Promoting Lifestyle Change via Tailored mHealth To Improve Health, HL131583

通过定制移动医疗促进生活方式改变以改善健康，HL131583

• 批准号: 9763184
• 负责人: LORA Emilie BURKE
• 金额: $ 5.6万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9763184
• 关键词: Address; Adherence; Adult; Algorithms; Behavior; Behavior Therapy; Bluetooth; Body Weight decreased; Calories; Cardiovascular Diseases; Cellular Phone; Chronic; Data; Development; Devices; Diabetes Mellitus; Diet; Diet Monitoring; Dietary intake; Eating; Fatty acid glycerol esters; Feasibility Studies; Feedback; Frequencies; Goals; Habits; Health; Hour; Individual; Instruction; Intake; Intervention; Investigation; Life Style; Link; Measures; Monitor; Motivation; Obesity; Outcome; Paper; Participant; Pattern; Performance; Persons; Physical activity; Population; Protocols documentation; Psychological reinforcement; Public Health; Randomized; Randomized Clinical Trials; Research; Self-Direction; Structure; System; Technology; Testing; Time; Translating; Treatment Protocols; Weight; Weight maintenance regimen; adult obesity; base; behavior change; cardiovascular risk factor; cost; diaries; evidence base; fitbit; improved; individualized feedback; innovation; intelligent personal assistant; mHealth; mobile computing; novel; programs; smartphone Application; tailored messaging; tool; treatment program; weight loss intervention; weight loss program

ABSTRACT Our investigative team has been studying the intricacies of self-monitoring for over a decade and has documented that consistency and timing of self-monitoring in relation to eating is significantly related to weight loss outcomes. More recently, evidence is building to support adding feedback (FB) messages to self- monitoring for reinforcing behavior change and enhancing motivation and adherence. Empirical evidence demonstrates that the more proximal the reinforcing message is delivered following the performance of the desired behavior, the more likely it will increase the desired behavior. The proposed study is based on this body of evidence, in part provided by a previous trial conducted by our team and promising pilot data of the proposed intervention. Subjects in the previous weight loss trial were more adherent to self-monitoring and the treatment protocol and more likely to achieve 5% weight loss if they received a once-daily FB message tailored to what they had recorded that day than those who did not receive FB. Building on this study, we have developed an extensive FB algorithm with more than 1000 conditions to address diet and physical activity. Given our findings from our past research on self-monitoring in weight loss and the results of our pilot feasibility study testing the FB in conjunction with SM, we propose to conduct a full-scale, 4-year RCT where 530 adults will be randomized 1:1 to either: 1) self-monitoring (SM), where subjects will self-monitor diet, physical activity and weight using a commercially available self-monitoring application; or 2) SM+FB, where participants self- monitor and receive real-time FB messages. The group with FB will receive up to 4 daily pop-up FB messages on their smartphone delivered randomly during waking hours and tailored to entries in the subjects’ smartphone-based diaries. The primary specific aims for this study are to: 1) determine if SM with tailored FB delivered in real time up to 4 times per day is superior for promoting weight loss at 6 and 12 months to the SM condition and 2) Compare sustainability of engagement between the SM and the SM+FB groups for the full 12- mo study as measured by adherence to components of study protocol at 3, 6, 9 and 12 mos. We will also conduct innovative analyses to explore the temporal relationships of the frequency, timing and type of FB delivered and subsequent lifestyle behaviors through examination of serially collected real-time SM data. The proposed research addresses a major public health problem and is innovative in its large scale testing of a novel FB algorithm and program to reinforce healthful behaviors and its examination of the sustainability of engagement. If proven efficacious, this intervention could be efficiently translated and through integration with commercial apps could be fully scalable and disseminated to reach large numbers of individuals who wish to improve their health with lower in cost than existing programs.

抽象的 我们的调查团队一直在研究自我监控的复杂性已有十多年了，并且 记录到，与饮食有关的自我监控的一致性和时间与体重显着相关 损失结果。最近，证据正在建立支持向自我添加反馈（FB）消息 监视加强行为改变并增强动力和依从性。经验证据 证明在性能之后，加强消息的近端近端 所需的行为，它越有可能增加所需的行为。拟议的研究基于此 证据机构，部分是由我们的团队先前进行的试验和有希望的飞行员数据提供的 拟议的干预措施。以前的减肥试验中的受试者更加遵守自我监控和 治疗方案，如果收到每日一次的FB消息，他们更有可能实现5％的体重减轻 比那些没有收到FB的人所记录的东西。在这项研究的基础上，我们有 开发了一种广泛的FB算法，具有1000多种条件来解决饮食和体育锻炼。 鉴于我们过去关于减肥自我监控以及飞行员可行性结果的发现 研究测试FB与SM结合的研究，我们建议进行全面的4年RCT，其中有530名成年人 将被随机分配1：1至：1）自我监控（SM），受试者将自我监控，体育锻炼 并使用市售的自我监控应用程序的重量；或2）SM+FB，参与者自我自我 监视并接收实时FB消息。 FB的小组将收到多达4个每日弹出式FB消息 在他们的智能手机上随机交付，并根据受试者的条目量身定制 基于智能手机的日记。这项研究的主要特定目的是：1）确定SM是否具有量身定制的FB 每天最多可实时交付4次，对于在6和12个月时促进体重减轻至SM是优越的 条件和2）比较SM与SM+FB组之间参与的可持续性，以进行全部12-- MO研究通过遵守3、6、9和12 MOS研究方案的组成部分进行衡量。我们也会 进行创新分析以探索FB频率，时机和类型的临时关系 通过检查串行收集的实时SM数据来交付和随后的生活方式行为。 拟议的研究解决了一个重大的公共卫生问题，并且在其大规模测试中具有创新性 一种新颖的FB算法和计划，以增强健康行为及其对可持续性的研究 订婚。如果有效地有效，则可以有效地翻译此干预措施 商业应用程序可能是完全可扩展的，并且可以传播，以吸引大量希望 与现有计划相比，成本更低的成本提高健康状况。