the annual Midwest DDRCC Alliance Research Symposium (hosted by the Cleveland DDRCC Mar 5-6, 2018), and organizing and participating in the Young Investigators Symposium included within the biannual two-day Cleveland IDEAS Symposium.

飞行员和可行性计划项目摘要 克利夫兰DDRCC飞行员和可行性（P和F）计划是该计划的基本支柱之一 我们中心的智力活力和成功。该计划直接支持该中心陈述的使命 通过支持合作，促进与消化疾病有关的研究领域的创新 研究，协作和职业发展。 P和F计划的总体目标是增长 研究人员数量成功地在消化系统的主题领域进行研究 Case Western Reserve University（CWRU）的炎症/肿瘤发生和肝病/代谢 中心和克利夫兰诊所基金会的Lerner研究所（CCF LRI）通过提供资源 开发新的飞行员和/或可行性研究，这些研究将导致竞争性同行评审的赠款 申请。该计划由Amitabh Chak博士执导，使用P和F奖项来支持该计划 针对对消化疾病感兴趣的初级研究人员开发独立的研究计划 研究。该计划还旨在吸引其他领域的才华横溢的调查员，以应用其 研究技能和专业知识，用于消化疾病相关的研究。每个人都举行了申请的电话 春季，该计划通常每年收到20-30个建议。 P和F科学评论 委员会监督所有合格申请的同行评审，包括内部审查程序和 克利夫兰DDRCC外部咨询委员会成员的外部审查。中心资金达到 NIDDK资助每年四个25,000美元的奖项，每年额外额外两个奖项 受机构承诺的支持。奖项持续了一年，但接收者可以申请第二年 需要时资金。 P和F计划每年跟踪所有当前和先前P和F的结果 授予获奖者，并为NIDDK提供定期的进度报告更新。我们为 在上一个融资周期中，我们的P和F计划在我们的P和F计划中取得了很高的成功，我们有七个 2015 - 2018年的15 P和F获奖者将根据工作获得同行评审的NIH或基金会赠款 通过他们的P和F项目生成（包括四个K奖，一项R01，一个R21，用于少数族裔调查员，一个 P20子项目PI，两个Crohn's and Colitis Foundation高级研究奖和一项Helmsley Trust奖）。 P和F获奖者还积极为克利夫兰DDRCC的丰富计划做出贡献 包括创立年轻调查员网络及其非常受欢迎的“模拟研究部分”，展示了他们的 中西部DDRCC联盟研究研讨会上的P和F项目（由Cleveland DDRCC主持 2018年3月5日至6日），组织和参加年轻调查人员的研讨会 双年度为期两天的克利夫兰思想研讨会。