Research and Capacity Building in Antimicrobial Resistance in West Africa

西非抗菌素耐药性研究和能力建设

• 批准号: 10685898
• 负责人: Eric Sampane-Donkor
• 金额: $ 24.72万
• 依托单位: UNIVERSITY OF GHANA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-15 至 2027-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10685898
• 关键词: Academic Training; Achievement; Acute; Address; Affect; Africa; Africa South of the Sahara; African; Age; Antimicrobial Resistance; Area; Bioinformatics; Career Choice; Clinical Microbiology; Country; Detection; Drug resistance; Ensure; Funding Agency; Genomics; Goals; Health; Human; Infection; Institution; International; Knowledge; Personal Satisfaction; Policies; Population Genetics; Positioning Attribute; Prevention; Research; Research Project Grants; Scientist; Sustainable Development; Training; Training Programs; Trust; United States National Institutes of Health; World Health Organization; disorder control; skills; Academic Training; Achievement; Acute; Address; Affect; Africa; Africa South of the Sahara; African; Age; Antimicrobial Resistance; Area; Bioinformatics; Career Choice; Clinical Microbiology; Country; Detection; Drug resistance; Ensure; Funding Agency; Genomics; Goals; Health; Human; Infection; Institution; International; Knowledge; Personal Satisfaction; Policies; Population Genetics; Positioning Attribute; Prevention; Research; Research Project Grants; Scientist; Sustainable Development; Training; Training Programs; Trust; United States National Institutes of Health; World Health Organization; disorder control; skills

ABSTRACT Antimicrobial resistance (AMR) is considered by the World Health Organization as one of the greatest global threats to human health in recent times and limits achievement of several of the Sustainable Development goals, in particular SDG3 (Ensure healthy lives and promote well-being for all at all ages). Although the burden of AMR disproportionately affects western sub-Saharan Africa, research capacity in the sub-region is very low and not well positioned to tackle the current demands of the problem. There is an acute shortage of professionals in West Africa in crucial areas that are essential to impact research, policy and disease control. There is a dearth of expertise for an array of crucial specialization relevant to AMR such as genomics, bioinformatics and population genetics compared to other African regions. These research capacity deficiencies could be addressed by focusing on long-term institutional training of junior scientists locally. However, currently, there are hardly any academic training programs in West Africa countries that focus on AMR. The objective of the proposed training programme is to increase research into the detection, prevention and treatment of drug-resistant infections in West Africa, expand knowledge and skills in clinical microbiology, and help junior scientists find a viable career path in AMR research. The long-term goal is to establish a core of West African scientists who advance the understanding and management of AMR and to support them to be competitive in obtaining research grants from international funding agencies such as the National Institutes of Health, USA and The Wellcome Trust, UK.

抽象的 世界卫生组织认为抗菌抗性（AMR）是 最近，全球对人类健康的最大威胁，并限制了几个 可持续发展目标，尤其是SDG3（确保健康的生活并促进福祉 对于所有年龄段）。尽管AMR的负担不成比例地影响西部撒哈拉以南 非洲，次区域的研究能力非常低，并且对应对当前 对问题的需求。西非的专业人士严重短缺关键 影响研究，政策和疾病控制至关重要的领域。缺乏 与AMR有关的一系列关键专业的专业知识，例如基因组学，生物信息学 与其他非洲地区相比，人口遗传学。这些研究能力缺陷 可以通过重点关注当地初级科学家的长期机构培训来解决。 但是，目前，西非国家几乎没有任何学术培训计划 专注于AMR。拟议培训计划的目的是增加对 西非的检测，预防和治疗耐药性感染，扩大知识 和临床微生物学的技能，并帮助初级科学家在AMR中找到可行的职业道路 研究。长期目标是建立西非科学家的核心 了解和管理AMR，并支持他们获得竞争力 来自美国国立卫生研究院等国际资助机构的研究赠款 和惠康信托基金会，英国。