6/6 Planning for the HEALthy Early Development Study

6/6 规划健康早期发育研究

基本信息

批准号：
9899070
负责人：
Ludmila Nicole Bakhireva
金额：
$ 27.12万
依托单位：
UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-30 至 2022-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9899070
关键词：
Address Adolescence Adolescent Age Alcohol or Other Drugs use Alcohols Area Attention Behavioral Biological Markers Brain Cannabis Child Child Development Childhood Cognitive Cohort Studies Collaborations Collection Complex Data Development Emotional Environment Environmental Exposure Epidemic Ethics Exposure to Funding Future Goals Growth Growth and Development function Human Human Development Individual Infant Institution Leadership Legal Life Link Longitudinal cohort study Measurement Measures Mental disorders Methods National Institute of Drug Abuse Opioid Outcome Performance Phase Pregnancy Prospective cohort study Protocols documentation Recommendation Research Research Design Research Personnel Risk Sample Size Sampling Site Structure Techniques Testing Time Tobacco United States National Institutes of Health Vulnerable Populations Woman Work cognitive development critical period design early childhood evidence base experience fetal opioid exposure infancy innovation innovative technologies meetings middle childhood neurobehavioral neuroimaging new technology phase 2 study postnatal prenatal prospective recruit research study retention rate social synergism tool treatment strategy uptake working group

项目摘要

The Planning for the HEALthy Early Development Study will contribute to the design and recommended protocol for a future large-scale, multi-site research study to prospectively examine human brain, cognitive, behavioral, social and emotional development of children beginning prenatally through ages 9-10, and to determine the impact of maternal pre- and postnatal substance use on short- and long-term development of children. The Planning Study will link investigators across 6 research sites who have complementary experience and expertise in the areas that are essential to designing the study. Planning activities will be accomplished using a coordinated set of 10 Working Groups who will work collaboratively to design a sampling and recruitment strategy for a future large-scale study, to identify and recommend strategies for addressing the challenges to ethical recruitment and retention of vulnerable populations, and to develop and test a common protocol for neuroimaging, infant and child assessments, exposure assessment, biospecimen collection, and integration of novel technologies. By the end of the Planning Phase, the 6 Consortium sites will have produced and tested a recommended protocol for the future multi-site study, and will have established feasibility of carrying out the study protocol at each of the 6 linked sites.

健康的早期发展研究的计划将有助于设计和推荐的协议，用于未来的大规模多站点研究，以前瞻性检查开始的儿童的人脑，认知，行为，社会和情感发展产前至9-10岁，并确定产后和产后的影响儿童短期和长期发育的物质使用。计划研究将链接在6个研究网站的研究人员，他们具有互补的经验和专业知识对于设计研究至关重要的领域。计划活动将使用协调组的10个工作组，他们将合作设计抽样和未来大规模研究的招聘策略，以识别并推荐策略解决弱势群体的道德招聘和保留挑战，并开发和测试神经影像，婴儿和儿童评估，暴露的共同方案新技术的评估，生物测量收集和整合。到结束计划阶段，6个财团站点将生成并测试了推荐的协议对于未来的多站点研究，并将确定执行研究方案的可行性在6个链接站点中的每个。