The Influence of PrEP Stigma among Black and Latino MSM PrEP Adopters

PrEP 耻辱对黑人和拉丁裔 MSM PrEP 采用者的影响

基本信息

批准号：
9266828
负责人：
Ronald Andrew Brooks
金额：
$ 15.65万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-04-26 至 2019-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9266828
关键词：
AIDS prevention AIDS/HIV problem Adherence Adopted Adoption Affect Anti-Retroviral Agents Area Behavior Centers for Disease Control and Prevention (U.S.)Clinical Communities Diffuse Diffusion Disclosure Discrimination Disinhibition Distress Epidemic Fostering Friends Fright Future Gays Goals Grant Guidelines HIV HIV Infections HIV Seropositivity Incidence Individual Information Dissemination Intervention Interview Judgment Label Latino Mediating Medical Minority Nature Participant Perception Population Prejudice Prevalence Prevention Prevention strategy Provider Reporting Research Resources Sexual Partners Source Stigmatization Surveys Tenofovir Time base disorder prevention emtricitabine experience follow-up high risk high risk population innovation men who have sex with men peer pre-exposure prophylaxis prevent prospective public health relevance response social social stigma therapy development truvada

项目摘要

DESCRIPTION (provided by applicant):Pre-Exposure Prophylaxis (PrEP) is a biomedical HIV prevention strategy with the potential to reduce the rate of new HIV infection among black and Latino men who have sex with men (BLMSM), two populations at the center of the U.S. HIV/AIDS epidemic. However, the social stigma currently associated with the use of PrEP (i.e. PrEP stigma) may negatively influence PrEP disclosure, diffusion, adherence and retention among BLMSM who adopt PrEP. The controversy and contention surrounding the implementation of PrEP in the gay community has led to the stigmatization of PrEP and those who use it. PrEP users may experience PrEP stigma in the form of negative perceptions (e.g., being judged, being unfairly treated), stigmatizing attributions (e.g., promiscuous, sexually irresponsible, mistakenly identified as HIV-positive), and stigmatizing practices (e.g., rejection, prejudice, discrimination) from friends, sex partners, providers and others. The goals of this study are to explore the nature and extent of PrEP stigma among BLMSM who have adopted PrEP and to assess its influence on PrEP disclosure, adherence and retention, and the diffusion of PrEP information to other potential BLMSM PrEP consumers. The specific aims of this study are: 1) to examine how BLMSM PrEP adopters experience PrEP stigma (e.g., anticipated, internalized, enacted); 2) to assess the extent and context of PrEP disclosure and dissemination of PrEP information by BLMSM PrEP users to other potential BLMSM PrEP consumers; and 3) to examine the influence of PrEP stigma, over time, on adherence and retention to PrEP among BLMSM PrEP adopters. To achieve these aims, this qualitative study will involve conducing in- depth interviews with 50 black (N = 25) and Latino (N = 25) MSM PrEP adopters and 20 black (N = 10) and Latino (N = 10) MSM non-PrEP adopters. BLMSM PrEP adopters will complete both a baseline and a 6-month follow-up interview. Follow-up interviews will assess changes in PrEP retention, adherence, disclosure and dissemination. Interviews with BLMSM non-PrEP adopters will elicit information about anticipated PrEP stigma and how this may have influenced decisions to seek or not seek PrEP. Interviews will also be conducted with 20 medical providers to assess their perceptions of PrEP and PrEP stigma and concerns about the implementation of PrEP. The findings from this study will inform the development of intervention activities that seek to prevent or mitigate the negative social experiences associated with PrEP adoption and to optimize diffusion and retention to PrEP among minority MSM.

描述（由适用提供）：暴露前预防（PREP）是一种生物医学的艾滋病毒预防策略，有可能降低与男性发生性关系的黑人和拉丁裔男性之间的新艾滋病毒感染率（BLMSM），这是美国艾滋病毒/艾滋病/艾滋病中心的两个人群。但是，目前与使用PREP（即准备污名）相关的社会污名可能会对采用PREP的BLMMSM中的PrEP披露，扩散，依从性和保留产生负面影响。围绕同性恋社区实施PREP的争议和争论导致了Prep的污名和使用它的人的污名化。准备用户可能会以负面看法的形式（例如，受到审判，受到不公平治疗）的形式，污名化属性（例如，滥交，性不负责任，错误地被识别为HIV阳性）和污名化的做法（例如，抑制，拒绝，拒绝，拒绝，录音，偏见，歧视）来自朋友，性伴侣，提供者和其他人。这项研究的目标是探索采用PREP并评估其对准备披露，依从性和保留的影响的BLMSM中的准备污名的性质和程度，以及将PREP信息扩散到其他潜在的BLMSM Prep消费者中。这项研究的具体目的是：1）检查BLMSM准备者如何经历准备污名（例如，预期，内部化，颁布）； 2）评估BLMSM PREP用户对其他潜在的BLMSM PREP消费者对PREP披露和传播PREP信息的范围和背景； 3）检查准备污名的影响，随着时间的流逝，对BLMMSM PREP采用者的依从性和保留率。为了实现这些目标，这项定性研究将涉及对50个黑色（n = 25）和拉丁裔（n = 25）MSM Prep采用者以及20个黑色（n = 10）和拉丁裔（n = 10）MSM非PREP采用者进行深度访谈。 BLMSM PREP的采用者将完成基线和6个月的后续采访。后续访谈将评估保留，依从性，披露和传播的变化。对BLMSM非PREP采用者的访谈将获取有关预期的预期污名的信息，以及这可能如何影响寻求或不寻求准备的决策。还将与20个医疗提供者进行访谈，以评估他们对准备和准备污名的看法，并担心实施PREP。这项研究的发现将为寻求干预活动的发展提供信息为了防止或减轻与采用预备有关的负面社会经历，并优化少数MSM的扩散和保留。