Preventing Prescription Stimulant Diversion and Medication Misuse Via a Web-Based Simulation Intervention
通过基于网络的模拟干预防止处方兴奋剂转移和药物滥用
基本信息
- 批准号:9895462
- 负责人:
- 金额:$ 24.49万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-07-15 至 2023-05-31
- 项目状态:已结题
- 来源:
- 关键词:Academic achievementAccidental InjuryAcquaintancesAdderallAddressAdultAdvanced Practice NurseAlcohol or Other Drugs useAreaAttention deficit hyperactivity disorderAwarenessBehaviorBehavioralBenzodiazepinesCardiovascular systemCommunicationComputer SimulationComputersConsumptionCounselingDevelopmentDoseDrug PrescriptionsEmergency department visitEvidence based interventionExposure toFeedbackFriendsGoalsHeadacheHealthHealth PersonnelHealthcareHuman ResourcesInjuryInsurance CarriersInterventionKnowledgeLeadLearningMedicalMental HealthMoodsMorbidity - disease rateNational Institute of Drug AbuseOnline SystemsOpioidParticipantPerceptionPharmaceutical PreparationsPhysiologicalPlacebosPlanning TheoryPrevalencePrevention strategyPreventive InterventionPrivatizationProviderPsychiatristRandomized Controlled TrialsReportingResearchResistanceRiskRisk FactorsRouteSelf EfficacySiteSleeplessnessStrategic PlanningStudentsSubstance Use DisorderSymptomsTestingTimeaddictionbasebehavior changecollegeconduct problemcostcost effectivedisabilitydrug misuseeffective interventionemerging adultepidemiology studyevidence basefollow-uphigh riskillicit drug useinnovationinnovative technologiesintervention effectintervention participantsmedication compliancemedication nonadherencemisuse of prescription only drugsnonmedical usepediatricianpeerpreventprimary outcomepsychologicpsychological outcomesrandomized controlled designresponsesatisfactionsecondary outcomesexside effectsimulationskill acquisitionskillssocial cognitive theorystimulant misusestimulant usesymptom managementtherapy designuniversity studentvehicular accidentvirtual coachvirtual human
项目摘要
PROJECT SUMMARY
College students misuse and divert (i.e., give away, sell, or trade) prescription stimulants more often than any
other class of prescription drugs (e.g., opiates). Half or nearly half of college students with prescriptions divert
their stimulant medication, and a similarly high percentage misuse their medication (e.g., higher doses, via
different routes of administration, etc.) or use someone else’s prescription. Diversion may lead students to go
without needed medication to mitigate their symptoms, increasing their risk for unintentional injuries and
substance use. Further, diversion perpetuates the non-medical use of prescription stimulants (NMUPS), which
has become increasingly common among college students and is associated with other illicit drug use, lower
grade point average, insomnia, irritability, headaches, and cardiovascular complications. Diversion also
perpetuates medical misuse of stimulants among students with prescriptions, which is associated with poorer
ADHD symptom management and may increase the risk for addictive disorders. Despite the fact that nearly
9 out of 10 students obtain prescription stimulants from a friend or acquaintance with a prescription,
there are no evidence-based interventions targeting diversion of stimulants in college students. Being
approached for one’s medication is a key risk factor for diversion, as is medication non-adherence and
believing NMUPS and diversion are more prevalent than they are. Accordingly, in this multi-site study, we will
conduct a randomized, controlled trial of 300 college-attending adults with current stimulant prescriptions to
examine the preliminary efficacy and feasibility of a single-session, computer-based simulation intervention
(with two booster sessions) to prevent prescription stimulant diversion and medication misuse and compare it
to a placebo condition. Our intervention, which is grounded in social learning theory, the theory of planned
behavior, and our preliminary research, uniquely engages students in interactive discussions with virtual
humans to (a) learn about the actual prevalence of NMUPS and diversion and their related risks, (b) practice
using refusal strategies when approached for their medication in high-risk situations, and (c) understand how to
effectively communicate with prescribers and avoid medication misuse. Our primary aims are to determine if
the intervention reduces diversion, intentions to divert, and medication misuse, and to assess user satisfaction
with the intervention. Our secondary aims are to examine change in potential mechanisms of action targeted in
the intervention, such as self-efficacy to resist diversion, knowledge about diversion and NMUPS, use of
behavioral strategies to resist requests for one’s medication, and prescriber communication. Our study
responds to PA-17-775, which calls for pilot testing of innovative technology for disseminating effective
preventive interventions. It also aligns with NIDA’s Strategic Plan, which encourages the development of
preventive interventions that target risk factors for substance use disorders. If effective, the intervention could
be readily and widely disseminated to college counseling centers, psychiatrists/APRNs, and pediatricians.
项目摘要
大学生滥用和转移(即放弃,出售或交易)处方兴奋剂比任何人都要多
其他类别的处方药(例如操作学)。有处方的大学生的一半或一半
它们的刺激性药物和类似的高百分比会错过药物(例如,较高剂量,通过
不同的管理途径等)或使用别人的处方。转移可能会导致学生走
无需药物来减轻症状,增加其无意伤害的风险和
使用物质。此外,转移使处方兴奋剂(NMUP)的非医学使用永久使用,该使用
在大学生中已经变得越来越普遍,并且与其他非法药物使用相关,较低
平均成绩,失眠,烦躁,标头和心血管并发症。也转移
在有处方的学生中延续了对兴奋剂的医学失误,这与较差有关
多动症症状管理,可能会增加累加症的风险。尽管事实几乎
十分之一的学生中有9名从朋友那里获得处方兴奋剂或以处方的方式收购,
没有针对大学生兴奋剂转移的循证干预措施。存在
接受药物治疗是转移的关键危险因素,药物不遵守和
相信NMUP和转移比它们更普遍。根据这项多站点研究,我们将
对300名具有当前兴奋性处方的成年人进行随机对照试验
检查单节,基于计算机的模拟干预的初步效率和可行性
(有两个助推器会议)防止处方刺激性转移和药物失误并进行比较
达到安慰剂条件。我们的干预措施是基于社会学习理论,是计划的理论
行为和我们的初步研究,独特地吸引了学生与虚拟的互动讨论
人类(a)了解NMUP和转移及其相关风险的实际患病率,(b)实践
在高风险情况下使用拒绝策略时,使用拒绝策略,(c)了解如何
有效地与处方者沟通并避免滥用药物。我们的主要目的是确定是否是否
干预措施减少了转移,转移和药物的意图,并评估用户满意度
进行干预。我们的次要目的是检查针对目标的潜在作用机理的变化
干预措施(例如自我效力抵抗转移,都知道转移和nmups)的使用
行为策略,以抵制对药物的要求和处方者的沟通。我们的研究
响应PA-17-775,它呼吁对创新技术进行试点测试以发射有效
预防性干预措施。它还与NIDA的战略计划保持一致,这鼓励了
针对物质使用障碍的危险因素的预防干预措施。如果有效,干预可以
容易被广泛传播到大学咨询中心,精神科医生/APRN和儿科医生。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Laura Holt其他文献
Laura Holt的其他文献
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{{ truncateString('Laura Holt', 18)}}的其他基金
Preventing Prescription Stimulant Diversion and Medication Misuse Via a Web-Based Simulation Intervention
通过基于网络的模拟干预防止处方兴奋剂转移和药物滥用
- 批准号:
10212996 - 财政年份:2020
- 资助金额:
$ 24.49万 - 项目类别:
Preventing Prescription Stimulant Diversion and Medication Misuse Via a Web-Based Simulation Intervention
通过基于网络的模拟干预防止处方兴奋剂转移和药物滥用
- 批准号:
10404680 - 财政年份:2020
- 资助金额:
$ 24.49万 - 项目类别:
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