Botanical Core

植物核心

• 批准号: 9916276
• 负责人: CLAUDIA S MAIER
• 金额: $ 49.41万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9916276
• 关键词: Acids; Aging; Animals; Ashwagandha; Attention; Bar Codes; Biological; Biological Assay; Biological Availability; Botanical dietary supplements; Botanicals; Brain; Chemicals; Chemistry; Clinical Trials; Cognition; Collaborations; Coupled; Data; Drug Kinetics; Fingerprint; Funding; Future; Gene Expression; Genes; Gotu kola; Harvest; Herb; High Pressure Liquid Chromatography; Liquid Chromatography; Literature; Mass Spectrum Analysis; Materials Testing; Methodology; Methods; Monitor; Moods; NMR Spectroscopy; Neurologic; Neurons; Oregon; Outcome; Pathway interactions; Phytochemical; Plant Sources; Plasma; Preparation; Reaction; Reference Standards; Research; Research Project Grants; Resolution; Role; Spectroscopy, Fourier Transform Infrared; Testing; Thin Layer Chromatography; Triterpenes; United States National Institutes of Health; Visual; Work; aging population; analytical method; animal tissue; base; chemical fingerprinting; in vivo; interest; metabolomics; public health relevance; resilience; sleep quality

PROJECT SUMMARY_BOTANICAL CORE Many botanicals are touted to have beneficial effects on cognition, mood, sleep quality and other functions that are diminished during aging. An abiding challenge with scientific studies involving botanicals is the complexity and variability of their chemical profile as well as ambiguities in the identity and species homogeneity of botanical preparations. The proposed Botanical Dietary Supplement Research Center (BDSRC) will perform studies critical to future clinical trials of “Botanicals enhancing neurological and functional resilience in aging”. Based on

项目summary_botanical核心 许多植物因素被吹捧为对认知，情绪，睡眠质量和其他功能的有益影响 在衰老过程中减少。涉及植物学的科学研究的持续挑战是复杂性 其化学概况的变异性以及在身份和物种同质性中的歧义 植物制剂。拟议的植物饮食补充研究中心（BDSRC）将执行 对未来的临床试验至关重要的研究“植物学增强了衰老中的神经系统和功能弹性”。 基于