Medical Retina Fellowship

医学视网膜奖学金

• 批准号: 9556041
• 负责人: Catherine Cukras
• 金额: $ 16.8万
• 依托单位: NATIONAL EYE INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9556041
• 关键词: Age related macular degeneration; Alzheimer' s Disease; Angiography; Avastin; Blood; Clinical; Clinical Trials; Collaborations; DNA; Diabetic Retinopathy; Disease; Epidemiology; Evaluation; Eye diseases; Faculty; Fellowship; Follow-Up Studies; Fundus; Genetic study; HIV; Indocyanine Green; Lucentis; Medical; National Institute of Neurological Disorders and Stroke; Nerve Degeneration; Participant; Patients; Protocols documentation; Retina; Retinal; Retinal Diseases; Serous; Speed; Training; Translational Research; Treatment Protocols; age related; bevacizumab; biobank; clinical application; clinical material; clinically relevant; diabetic; epidemiology study; inhibitor/antagonist; macular edema; phase 1 study; screening

A number of medical retinal protocols have been conducted at the NEI clinical center. Many are phase 1 studies while others are studies in the screening and evaluation and treatment protocol. These provide patients for screening for trials and epidemiologic studies conducted by the Division of Epidemiology and Clinical Applications. These include the followup of Age-Related Eye Disease Study (AREDS2) and AREDS2 follow-up, lucentis or avastin (anti-VEGF therapy) for treatment of diabetic macular edema, while lucentis for a study of high speed indocyanine green angiography for age-related macular degeneration, treatment with microglial inhibitors for diabetic retinopathy and retinovascular occlusions, treatments for central serous retinopathy, and genetic studies of age-related macular degeneration. We have also had a biobank protocol where we would collect DNA and blood for a number of retinovascular diseases. We are also beginning a collaboration with the NINDS on evaluating the fundus of patients with Alzheimer's disease and with NINDS on HIV ocular findings in those with HIV associated neurodegeneration.

在NEI临床中心已经进行了许多医疗视网膜方案。 许多是第一阶段研究，而其他研究是筛查，评估和治疗方案的研究。 这些为患者提供了通过流行病学和临床应用划分进行的试验和流行病学研究的筛查。 其中包括与年龄相关的眼病研究（AREDS2）和AREDS2随访，卢森蒂斯（Lucentis）或阿avastin（抗VEGF治疗），用于治疗糖尿病黄斑水肿，而卢森蒂斯（Lucentis浆液性视网膜病和与年龄相关的黄斑变性的遗传研究。 我们还制定了生物库方案，我们将收集多种视网膜疾病的DNA和血液。 我们还开始与Ninds进行合作，以评估阿尔茨海默氏病患者的眼底，以及与HIV相关神经变性人群中的HIV眼癌发现的Ninds。