Administrative and Bioinformatics Core

行政和生物信息学核心

• 批准号: 8768692
• 负责人: Peter A Anton
• 金额: $ 28.51万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8768692
• 关键词: Accountability; Adherence; Adhesives; Anus; Area; Bioinformatics; Clinical; Collaborations; Collection; Committee Membership; Communication; Communities; Data; Data Reporting; Database Management Systems; Development; Development Plans; Documentation; Dose; Early Diagnosis; Education; Ensure; Ethics; Financial Support; Fostering; Foundations; Goals; Group Meetings; HIV; HIV Infections; Health Insurance Portability and Accountability Act; Human Resources; Informatics; Internet; Leadership; Learning; Libraries; Link; Maintenance; Management Audit; Monitor; National Institute of Allergy and Infectious Disease; Play; Policies; Prevention; Principal Investigator; Process; Prodrugs; Progress Reports; Publications; Recurrence; Reporting; Research Infrastructure; Resources; Role; Running; Site; Strategic Planning; Structure; System; Teleconferences; Tenofovir; Time; TimeLine; United States National Institutes of Health; Update; abstracting; biomedical informatics; data management; enema administration; experience; flexibility; interest; meetings; microbicide; operation; pre-clinical; programs; prospective; rectal; rectal microbicide; repository; symposium; web site

The Administrative Core (Core A) will direct and coordinate several major areas contributing to the activities of the Development of Rectal Enema as Microbicide (DREAM) Program whose overall goal it is to develop a single dose tenofovir prodrug enema to provide one week of protection from HIV infection following unprotected receptive anal intercourse. These activities include (1) administrative oversight of the entire program including all Projects and Cores, (2) providing financial oversight of the program, (3) act as primary liaison with the NIAID/DAIDS appointed Program Officer with responsibility for the Integrated Preclinical/Clinical Program for HIV Microbicides and Biomedical Prevention U19 Program, (4) coordinate the monthly conference calls for the Steering Committee (SC) and disseminate agendas / meeting minutes in a timely fashion, (5) organize the annual IP/CP meeting, (5) in collaboration with NIAID/DAIDS, establish and provide logistical support for a Scientific Advisory Panel facilitation, and (6) undertake website maintenance, education, publication assistance, library maintenance, and general administrative support. The Core will link the various project leaders and programs as well as integrate the related milestones of each project and ensuring communication between project leaders. The SC, composed of the Principal Investigator and each Project Leader/Associate-Leader, Core Leader/Associate Leader, and select key personnel, will be the central mechanism in assuring communication between Projects, Project sites, and Cores. The Administrative Core will also produce twice-yearly internal progress reports for the SC. These will be available to interested key personnel and the NIH's Scientific Advisory Panel (SAP).

行政核心（核心 A）将指导和协调有助于促进活动的几个主要领域 开发直肠灌肠杀微生物剂 (DREAM) 计划，其总体目标是开发一种 单剂量替诺福韦前药灌肠可提供一周的 HIV 感染保护 无保护的接受性肛交。这些活动包括 (1) 对整个组织的行政监督 计划，包括所有项目和核心，(2) 提供对该计划的财务监督，(3) 作为主要 与 NIAID/DAIDS 指定的项目官员联络，负责综合 HIV 杀菌剂临床前/临床计划和 U19 生物医学预防计划，(4) 协调 每月召开指导委员会 (SC) 电话会议并以电子邮件形式传播议程/会议纪要 及时，(5) 组织年度 IP/CP 会议，(5) 与 NIAID/DAIDS 合作，建立和 为科学顾问小组的便利提供后勤支持，以及 (6) 进行网站维护， 教育、出版援助、图书馆维护和一般行政支持。核心将链接 各个项目领导者和计划，以及整合每个项目的相关里程碑和 确保项目负责人之间的沟通。 SC 由首席研究员和各 项目负责人/副负责人、核心负责人/副负责人以及选定的关键人员将成为中心 确保项目、项目站点和核心之间通信的机制。行政核心 还将为 SC 提供每年两次的内部进度报告。这些将提供给感兴趣的关键 人员和 NIH 的科学顾问小组 (SAP)。