UCSD Cancer Center Training Program in Drug Development

加州大学圣地亚哥分校癌症中心药物开发培训项目

• 批准号: 9308867
• 负责人: STEPHEN B HOWELL
• 金额: $ 53.29万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9308867
• 关键词: Cancer Center; Training Programs; drug development

7. PROJECT SUMMARY/ABSTRACT This renewal application seeks funding to continue the highly successful Cancer Therapeutics Training (CT2) Program at the Moores Comprehensive Cancer Center at the University of California, San Diego. The mission of the CT2 program is to train the PhD and physician-scientists who will become the next generation of leaders in the field of cancer therapeutics and diagnostics in each of the major steps required for successful translation of laboratory-based discoveries into safe and effective therapeutic agents and diagnostic modalities. The CT2 training is designed to position trainees to play key leadership roles in the field of oncology therapeutics. The 27 faculty of the CT2 Program are all Members of the Cancer Center and are based in 10 departments in the School of Medicine, the Scripps Institute of Oceanography or the general campus. Each faculty mentor is an accomplished investigator and educator with a history of training superb post-doctoral fellows. Each has substantial peer-reviewed cancer or cancer-related research funding. All of the participating faculty are conducting translational research and have been selected because of their interest in new cancer therapeutics. This program is extensively integrated into the other cancer related activities of the Cancer Center and of UCSD. The goal is to recruit and retain 8 MD and PhD scientists in this two-year program that will position them for careers in the development of new cancer drugs or the diagnostics needed to guide the use of these drugs in the era of personalized medicine. The training program has 3 components: 1) the completion of formal didactic teaching sessions that cover tools essential to the drug development process; 2) the conduct of a drug or diagnostic development research project under the direction of a faculty mentor; and, 3) required participation in the annual meeting of the American Association for Cancer Research or an equivalent national drug development meeting. Trainees are also expected to participate in Cancer Center and Departmental seminars, research rounds and journal clubs to expand the breadth of their understanding of cancer research, and prepare formal project plans and practice or real grant applications for review by the Executive Committee. Methods are in place to ensure that all trainees are properly instructed in the principles of responsible conduct of research and scientific integrity. Trainees are recruited nationwide and special efforts are made recruit and retain exceptional minority, women and disadvantaged candidates. During its first 10 years of operation the CT2 Program has drawn trainees from major research universities across the country as well as from the Gradate Biomedical Sciences and Surgery, Hematology/Oncology, and Pediatric clinical training programs. This Program has been so successful that the Cancer Center has established a parallel program of additional fellowships in cancer therapeutics funded by donations.

7。项目摘要/摘要 该更新应用程序寻求资金继续进行非常成功的癌症治疗培训（CT2） 在加利福尼亚大学圣地亚哥分校的摩尔综合癌症中心计划。任务 CT2计划是培训将成为下一代领导者的博士学位和医师科学家 在成功翻译所需的每个主要步骤中，在癌症治疗和诊断领域 将基于实验室的发现融入安全有效的治疗剂和诊断方式。 CT2 培训旨在定位受训者，以在肿瘤学治疗领域中扮演关键的领导角色。这 27 CT2计划的教职员工都是癌症中心的成员，位于10个部门 医学院，斯克里普斯海洋学研究所或一般校园。每个教师导师都是 有成就的调查员和教育家，拥有培训精湛的博士后研究员的历史。每个都有 大量同行评审的癌症或与癌症有关的研究资金。所有参与的教师都是 进行翻译研究并因其对新的癌症治疗剂的兴趣而被选中。 该程序已广泛整合到癌症中心和癌症中心的其他相关活动中 UCSD。目标是在这个为期两年的计划中招募和保留8个MD和博士学位科学家 它们是从事新癌症药物或指导使用所需的诊断的职业 个性化医学时代的药物。培训计划有3个组成部分：1） 正式的教学教学课程，涵盖对药物开发过程至关重要的工具； 2）行为 在教师导师的指导下，药物或诊断开发研究项目； 3）需要 参加美国癌症研究协会或同等国家的年度会议 药物开发会议。预计学员还将参加癌症​​中心和部门 研讨会，研究回合和期刊俱乐部，以扩大他们对癌症研究的理解的广度， 并准备执行委员会的正式项目计划和实践或实际赠款申请进行审查。 采用方法来确保所有受训人员都得到负责任的原则的正确指导 研究与科学完整性。在全国范围内招募了学员，并进行了特殊努力，并 保留杰出的少数民族，妇女和处境不利的候选人。在运营的头十年中 CT2计划吸引了来自全国各地的主要研究学院的学员 评级生物医学科学和手术，血液学/肿瘤学和儿科临床培训计划。 该计划非常成功，以至于癌症中心已经建立了一个并行计划 由捐赠资助的癌症治疗学奖学金。