Evaluating the impact of a social meditation training on acute pain experience

评估社交冥想训练对急性疼痛体验的影响

• 批准号: 9908317
• 负责人: Katherine O'Connell
• 金额: $ 3.28万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-12-10 至 2021-12-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9908317
• 关键词: Acute Pain; Acute pain management; Adult; American; Attention; Behavior; Behavioral; Buffers; Compassion; Complement; Consequentialism; Data Collection; Economics; Emotional; Emotions; Enrollment; Exhibits; Family; Feeling; Fostering; Friends; Goals; Health; Individual; Investigation; Laboratories; Length; Link; Love; Measures; Mediating; Meditation; Morbidity - disease rate; Operative Surgical Procedures; Opioid Analgesics; Outcome; Pain; Pain Origin; Pain Threshold; Pain management; Parents; Participant; Patient Self-Report; Personal Satisfaction; Physiological; Prevalence; Process; Psychophysiology; Public Health; Quality of life; Questionnaires; Randomized; Randomized Controlled Trials; Reporting; Research; Role; Social Behavior; Social Environment; Social Functioning; Social Interaction; Social Network; Social Perception; Social support; Societies; Standardization; Stimulus; Surveys; System; Techniques; Testing; Time; Training; Unmarried person; Waiting Lists; Work; base; biological adaptation to stress; career; clinical pain; cost; design; endogenous opioids; experience; improved; indexing; innovation; insight; interest; mortality; negative affect; opioid use; pain outcome; pain processing; pain reduction; positive emotional state; protective factors; response; social; social engagement; social neuroscience; social stress; stress resilience

PROJECT SUMMARY AND ABSTRACT (PI: O’Connell, Katherine; 1F31AT010423-01A1) Millions of Americans suffer from difficulties managing pain. While the origin of pain can vary, a better understanding of the protective and preventative factors of pain may help alleviate its burden on society. Large and supportive social environments have recently emerged as potential protective factors. In particular, social support—which indexes the extent of emotional and tangible assistance provided by friends, family and others in an individual’s social network—has been directly associated with increased pain tolerance and reduced opioid use after surgery, suggesting social support’s beneficial effect on reducing acute pain experience. Importantly, social support exhibits the capacity to be enhanced through some forms of meditation; however, it remains unclear whether such an enhancement may correspond to altered pain experience. This project aims to assess the impact of a Loving-Kindness Meditation (LKM) training on acute pain experience in healthy adults. LKM orients individuals to engage feelings of kindness and compassion for others, which has been shown to increase feelings of connectedness with others. Subjects will be randomized to either an 8-week online LKM training or a wait-list control condition through a pre-existing parent study (NCT03894930). By incorporating additional data collection to the parent study, this project tests two aims. The first aim will examine the impact of LKM on perceived social environment and engagement in adaptive social behavior. The second aim will investigate whether LKM can reduce acute pain experience by testing for increased pain tolerance and reduced psychophysiological reactivity to pain. The second aim will also examine how changes to social functioning may be associated with changes to acute pain experience after LKM, which will improve our understanding of how LKM may work. Results will advance our basic understanding of LKM and could help delineate an innovative path to preventative acute pain management. Through this project, I will obtain training essential for my career goals including to gain experience in a randomized-controlled trial and to quantitatively measure acute pain experience.

项目摘要和摘要（PI：O'Connell，Katherine; 1F31AT010423-01A1） 数以百万计的美国人困难控制疼痛。虽然疼痛的起源可能会有所不同，但对受保护和预防性的疼痛因素有更好的了解可能有助于减轻其对社会的燃烧。庞大而受支持的社会环境最近成为潜在的受保护因素。特别是，社会支持（索引了个人社交网络中的朋友，家人和其他人提供的情感和切实援助的程度）与手术后的疼痛耐受性增加并减少OID的使用直接相关，这表明社会支持对减少急性疼痛经历的效果。重要的是，社会支持表现出通过某些形式的冥想来增强的能力。但是，尚不清楚这种增强是否可能与改变的疼痛经历相对应。该项目旨在评估恋爱冥想（LKM）培训对健康成年人急性疼痛经历的影响。 LKM使个人对他人持友善和同情心，这已被证明会增加与他人的联系。受试者将通过先前存在的父母研究（NCT03894930）随机分配为8周的在线LKM培训或等待名单控制条件。通过将其他数据收集纳入家长研究，该项目测试了两个目标。第一个目标将研究LKM对感知的社会环境和适应性社会行为的影响。第二个目标将通过测试增加疼痛耐受性并降低心理生理学对疼痛的反应性来调查LKM是否可以减少急性疼痛经历。第二个目标还将研究社会功能的变化如何与LKM后急性疼痛经历的变化有关，这将提高我们对LKM的工作方式的理解。结果将提高我们对LKM的基本理解，并可以帮助描述预防性急性疼痛管理的创新途径。通过这个项目，我将获得对职业目标至关重要的培训，包括在随机控制的试验中获得经验，并定量衡量急性疼痛体验。