Backyard Brains: Bringing Neurophysiology Into Secondary Schools

后院大脑：将神经生理学引入中学

• 批准号: 9983344
• 负责人: Gregory John Gage
• 金额: $ 47.01万
• 依托单位: BACKYARD BRAINS, INC.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-11-08 至 2020-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9983344
• 关键词: Action Potentials; Address; Administrator; Adopted; Affect; Amplifiers; Anatomy; Animal Model; Awareness; Behavior; Biological Sciences; Biology; Brain; Car Phone; Cognitive; Computer software; Computers; Conceptions; Devices; Dictyoptera; Discipline; Disease; Drosophila genus; Education; Educational Curriculum; Electrocardiogram; Electroencephalography; Electrophysiology (science); Engineering; Equipment; Eye; Family; Feedback; Future; Future Teacher; Goals; Growth; Gryllidae; Heart; High School Student; Human; Human body; Individual; Insecta; Institution; Instruction; Invertebrates; Investigation; Learning; Manuals; Mathematics; Measures; Medicine; Microscope; Modeling; Motor; Mus; Muscle; Music; Nerve; Nervous System Physiology; Nervous system structure; Neurons; Neurosciences; Neurosciences Research; Online Systems; Outcome; Performance; Phase; Physicians; Physics; Physiological; Physiology; Policy Maker; Population; Prosthesis; Research; Resources; Robotics; SECTM1 gene; Sales; Schools; Science; Scientist; Secondary Schools; Self Efficacy; Signal Transduction; Students; Techniques; Text; Universities; Video Games; Wireless Technology; Work; World Health; World Health Organization; base; career; commercial application; curriculum enhancement; design; experimental study; graduate student; grasp; handheld mobile device; high school; improved; innovation; instrument; learning materials; neurophysiology; neuroprosthesis; next generation; optogenetics; portability; programs; prototype; relating to nervous system; robot control; skills; teacher; tool; twelfth grade

Project Summary Deciphering how the brain functions remains one of the great challenges remaining to humanity, intriguing scientific professionals and the public equally. The notorious complexity of the nervous system results in neural diseases remaining widespread and difficult to treat. Tools for studying the brain are often difficult to use and only available to graduate students and scientists in large research universities. Providing accessible neuroscience research tools and educational equipment for high schools will accelerate neuroscience innovation by exposing future scientists, engineers, and doctors to principles of nervous system function at much earlier stages in their careers. Implementing electrophysiology and other neuroscience techniques into K12 education has historically been difficult to the lack of affordable tools combined with compelling and accessible learning materials. To address this need, we are developing a neuroscience curriculum based on graduate­level neuroscience research tools that can be used in the High School Classroom. 1) The “SpikerBox”: a family of bio­amplifiers that are easy­to­use, inexpensive (<$100), portable, and can detect and record the action potentials of the nervous system of invertebrates, action potentials of human muscles (EMG), the electrical signature of the heart (EKG), and the electrical oscillations of the human brain (EEG). 2) The “RoboRoach”: a wireless neural stimulator for investigating insect behavior. 3) The “OptoStimmer”: a fully portable mobile phone based miniature microscope and electrophysiology apparatus enabling optogenetic experiments in fruit flies in high school classrooms. 4) The “SpikerShield”: a human interface toolkit that allows students to connect their bodies’ electrical signals (from muscles, heart, eyes, and brain) into creative engineering team projects such as robotic grippers, computer mice, musical instruments, video game interfaces, and prosthetic models. 5) A Comprehensive student neuroscience text and Teacher manual that focuses on problem­based instructional neuroscience units, with guidance for managing a problem­based classroom. As neuroscience is a multi­disciplinary field encompassing biology, medicine, mathematics, and engineering, the educational tools and materials to be developed here will improve learning in STEM­related disciplines and inspire the next generation of scientists, engineers, and physicians.

项目摘要 破译大脑的功能仍然是人类剩下的重大挑战之一，很有趣 科学专业人士和公众平等。神经系统的臭名昭著的复杂性导致神经 疾病保持宽度且难以治疗。研究大脑的工具通常很难使用， 仅适用于大型研究大学的研究生和科学家。提供的可访问 神经科学研究工具和高中的教育设备将加速神经科学 通过将未来的科学家，工程师和医生暴露在神经系统功能的原则上，创新 他们职业生涯中的阶段要较早。将电生理学和其他神经科学技术实施 历史上，K12教育缺乏负担得起的工具以及引人注目的和 可访问的学习材料。 为了满足这种需求，我们正在基于研究生级别的神经科学开发神经科学课程 可以在高中教室中使用的研究工具。 1）“ SpikerBox”：一个易于体验，便宜（<$ 100），便携式和可以 检测并记录无脊椎动物神经系统的动作电位， 人类肌肉（EMG），心脏的电特征（EKG）和振荡的电振荡 人脑（EEG）。 2）“ roboroach”：一种用于研究抑制行为的无线神经刺激剂。 3）“验证器”：完全便携式手机的微型显微镜和电生理学 在高中教室的水果蝇中实现了光遗传学实验。 4）“ Spikershield”：一种允许学生连接身体电动的人界面工具包 信号（从肌肉，心脏，眼睛和大脑）进入创意工程团队，例如机器人 抓手，计算机鼠标，乐器，视频游戏界面和假肢模型。 5）专注于问题的全面学生神经科学文本和教师手册 教学神经科学单元，并在管理基于问题的课堂的指导下。 由于神经科学是一个跨学科领域，包括生物学，医学，数学和工程学，所以 这里要开发的教育工具和材料将改善与STEM相关学科的学习和 激发下一代科学家，工程师和医生。