Multiplexing biomarker analyzer

多重生物标志物分析仪

• 批准号: 9075947
• 负责人: ERICA A. GOLEMIS
• 金额: $ 7.59万
• 依托单位: RESEARCH INST OF FOX CHASE CAN CTR
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-01 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9075947
• 关键词: Biological Assay; Biological Markers; Data Quality; Detection; Disease model; Funding; Goals; Individual; Laboratories; Nucleic Acids; Output; Patients; Proteins; Request for Applications; Research Personnel; Sampling; Serum; Systems Analysis; Technology; Time; Tissues; United States National Institutes of Health; base; cost; cost effectiveness; high throughput screening; instrument; interest; miniaturize

 DESCRIPTION (provided by applicant): This application requests support for the purchase of a Luminex 100/200, a system that analyzes experimental samples (lysates, serum, tissues) for over 900 individual analytes utilizing a bead-based detection technology. The Luminex 100/200 instrument allows investigators to multiplex and miniaturize assays of either protein or nucleic acid biomarkers increasing data quality, throughput and cost effectiveness. The opportunity to centralize these studies and provide state-of-the-art high-throughput assays of a variety of analytes will minimize cost and time, while maximizing output. The specific projects of the 9 NIH funded laboratories detailed within this application vary widely in their scientific interests, however they share the common goal of pursuing translational endpoints within the context of patient samples or laboratory models of disease.

 描述（由应用程序提供）：此应用程序请求购买Luminex 100/200的支持，该系统分析了使用基于珠子的检测技术的900多个单独的分析物，该系统分析了实验样本（裂解物，血清，组织）。 Luminex 100/200仪器允许研究人员多重地并将蛋白质或核酸生物标志物的测定法提高数据质量，吞吐量和成本效益。将这些研究集中并提供对各种分析物的最先进的高通量评估的机会将最小化成本和时间，同时最大程度地提高产出。在本应用程序中详细介绍的9个NIH资助的实验室的特定项目因其科学利益而差异很大，但是它们共享了在患者样本或疾病实验室模型的背景下追求转化终点的共同目标。