SUPPORT SERVICES FOR THE PREVENTION AND TREATMENT THROUGH A COMPREHENSIVE CARE CONTINUUM FOR HIV-AFFECTED ADOLESCENTS IN RESOURCE CONSTRAINED SETTINGS (PATC3H) (UG3/UH3) PROGRAM

通过全面护理连续体为资源有限环境中受艾滋病毒影响的青少年提供预防和治疗支持服务 (PATC3H) (UG3/UH3) 计划

• 批准号: 9916169
• 负责人: BARBARA DRIVER
• 金额: $ 41.62万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-12-12 至 2019-12-11
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9916169
• 关键词: Achievement; Adolescent; Affect; Africa South of the Sahara; Award; Brazil; Caring; Clinic; Collaborations; Communication; Communities; Comprehensive Health Care; Conduct Clinical Trials; Continuity of Patient Care; Country; Education; Equipment; Evaluation; Family; Funding; HIV; HIV Infections; Health; Health system; Home environment; Human Resources; Income; Individual; Infrastructure; Institutes; Intervention; Logistics; Monitor; National Institute of Child Health and Human Development; Outcome; Phase; Policies; Prevention; Public Health; Research; Research Activity; Research Personnel; Research Project Grants; Resources; Risk; Services; Structure; Task Performances; U-Series Cooperative Agreements; United States National Institutes of Health; Viral; Youth; base; improved; innovation; prevention service; programs; web site

Introduction The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) requires support for logistical and operational coordination, website and communication management, regulatory, and monitoring of research activities for the Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings (PATC3H) (UG3/UH3) Program. The NICHD and partner NIH Institutes have funded 8 PATC3H awards in Brazil and throughout sub- Saharan Africa in 2018 through a phased innovation cooperative agreement mechanism for interventions of high public health significance: The prevention of new HIV infections among adolescents at risk, and the identification of, linkage to and retention in care of, and long-term viral suppression among youth living with HIV in low-to-middle income countries with high HIV burden. Investigators will evaluate a variety of innovative combination interventions aimed at several levels, including individual, family, clinic, community, structural and education and health systems. Projects include collaborations with local agencies and regulatory bodies, including policy and program leaders, to advance achievement of the research objectives, and maximize implementation and sustainability of efficacious interventions and best practices. Objectives This Task Order will provide all the necessary services, qualified personnel, materials, equipment, and facilities needed for support of a) logistical and operational coordination, b) regulatory infrastructure and monitoring of non-registrational trials, and c) website administration and communication management of research activities for all 8 PATC3H research projects to conduct clinical trials for the evaluation of a variety of combination interventions aimed at the individual, family, clinic, community, structural and education and health systems levels to improve health outcomes among adolescents at risk for and youth living with HIV. https://www.patc3h.org/SitePages/Home.aspx The period of performance of this task order is a base year and 4 option years or a maximum of 5 years.

介绍 Eunice Kennedy Shriver国家儿童健康与人类发展研究所 （NICHD）需要支持后勤和运营协调，网站和通信 对预防和治疗的研究活动的管理，监管和监测 通过综合护理连续性，用于受艾滋病毒影响的青少年的资源限制 设置（PATC3H）（UG3/UH3）程序。 NICHD和合作伙伴NIH机构已在巴西和整个子中资助了8个PATC3H奖项 撒哈拉非洲在2018年通过分阶段的创新合作协议机制机制 高公共健康意义的干预措施：预防新的HIV感染 有风险的青少年，以及在照顾和长期病毒的识别，连接和保留率 在低艾滋病毒负担的低到中间收入国家中，艾滋病毒携带的年轻人的抑制。 研究人员将评估各种针对多个级别的创新组合干预措施， 包括个人，家庭，诊所，社区，结构和教育和卫生系统。项目 包括与地方机构和监管机构的合作，包括政策和计划负责人， 提高研究目标的实现，并最大化实施和可持续性 有效的干预措施和最佳实践。 目标 此任务订单将提供所有必要的服务，合格的人员，材料，设备和 支持a）后勤和运营协调所需的设施，b）监管基础设施 并监视非注册试验，以及c）网站管理和通信 管理所有8个PATC3H研究项目的研究活动，以进行临床试验 评估针对个人，家庭，诊所，社区， 结构，教育和卫生系统水平，以改善青少年的健康成果 患艾滋病毒的风险和青年。 https://www.patc3h.org/sitepages/home.aspx 该任务订单的执行期限为基准年份和4个选项或最多5个 年。