Integrating Addiction Research in Health Systems: The Addiction Research Network

将成瘾研究纳入卫生系统：成瘾研究网络

基本信息

批准号：
9471734
负责人：
KATHARINE ANTHONY BRADLEY
金额：
$ 200.29万
依托单位：
KAISER FOUNDATION RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-01 至 2020-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9471734
关键词：
Accident and Emergency department Address Adolescent Adult Age Alcohol or Other Drugs use Behavior Therapy Biometry Calibration Cancer Research Network Caring Childhood Chronic Disease Clinical Clinical Trials Network Comorbidity Data Development Diabetes Mellitus Economics Electronic Health Record Ensure Family Policy Foundations Future Geography Goals Health Health Care Reform Health Services Research Health system Healthcare Healthcare Systems Hypertension Influentials International Lead Learning Measures Medical Mental Health Minority Monitor Operative Surgical Procedures Outcome Outcomes Research Patient Monitoring Patient-Centered Care Patient-Focused Outcomes Patients Pharmaceutical Preparations Policies Population Population Study Pragmatic clinical trial Primary Health Care Privatization Public Health Quality of Care Randomized Controlled Trials Reporting Research Research Design Research Infrastructure Research Methodology Research Personnel Services Severities Substance Use Disorder System Testing Time United States United States National Institutes of Health Variant Vision Work Youth addiction alcohol misuse clinical care comparative effectiveness design eHealth effective intervention effective therapy effectiveness research ethnic diversity evidence base experience health care delivery implementation research improved improved outcome innovation learning network medical specialties opioid misuse patient oriented patient registry population based pragmatic trial programs public health relevance racial and ethnic screening social stigma study population virtual young adult

项目摘要

DESCRIPTION: Over 20 million US adults and youth suffer from substance use disorders (SUDs) and substance use (SU) related problems. However, most people with SUDs never receive SUD treatment. Historically, research on SUDs has focused on the small minority of patients with SUDs who are seeking, or already engaged in, specialty SUD treatment. The overall goal of the proposed Addictions Research Network (ARN) node of the Clinical Trials Network will be to conduct cutting edge research to improve outcomes in all patients with SU/SUD who are seen in medical settings. The ARN includes 15 large health systems across the US that use the HMO Research Network's (HMORN's) Virtual Data Warehouse, providing geographic and racial/ethnic diversity as well as variation in systems of medical and SU/SUD care. The proposed ARN node has 3 broad agendas-1) to evaluate effective practices for identifying, engaging and treating patients with SU or SUDs in medical settings; 2) to develop and test effective, practical ways to implement these practices in a sustained manner as part of routine medical care; and 3) to develop and disseminate innovative research methods on SU and SUDs. Three PIs will lead the ARN node, each with expertise critical to our research agenda. Dr. Weisner, who has more than 25 years of experience leading SUD research in public and private medical settings, will lead the ARN as Senior PI at Kaiser Permanente. She partners at Kaiser Permanente with Dr. Campbell, an expert in research on opioid misuse and patient-centered and comparative effectiveness research, and Dr. Bradley, Senior PI at Group Health, who has 20 years of research experience targeting non-treatment-seeking patients with alcohol misuse and SUDs in medical settings. The ARN will have 3 Cores: 1) an Administrative Core will support all aspects of the ARN node; 2) an Implementation Core will support patient-centered design of practical, sustainable approaches to implementing SUD care in routine medical settings using electronic health records (EHRs), and; 3) an Analytics Core with expertise in programming, biostatistics using EHR data, and economics, will support innovative methods research and study design. ARN work will leverage the HMORN's 20 years of conducting pragmatic clinical trials and comparative effectiveness research across health systems using EHRs and the nationwide Virtual Data Warehouse. The ARN node will provide a robust foundation for population-based studies-including pragmatic randomized controlled trials, comparative effectiveness studies, and implementation research-that can evaluate long-term health outcomes. Moreover, through our connection to 15 learning healthcare systems, our research will design approaches to improve the quality of care for SU and SUDs in real-world medical settings. In this way-with the other CTN nodes-the ARN node will help build the infrastructure required for the next era of addictions health services research.

描述：超过2000万美国成年人和青年患有药物使用障碍（SUD）和药物使用（SU）相关问题。但是，大多数有SUD的人从未接受过SUD治疗。从历史上看，对SUDS的研究集中在寻求或已经从事专业SUD治疗的SUD患者中的少数患者。临床试验网络的拟议成瘾研究网络（ARN）节点的总体目标是进行尖端研究，以改善所有在医疗环境中看到的SU/SUD患者的结果。 ARN包括美国各地的15个大型卫生系统，使用HMO研究网络（HMORN）虚拟数据仓库，提供地理和种族/种族多样性以及医疗和SU/SU/SUD CARE系统的变化。拟议的ARN节点具有3个广泛的议程1），以评估在医疗环境中识别，参与和治疗SU或SUD患者的有效实践； 2）作为常规医疗服务的一部分，以持续的方式开发和测试有效的实用方法来实施这些实践； 3）开发和传播有关SU和SUDS的创新研究方法。三个PI将领导ARN节点，每个PI对我们的研究议程至关重要。 Weisner博士拥有超过25年的公共和私人医疗环境中SUD研究经验，将领导ARN在Kaiser Permanente担任高级PI。她在Kaiser Permanente的合作伙伴坎贝尔博士（Campbell）博士，坎贝尔博士（Campbell博士）是阿片类Missuse和以患者为中心和比较有效性研究的研究专家，以及Broup Health的高级PI Bradley博士，他在医疗环境中具有20年的研究经验，他们针对非治疗搜索饮酒和SUD的患者的研究经验。 ARN将有3个核心：1）管理核心将支持ARN节点的所有方面； 2）实施核心将支持以患者为中心的实用，可持续方法的设计，以使用电子健康记录（EHR）（EHR）在常规医疗环境中实施SUD护理，并且； 3）具有编程专业知识，使用EHR数据的生物统计学专业知识的分析核心将支持创新方法研究和研究设计。 ARN的工作将利用Hmorn使用EHR和全国性虚拟数据仓库在卫生系统之间进行务实的临床试验和比较有效性研究的20年。 ARN节点将为基于人群的研究提供稳健的基础，包括务实的随机对照试验，比较有效性研究和实施研究 - 可以评估长期健康结果。此外，通过与15个学习医疗系统的联系，我们的研究将设计方法，以提高现实世界中医疗环境中SU和SUD的护理质量。这样，其他CTN节点（ARN节点）将有助于建立下一个成瘾卫生服务研究时代所需的基础设施。