Pancreatic Diseases Gordon Research Conference

胰腺疾病戈登研究会议

基本信息

批准号：
9756743
负责人：
Maike Sander
金额：
$ 2.5万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-03-01 至 2020-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9756743
关键词：
Acinar Cell Address Basic Science Biological Biological Assay Biology Cells Clinical Clinical Research Collaborations Communication Communities Development Diabetes Mellitus Digestion Discipline Disease Ductal Epithelial Cell Duodenum Endocrine Endocrinologist Environment Enzymes Exocrine pancreas Food Fostering Gastroenterologist Gland Glucagon Glucose Goals Health Homeostasis Hormones Human Human body Image Impairment Insulin Interdisciplinary Study International Islet Cell Islets of Langerhans Jordan Lead Life Link Maintenance Malignant - descriptor Malignant Neoplasms Malignant neoplasm of pancreas Medical Mentorship Metabolic Modeling Molecular Mus Natural regeneration Organ Organoids Pancreas Pancreatic Adenocarcinoma Pancreatic Diseases Pancreatitis Pharmacology Positioning Attribute Postdoctoral Fellow Process Production Research Research Personnel Resolution Risk Factors Rivers Scientist Somatostatin Structure of beta Cell of islet Surgeon Therapeutic Time Training Translational Research Work base career cell behavior cell type chronic pancreatitis doctoral student epidemiology study experience human disease human model insight interdisciplinary approach interest novel novel strategies pancreas development pancreatic cancer patients pancreatic juice peer posters programs recruit response success symposium tool translational approach

项目摘要

PROJECT SUMMARY/ABSTRACT Recent years have brought rapid advances in our understanding of the molecular mechanisms involved in pancreatic development, regeneration, and malignant transformation, as well as our ability to model these processes in mice and recently also human cells. These studies have revealed lineage relationships between the different pancreatic cell types and plasticity in response to environmental influences. At the clinical level, epidemiological studies show a clear association between pancreatic diseases, in particular between diabetes and pancreatic cancer. Yet, the mechanisms that underlie the co-occurrence of pancreatic diseases are poorly understood. This relatively new GRC aims to link the understanding of the biology of the exocrine and endocrine pancreas to applications for human diseases. This GCR is unique in that it is the only conference that convenes experts from all aspects of pancreas biology as well as clinicians working on translational approaches for diabetes, pancreatic cancer and pancreatitis. By providing a forum for the presentation and discussion of cutting edge, unpublished concepts and approaches, the goal of this GRC is to stimulate discussion across fields and disciplines. This exchange will foster interdisciplinary approaches in the field and promote exchange of ideas and experiences to lead to new collaborations, as well as empower young scientists to showcase their work to peers and leaders in the field. Following the success of the previous conferences, the fourth GRC "Pancreatic Diseases" will take place at the Jordan Hotel, Sunday River, ME, USA from June 16 - 21, 2019. The conference will focus on understanding cell behavior and environmental influences in pancreatic diseases with the goal of gaining insights into how the systemic and local environment impacts the state of endocrine and exocrine cells in health and disease. The program that has been assembled is first-rate, benefitting from the contribution of international world-class scientists engaged in research relevant to different aspects of pancreatic diseases. The ultimate goal of the conference is the identification of novel concepts in pancreatic diseases that might be exploitable for pharmacological and cell-based therapeutic approaches. As for all GRCs, the guiding principle of this conference is the presentation of new, unpublished results and the free, unhampered discussion that follows. Participation of young scientists, including PhD students, postdocs and junior group leaders is especially emphasized, with opportunities of short talks and poster presentations.

项目概要/摘要近年来，我们对相关分子机制的理解取得了快速进展。胰腺发育、再生和恶性转化，以及我们模拟这些的能力小鼠和最近的人类细胞中的过程。这些研究揭示了三者之间的血统关系不同的胰腺细胞类型和可塑性对环境影响的反应。在临床层面，流行病学研究表明胰腺疾病之间存在明显关联，特别是糖尿病之间和胰腺癌。然而，胰腺疾病同时发生的机制尚不清楚。明白了。这个相对较新的 GRC 旨在将外分泌和内分泌生物学的理解联系起来胰腺在人类疾病中的应用。这次 GCR 的独特之处在于它是唯一召开的会议来自胰腺生物学各个方面的专家以及致力于转化方法的临床医生糖尿病、胰腺癌和胰腺炎。通过提供一个展示和讨论切割的论坛边缘、未发表的概念和方法，本次 GRC 的目标是激发跨领域和跨领域的讨论学科。此次交流将促进该领域的跨学科方法并促进思想交流和经验来促成新的合作，并赋予年轻科学家展示他们的工作的能力该领域的同行和领导者。继前几届会议取得成功之后，第四届 GRC“胰腺疾病”将于 2019 年 6 月 16 日至 21 日在美国缅因州周日河约旦酒店举行。会议将重点关注了解细胞胰腺疾病中的行为和环境影响，目的是深入了解胰腺疾病如何全身和局部环境影响健康和疾病中内分泌和外分泌细胞的状态。这汇集的节目是一流的，得益于国际一流的贡献科学家们从事与胰腺疾病不同方面相关的研究。该项目的最终目标是会议旨在确定胰腺疾病的新概念，这些概念可用于药理学和基于细胞的治疗方法。对于所有GRC来说，本次会议的指导原则是对新的、未发表的结果的介绍以及随后的自由、不受阻碍的讨论。参与特别强调青年科学家，包括博士生、博士后和初级组长，简短演讲和海报展示的机会。