Mid-Career Award in Patient-Oriented Drug Abuse Research

以患者为导向的药物滥用研究职业生涯中期奖

• 批准号: 8766927
• 负责人: AIMEE L MCRAE-CLARK
• 金额: $ 17.58万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8766927
• 关键词: Address; Area; Attention; Award; Biostatistical Methods; Chronic; Clinical; Clinical Research; Country; Data Collection; Development; Drug Addiction; Drug abuse; Ensure; Evidence based treatment; Faculty; Funding; Grant; Healthcare; Individual; Legal; Medical; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Midcareer Investigator Award in Patient-Oriented Research; Pharmaceutical Preparations; Play; Postdoctoral Fellow; Research; Research Activity; Research Design; Research Ethics; Research Methodology; Research Personnel; Research Training; Role; Scientist; Sex Characteristics; Substance Use Disorder; Time; Training; Training Activity; Treatment Efficacy; Underrepresented Minority; United States National Institutes of Health; Work; Writing; addiction; biological adaptation to stress; career; career development; doctoral student; endogenous cannabinoid system; human subject protection; improved; innovation; interdisciplinary collaboration; interest; patient oriented; patient oriented research; programs; public health relevance; social; success

DESCRIPTION (provided by applicant): Drug abuse and addiction are devastating and chronic conditions that place a significant medical, financial, legal and social burden on our country. Interdisciplinary collaboration combined with technical advances has resulted in unprecedented opportunities to enhance addiction treatment efficacy and durability, and reduce vulnerability to addiction. Continued progress is vital to improving existing evidenced-based treatments and developing new treatments. It is therefore critical to attract and train clinical researchers in order to ensure that a diverse pool of highly skilled scientists will be available t address these urgent health care needs. Dr. Aimee McRae-Clark is a productive mid-career investigator who has maintained consistent NIH funding for her innovative work in the area of medications development and gender differences in addictions. In addition, she has a strong track-record of attracting and successfully mentoring medical, graduate and post-doctoral students as well as junior faculty in clinical research focused on substance use disorders. The objective of this Midcareer Investigator Award in Patient-Oriented Research is to provide support for protected time so that Dr. McRae-Clark can develop a more formal, intensive program of mentored clinical research training and career development activities to promote junior scholars in the area of drug abuse and addiction. Particular emphasis will also be placed on increasing the participation of underrepresented minorities conducting patient-oriented research. In addition, she will build on her existing program of research by incorporating new proficiencies and research directions, including advanced biostatistical methods and exploration of the role the endogenous cannabinoid system plays in stress response. This award will enable her to increase the time she is able to devote to mentorship, to consolidate her training activities, and take her research activities in new and exciting directions.

描述（由申请人提供）：药物滥用和成瘾是一种破坏性的慢性疾病，给我国带来了重大的医疗、财务、法律和社会负担。跨学科合作与技术进步相结合，为提高成瘾治疗的功效和持久性并减少成瘾的脆弱性带来了前所未有的机会。持续的进展对于改善现有的循证治疗方法和开发新的治疗方法至关重要。因此，吸引和培训临床研究人员至关重要，以确保拥有多样化的高技能科学家来满足这些紧迫的医疗保健需求。 Aimee McRae-Clark 博士是一位多产的职业生涯中期研究员，她一直为她在药物开发和成瘾性别差异领域的创新工作提供 NIH 持续资助。此外，她在吸引和成功指导医学生、研究生和博士后以及专注于药物滥用障碍临床研究的初级教师方面拥有良好的记录。该以患者为导向的研究中的职业生涯中期研究员奖的目的是为受保护的时间提供支持，以便麦克雷-克拉克博士能够制定更正式、更密集的指导临床研究培训和职业发展活动计划，以促进该领域的初级学者药物滥用和成瘾。还将特别强调增加代表性不足的少数群体参与以患者为导向的研究。此外，她将在现有的研究计划的基础上，结合新的专业知识和研究方向，包括先进的生物统计方法和探索内源性大麻素系统在应激反应中的作用。该奖项将使她能够增加用于指导的时间，巩固她的培训活动，并将她的研究活动引向新的、令人兴奋的方向。