Integrating Addiction Research in Health Systems: The Addiction Research Network

将成瘾研究纳入卫生系统：成瘾研究网络

基本信息

批准号：
9276641
负责人：
KATHARINE ANTHONY BRADLEY
金额：
$ 73.64万
依托单位：
KAISER FOUNDATION RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-01 至 2020-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9276641
关键词：
Accident and Emergency department Address Adolescent Adult Age Alcohol or Other Drugs use Behavior Therapy Biometry Calibration Cancer Research Network Caring Childhood Chronic Disease Clinical Clinical Trials Network Comorbidity Data Development Diabetes Mellitus Economics Electronic Health Record Ensure Family Policy Foundations Future Geography Goals Health Health Care Reform Health Services Research Health system Healthcare Healthcare Systems Hypertension Influentials International Lead Learning Measures Medical Mental Health Minority Monitor Operative Surgical Procedures Outcome Outcomes Research Patient Monitoring Patient-Centered Care Patient-Focused Outcomes Patients Pharmaceutical Preparations Policies Population Population Study Pragmatic clinical trial Primary Health Care Privatization Public Health Quality of Care Randomized Controlled Trials Reporting Research Research Design Research Infrastructure Research Methodology Research Personnel Services Severities Substance Use Disorder System Testing Time United States United States National Institutes of Health Variant Vision Work Youth addiction alcohol misuse clinical care comparative effectiveness design eHealth effective intervention effective therapy effectiveness research ethnic diversity evidence base experience health care delivery implementation research improved improved outcome innovation learning network medical specialties opioid misuse patient oriented patient registry population based pragmatic trial programs public health relevance racial and ethnic screening social stigma study population virtual young adult

项目摘要

DESCRIPTION: Over 20 million US adults and youth suffer from substance use disorders (SUDs) and substance use (SU) related problems. However, most people with SUDs never receive SUD treatment. Historically, research on SUDs has focused on the small minority of patients with SUDs who are seeking, or already engaged in, specialty SUD treatment. The overall goal of the proposed Addictions Research Network (ARN) node of the Clinical Trials Network will be to conduct cutting edge research to improve outcomes in all patients with SU/SUD who are seen in medical settings. The ARN includes 15 large health systems across the US that use the HMO Research Network's (HMORN's) Virtual Data Warehouse, providing geographic and racial/ethnic diversity as well as variation in systems of medical and SU/SUD care. The proposed ARN node has 3 broad agendas-1) to evaluate effective practices for identifying, engaging and treating patients with SU or SUDs in medical settings; 2) to develop and test effective, practical ways to implement these practices in a sustained manner as part of routine medical care; and 3) to develop and disseminate innovative research methods on SU and SUDs. Three PIs will lead the ARN node, each with expertise critical to our research agenda. Dr. Weisner, who has more than 25 years of experience leading SUD research in public and private medical settings, will lead the ARN as Senior PI at Kaiser Permanente. She partners at Kaiser Permanente with Dr. Campbell, an expert in research on opioid misuse and patient-centered and comparative effectiveness research, and Dr. Bradley, Senior PI at Group Health, who has 20 years of research experience targeting non-treatment-seeking patients with alcohol misuse and SUDs in medical settings. The ARN will have 3 Cores: 1) an Administrative Core will support all aspects of the ARN node; 2) an Implementation Core will support patient-centered design of practical, sustainable approaches to implementing SUD care in routine medical settings using electronic health records (EHRs), and; 3) an Analytics Core with expertise in programming, biostatistics using EHR data, and economics, will support innovative methods research and study design. ARN work will leverage the HMORN's 20 years of conducting pragmatic clinical trials and comparative effectiveness research across health systems using EHRs and the nationwide Virtual Data Warehouse. The ARN node will provide a robust foundation for population-based studies-including pragmatic randomized controlled trials, comparative effectiveness studies, and implementation research-that can evaluate long-term health outcomes. Moreover, through our connection to 15 learning healthcare systems, our research will design approaches to improve the quality of care for SU and SUDs in real-world medical settings. In this way-with the other CTN nodes-the ARN node will help build the infrastructure required for the next era of addictions health services research.

描述：超过 2000 万美国成年人和青少年患有物质使用障碍 (SUD) 和物质使用 (SU) 相关问题，但大多数患有 SUD 的人从未接受过 SUD 治疗。正在寻求或已经从事特殊 SUD 治疗的 SUD 拟议的临床试验网络成瘾研究网络 (ARN) 节点的总体目标将是进行前沿研究，以改善所有患者的治疗结果。 ARN 包括美国各地使用 HMO 研究网络 (HMORN) 虚拟数据仓库的 15 个大型卫生系统，提供地理和种族/民族多样性以及医疗和卫生系统的差异。 SU/SUD 护理。拟议的 ARN 节点有 3 个广泛的议程 - 1) 评估在医疗环境中识别、参与和治疗 SU 或 SUD 患者的有效实践；2) 开发和测试有效、实用的实施方法；作为常规医疗护理的一部分，以持续的方式开展这些实践；3) 开发和传播有关 SU 和 SUD 的创新研究方法，三位 PI 将领导 ARN 节点，他们的专业知识对我们的研究议程至关重要。拥有超过 25 年在公共和私人医疗机构领导 SUD 研究的经验，将作为 Kaiser Permanente 的高级 PI 领导 ARN。她在 Kaiser Permanente 与阿片类药物研究专家 Campbell 博士合作。 Group Health 的高级 PI Bradley 博士拥有 20 年针对医疗环境中酒精滥用和 SUD 的非寻求治疗患者的研究经验，ARN 将有 3 个核心。： 1) 管理核心将支持 ARN 节点的所有方面； 2) 实施核心将支持以患者为中心的实用、可持续方法的设计，以使用电子健康记录 (EHR) 在常规医疗环境中实施 SUD 护理， 3) 具有编程、使用 EHR 数据的生物统计学和经济学方面的专业知识的分析核心将支持创新方法研究和研究设计，将利用 HMORN 20 年来在各个卫生系统中开展的务实临床试验和比较有效性研究。 EHR 和全国虚拟数据仓库将为基于人群的研究（包括实用随机对照试验、比较有效性研究和实施研究）提供坚实的基础，从而评估长期健康结果。通过与 15 个学习医疗保健系统的连接，我们的研究将设计方法来提高现实世界医疗环境中 SU 和 SUD 的护理质量，这样，ARN 节点将与其他 CTN 节点一起帮助构建所需的基础设施。为下一个时代的成瘾健康服务研究。