Planning for a National Non-Communicable Disease Center of Research Excellence

规划国家非传染性疾病卓越研究中心

• 批准号: 9337384
• 负责人: Dirk P Dittmer
• 金额: $ 25.18万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9337384
• 关键词: Achievement; Address; Africa South of the Sahara; Area; Attention; Basic Science; Biometry; California; Cardiovascular Diseases; Centers of Research Excellence; Clinic; Clinical; Clinical Trials Cooperative Group; Collaborations; Communicable Diseases; Communities; Comprehensive Cancer Center; Consensus; Core Facility; Country; Development; Educational process of instructing; Ensure; Environment; Faculty; Funding; Goals; Government; Grant; HIV; Health; Health Policy; Hospitals; Human Resources; Hygiene; Income; Information Systems; Injury; Institution; International; Investments; Kenya; Laboratories; Leadership; Letters; London; Los Angeles; Malawi; Malignant Neoplasms; Measurable; Measures; Medicine; Modeling; Movement; Needs Assessment; North Carolina; Operative Surgical Procedures; Outcome; Output; Ownership; Pathology; Patients; Pediatric Hospitals; Politics; Principal Investigator; Procedures; Public Health; Publications; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Research Support; Resources; Schools; South Africa; Teaching Hospitals; Training; Training Programs; Translating; Trauma; Tropical Medicine; Trust; United States National Institutes of Health; Universities; Zambia; anticancer research; base; burden of illness; clinical investigation; cohesion; college; low and middle-income countries; programs; research facility; response; success; ward

Project Summary Abstract This application is in response to RFA-CA15-007. It comprises a two-year planning period to develop a Malawi Center of Research Excellence for non-communicable diseases (NCDs), focused on cancer, injury, and cardiovascular disease (CVD). These three areas of concentration are of major public health importance with immense unmet need. They have been prioritized by our partner institutions in this application: the Malawi College of Medicine (COM) and Ministry of Health (MOH). Following the intent of the RFA the University of North Carolina (UNC) will serve as the high-income country partner institution for the application, based on its decades-long program in Malawi, long history of collaboration with COM and MOH, and deep involvement in cancer research activities specifically within Malawi. The planning grant will seek to engage US and International partners with significant NCD programs in Malawi, such as UCLA and Baylor College of Medicine, and others. This is a multiple principal investigators application with highly complementary expertise: Satish Gopal (UNC/COM; cancer; clinical investigation); Nyengo Mkandawire (COM; injury; clinical investigation); Mwapatsa Mipando (COM; cardiovascular disease; basic science); Dirk Dittmer (UNC; cancer; basic science). In addition, senior investigators and leadership from government and other supported research programs will participate as key personnel and consultants during the planning period, which leverages an impressive pool of faculty within and outside Malawi. The planning is to develop a center will include administrative, developmental, clinical, laboratory, biostatistics, and implementation cores and which may serve as a resource for the region, e.g. in pathology and surgery training. Partners will be invited during the planning period to contribute to a national plan for each of these, based on existing resources and activities across institutions, as well as new resources and activities that are collectively prioritized. Sustainability of the proposed center and its impact will be ensured by strong ownership from collaborating Malawian partners, including support by the highest levels of COM and MOH. We seek to establish active linkages of collaborating partners within Malawi to international institutions and research networks outside Malawi will allow the center to leverage these external relationships to achieve regional importance in sub-Saharan Africa. Finally, by catalyzing a broad national movement to address a rapidly growing NCD burden, the center will deliver measurable benefits to the people of Malawi.

项目摘要摘要 此应用程序响应RFA-CA15-007。它包括一个为期两年的计划期，以开发马拉维 非传染性疾病研究中心（NCD），专注于癌症，伤害和 心血管疾病（CVD）。这三个集中的领域具有重要的公共卫生重要性 巨大的未满足需求。我们的合作机构在此申请中优先考虑他们：马拉维 医学院（COM）和卫生部（MOH）。遵循RFA的意图 北卡罗来纳州（UNC）将根据其申请的高收入国家合作伙伴机构 马拉维数十年的计划，与COM和MOH合作的悠久历史以及深入参与 癌症研究活动专门在马拉维内部。计划赠款将寻求吸引我们，并 国际合作伙伴在马拉维拥有重要的NCD计划，例如加州大学洛杉矶分校和贝勒医学院， 还有其他。这是具有高度互补专业知识的多个主要研究人员的应用：Satish Gopal（UNC/COM；癌症；临床研究）； Nyengo Mkandawire（COM；伤害；临床调查）； mwapatsa mipando（COM；心血管疾病；基础科学）； Dirk Dittmer（UNC；癌症；基础科学）。 此外，政府和其他支持的研究计划的高级调查员和领导 在计划期间以关键人员和顾问的身份参与，这利用了令人印象深刻的池 马拉维内外的教师。计划是开发一个中心将包括行政管理 发展，临床，实验室，生物统计学和实施核心，可以作为资源 对于该地区，例如病理和手术训练。计划期间将邀请合作伙伴 基于机构的现有资源和活动，为每个国家的国家计划做出贡献 以及共同优先级的新资源和活动。拟议中心的可持续性和 合作马拉维伙伴的强大所有权将确保其影响 COM和MOH的最高水平。我们试图建立马拉维中合作伙伴的积极联系 到马拉维以外的国际机构和研究网络将允许该中心利用这些 外部关系以在撒哈拉以南非洲实现区域重要性。最后，通过催化宽阔的 国家运动以应对迅速增长的NCD负担，该中心将为 马拉维人。