Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment

先进的失明导航空间运动康复

• 批准号: 10200050
• 负责人: Lora T. Likova
• 金额: $ 48.11万
• 依托单位: SMITH-KETTLEWELL EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10200050
• 关键词: Auditory; Behavioral; Blindness; Brain; Brain imaging; Cognition; Cognitive; Data; Databases; Decision Making; Development; Diffusion Magnetic Resonance Imaging; Employment; Environment; Etiology; Face; Functional Magnetic Resonance Imaging; Goals; Grant; Hand; Image; Independent Living; Individual; Investigation; Knowledge; Learning; Life; Literature; Location; Locomotion; Maintenance; Manuals; Maps; Measures; Memory; Methods; Modality; Multimodal Imaging; Neuronal Plasticity; Neurosciences; Performance; Plant Roots; Population; Problem Solving; Production; Protocols documentation; Psyche structure; Psychological Transfer; Rehabilitation therapy; Research; Route; Running; Self-Help Devices; Short-Term Memory; Stimulus; Structure; Tactile; Technology Assessment; Testing; Time; Training; Translating; Travel; Vision; Visual impairment; Visually Impaired Persons; aging brain; base; blind; cognitive enhancement; cognitive function; cognitive skill; design; flexibility; haptics; imaging platform; improved; innovation; innovative technologies; interdisciplinary approach; mental representation; multidisciplinary; multimodality; neuroimaging; novel; novel strategies; operation; programs; relating to nervous system; sight restoration; skills; spatial memory; theories; tool; virtual reality system; visual motor; way finding; web-accessible

Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment ABSTRACT We propose a radical new multidisciplinary approach to navigation training in blindness and visual impairment. Successful navigation requires the development of an accurate and flexible mental, or cognitive, map of the navigational space and of the route trajectory required to travel from the current to the target location. The Cognitive-Kinesthetic (C-K) Rehabilitation Training that we have developed in the preceding period utilizes a unique form of blind memory-guided drawing to develop cognitive mapping to a high level of proficiency. Particular reliance must be placed on such mental maps (supported only by tactile and auditory inputs), and on the ability to use them effectively for spatiomotor control, when vision with its built-in spatial functionality is lost. There is, however, a fundamental gap in the practice of Orientation and Mobility (O&M), which is the lack of a specific emphasis on enhancement of these cognitive roots of spatiomotor activity, despite their known importance for navigation in the visually impaired. We therefore propose a rigorous multidisciplinary approach to this issue, which lies at the intersection of the fields of spatiomotor rehabilitation, blindness assessment technologies, and brain function, each a focus of one Specific Aim. To train the spatial cognition abilities underlying successful navigation, the current proposal aims to translate the power of the C-K Rehabilitation Training, which we developed in the preceding grant period for the manual domain of operation, to the domain of navigation. The blind and visually impaired trainees will quickly learn how to generate precise and stable cognitive maps of haptically explored raised-line images or tactile maps, and how to use the formed cognitive maps to confidently guide both drawing ’hand navigation’ on a map-scale, and whole-body blind navigation on the macro-scale. Once translated to navigation, our preliminary data show that this efficient and enjoyable training will rapidly and sustainably enhance spatial cognition functions both for improved navigation performance and for enhancement of more general spatial cognitive skills. Beyond its practical advantages, the training will also serve as an efficient tool to drive and study training-based neuroplasticity mechanisms through a comprehensive whole-brain multimodal brain imaging platform. These neuroplastic are difficult to study properly without a rapid and effective training protocol, which has not previously been available. Taken together, the research program will overcome the relative disconnect between expanding neuroscience knowledge and approaches to practical blindness rehabilitation. The knowledge gained will in turn inform and benefit further rehabilitative developments, both in navigation proficiency and in more general cognitive function in the blind population. !

用于盲目和视觉障碍导航的先进的水疗康复 抽象的 我们提出了一种激进的新的多学科方法，用于失明和视觉 障碍。 导航空间的地图和从巡游到乌龟行驶所需的路线轨迹 位置。 时期利用一种独特的盲目记忆形式引导的认知映射到高水平 熟练程度。 听觉输入），以及在视力及时使用它们有效控制水上运动的能力 内置的空间功能丢失了。 流动性（O＆M），这是缺乏对这些认知根的增强的特定重点 尽管在视力障碍中对航行的重要性已知，但它们的空中运动活动的重要性。 因此，我们建议对这个问题进行严格的多学科方法，这在于 水疗康复，失明评估技术和大脑功能的领域，每个领域都是重点 一个特定的目的，用于训练成功导航的空间认知能力 提案旨在翻译C-K康复培训的力量，我们在前面开发的 授予手册域的授予范围，并在视觉上进行视觉范围。 有障碍的培训迅速学习学习如何进行工作。 凸起线图像或触觉图，以及如何使用形成的认知图自信地指导 在地图尺度上绘制“手导航”，并在宏观尺度上进行全身盲目导航。 转化为导航，我们的初步数据表明，令人愉快的培训将迅速，并且 可持续性增强空间认知，以提高导航性能和 增强更一般的空间认知能力。 除了实际的优势之外，该培训还将作为驾驶和学习的有效工具 基于训练的神经塑料机制综合的整体 - 脑多模式成像 平台。 以前尚未合计。 在扩大神经科学知识和实践失明康复方法之间断开连接。 收获的KnoLEDGE将依次提供信息，并使进一步的康复才能发展效率发展，均在航行中 在盲人人群中的验证和更一般的认知功能。 呢