NICHD Maternal-Fetal Medicine Units (MFMU) Network

NICHD 母胎医学中心 (MFMU) 网络

• 批准号: 9903408
• 负责人: Geeta K. Swamy
• 金额: $ 1.75万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-07 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9903408
• 关键词: Academic Medical Centers; Asthma; Basic Science; Biomedical Research; Birth; Birth Rate; Blindness; Cardiovascular Diseases; Caring; Cause of Death; Cerebral Palsy; Child; Chronic lung disease; Clinical; Clinical Research; Clinical Trials; Clinical and Translational Science Awards; Communities; Complex; Consultations; County; Data; Diabetes Mellitus; Discipline of Nursing; Discipline of obstetrics; Enrollment; Environment; Etiology; Exposure to; Faculty; Family; Fetal Growth Retardation; Fetal health; Genetic; Gestational Diabetes; Gynecology; Health; Health system; Hispanics; Hospitals; Hypertension; Immunization; Infant; Infant Mortality; Infectious Disease Immunology; Institute of Medicine (U.S.); Institution; Intervention; Learning; Letters; Life; Life Expectancy; Low Birth Weight Infant; Maternal-Fetal Medicine Units Network; Maternal-fetal medicine; Medical; Medical Care Costs; Midwife; Modeling; Molecular Biology; Monitor; Mothers; Multicenter Neonatal Research Network; Multicenter Studies; National Institute of Child Health and Human Development; Native Americans; Neonatology; North Carolina; Nurse Practitioners; Participant; Pathology; Patient Recruitments; Patients; Pediatrics; Perinatal; Personal Satisfaction; Pharmacology; Pharmacy facility; Population Sizes; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnant Women; Premature Birth; Premature Infant; Premature Rupture Fetal Membranes; Prenatal Diagnosis; Prenatal care; Problem behavior; Protocols documentation; Provider; Randomized Controlled Trials; Reproduction; Research; Research Design; Research Infrastructure; Research Personnel; Research Subjects; Resources; Risk; Safety; Services; Site; Survivors; Technical Expertise; Time; Translational Research; Treatment Efficacy; United States National Institutes of Health; Universities; University Hospitals; Woman; Work; adverse pregnancy outcome; burden of illness; care delivery; clinical research site; cost; cost effectiveness; diabetes risk; disability; epidemiology study; experience; faculty research; fetal; follow-up; health of the mother; hearing impairment; high risk; improved; innovation; multiple disability; novel; participant retention; patient population; perinatal complications; perinatal health; pregnancy hypertension; premature; preterm premature rupture of membranes; prevent; public health relevance; racial difference; racial disparity; randomized trial; recruit; response; secondary analysis; sociodemographics; success; translational medicine; working group

 DESCRIPTION (provided by applicant): Committed to improving the health and well-being of mothers and their families, Duke Maternal-Fetal Medicine (MFM) is dedicated to continued participation in the NICHD Maternal-Fetal Medicine Units Network (MFMU). Duke MFM is well-suited to continue as an MFMU site given our research infrastructure, successful track record in basic and translational research, and patient volume. With 4 primary research faculty and 15 research staff, Duke MFM has a highly functional research team with over 20 years of experience in single and multi-center studies. Content expertise includes prematurity, premature rupture of membranes, fetal growth restriction, dysfunctional labor, maternal immunization, and maternal medical conditions. Technical expertise includes study design, recruitment and retention, molecular biology, data safety monitoring, coordinating and analysis, and decision/cost-effectiveness modeling. With 14 faculty, 6 fellows, 7 midwives, and 3 nurse practitioners, Duke MFM provides full service high-risk prenatal care and delivery, prenatal diagnosis, and consultative services for the Duke University Health System (DUHS). As a MFMU site since 2011, Duke MFM has served on administrative working groups and committees, protocol subcommittees, and submitted ancillary and secondary analyses. We have further strengthened our existing relationships with obstetricians in the community to successfully prioritize and enroll participants into MFMU trials and will continue to recruit participants from ~5,800 annual births across two DUHS institutions in Durham, North Carolina - Duke University Medical Center (~3,375) and Duke Regional Hospital (DRH) (~2,425). High risk conditions like hypertension, diabetes, asthma, multi-fetal gestation, prematurity, and low birthweight occur among half of all births across DUHS. Duke MFM has a highly productive and collegial relationship with Neonatology, providing continued expertise and support for their participation in the NICHD Neonatal Research Network and vice versa. Further, we have active partnerships across the Duke University campus including neonatology, pediatrics, infectious diseases, immunology, nursing, pathology, genetics, pharmacology, epidemiology, research pharmacies and the Duke Translational Medicine Institute (NIH CTSA), which can aid our success in the MFMU. Duke MFM is committed to working cooperatively with NICHD and the MFMU and has the expertise, resources, and institutional support to be a productive and successful site involved in multicenter collaborative research involving perinatal health.

 描述（由适用提供）：致力于改善母亲及其家人的健康和福祉，杜克大学母亲医学（MFM）致力于继续参与NICHD母体 - 富特医学单位网络（MFMU）。鉴于我们的研究基础设施，基础和翻译研究中的成功记录以及患者量，公爵MFM非常适合作为MFMU站点。 MFM拥有4位主要研究教师和15名研究人员，拥有一个高度功能的研究团队，在单一和多中心研究方面拥有超过20年的经验。内容专业知识包括早产，机制过早破裂，胎儿生长限制，功能失调的劳动力，产妇免疫抑制和孕产妇医疗状况。技术专长包括研究设计，招聘和保留，分子生物学，数据安全监测，协调和分析以及决策/成本效益建模。 Duke MFM拥有14名教职员工，6名研究员，7名助产士和3名护士从业人员，为杜克大学卫生系统（DUHS）提供全面服务的高风险产前护理和交付，产前诊断和咨询服务。自2011年以来，作为MFMU站点，MFM曾在行政工作组和委员会，协议小组委员会以及提交辅助和次要分析中任职。我们进一步加强了与社区中的产科医生的现有关系，以成功地将参与者纳入MFMU试验，并将继续从北卡罗来纳州达勒姆市的两个DUHS机构 - 杜克大学医学中心（约3,375）和杜克地区医院（drh）（DRH）（〜2,425）（〜2,425）中继续招募约5,800个年龄的参与者。高风险状况如高血压，糖尿病，哮喘，多野性妊娠​​，早产和低出生体重，在所有DUH的一半出生中发生。 MFM杜克大学与新生儿学有高度生产和合作关系，为他们参与NICHD新生儿研究网络提供了持续的专业知识和支持，反之亦然。此外，我们在整个杜克大学校园内建立了积极的伙伴关系，包括新生儿学，儿科，传染病，免疫学，护士，病理学，遗传学，药理学，药理学，流行病学，研究药店和杜克翻译医学研究所（NIH CTSA），这有助于我们在MFMU中的成功。 MFM杜克大学致力于与NICHD和MFMU合作，并拥有专业知识，资源和机构支持，成为一个涉及围产期健康的多中心协作研究的富有成效且成功的网站。