Pollutant Responses in Marine Organisms (PRIMO 20)

海洋生物中的污染物反应 (PRIMO 20)

• 批准号: 9760885
• 负责人: Richard Di Giulio
• 金额: $ 1.5万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-15 至 2020-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9760885
• 关键词: Address; Area; Biological Markers; Boston; Chemicals; Comparative Biology; Development; Disease; Endocrine disruption; Environment; Exposure to; Fees; Fostering; Fresh Water; Funding; Government; Graduate Education; Health; Human; Individual; Interdisciplinary Study; Letters; Location; Marines; Metals; Molecular; National Institute of Environmental Health Sciences; North Carolina; Oceans; Organism; Participant; Pesticides; Play; Research; Research Personnel; Science; Scientific Societies; Scientist; Students; Superfund; Time; Toxic effect; Translational Research; Travel; Universities; Washington; Wood material; Xenobiotic Metabolism; aquatic organism; cost; falls; genotoxicity; graduate student; human model; marine organism; meetings; nanomaterials; pollutant; programs; receptor-mediated signaling; response; stressor; symposium

This will be the Pollutant Responses in Marine Organisms (PRIMO 20) 20th annual conference which meets every other year at various locations world-wide. PRIMO 20 will be the first meeting in the U.S. since 2011, held in Long Beach, CA. This very prestigious meeting brings together top scientists and their students from around the world who investigate the impacts of chemical pollutants on marine and freshwater organisms. A major thrust historically and currently is the elucidation of underlying molecular mechanisms of toxicity. This thrust extends the relevance of the meeting from impacts in marine/aquatic environments to human health, and thus to NIEHS. PRIMO has also had particular relevance to the Superfund Research Program (SRP). The symposium will include sessions addressing mechanisms and impacts of POPs, metals, pesticides, nanomaterials, microplastics and other ubiquitous pollutants, many of which fall under the purview of the SRP. Additionally, the science emphasized includes endocrine disruption, xenobiotic metabolism, `omic approaches, genotoxicity, effects on development and transgenerational impacts, receptor-mediated signaling, and biomarkers of exposure and effect. Many Superfund Program investigators have been and continue to be highly involved in PRIMO meetings. One of PRIMO's co-founders is Dr. John Stegeman, a long-time investigator with the Boston University Superfund Research Center (see letter of support). Other SRP investigators that are regular participants in PRIMO meetings include Evan Gallagher (University of Washington), Mark Hahn (Woods Hole/Boston University), Dan Schlenk (UC Riverside), Seth Kullman (North Carolina State University), and David Hinton and Richard Di Giulio (Duke University). Several of these individuals are playing key roles in the planning for PRIMO 20. PRIMO is not affiliated with any scientific society. The meetings are funded by registration fees and modest support from a few relevant companies, government (SRP via the R13 mechanism has provided support for past meetings in the U.S.), and universities. Support beyond registration fees is used to support travel costs for graduate students.

这将是海洋生物的污染物反应（Primo 20）第20届年会 每隔一年在全球各个地点开会一次。 Primo 20将是第一个 自2011年以来在美国举行的会议，在加利福尼亚州长滩举行。这次享有声望的会议带来了 共同研究世界各地的高级科学家及其学生 海洋和淡水生物的化学污染物。历史上的主要推力 目前是阐明潜在的毒性分子机制。这个推力延伸 会议从海洋/水生环境的影响到人类健康的相关性， 因此对尼斯。 Primo还与超级基金研究计划（SRP）特别相关。这 研讨会将包括涉及流行音乐，金属的影响和影响的会议 农药，纳米材料，微塑料和其他普遍存在的污染物，其中许多降低 在SRP的权限下。此外，强调的科学包括内分泌 破坏，异种新陈代谢，`omic方法，遗传毒性，对发展和影响的影响 跨代影响，受体介导的信号传导以及暴露和效应的生物标志物。 许多超级基金计划调查人员已经并且继续高度参与Primo 会议。 Primo的联合创始人之一是John Stegeman博士，他是一名长期调查员 波士顿大学超级基金研究中心（请参阅支持信）。其他SRP调查人员 Primo会议的常规参与者包括Evan Gallagher（大学 华盛顿），马克·哈恩（Mark Hahn）（伍兹·霍尔（Woods Hole）/波士顿大学），丹·施伦克（UC Riverside），塞思 库尔曼（北卡罗来纳州立大学），戴维·辛顿（David Hinton）和理查德·迪·吉利奥（Richard Di Giulio）（杜克大学 大学）。这些人中有几个在Primo 20的计划中扮演关键角色。 Primo与任何科学社会都不隶属。会议由注册费资助 政府（通过R13机制SRP）得到了一些相关公司的适度支持 已经为美国和大学提供了过去的支持。超越支持 注册费用于支持研究生的旅行费用。