2017 Microbial Population Biology Gordon Research Conference & Gordon Research Seminar

2017微生物种群生物学戈登研究会议

• 批准号: 9395217
• 负责人: Eva M. Top
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9395217
• 关键词: Address; Affect; Antibiotic Resistance; Basic Science; Biodiversity; Communicable Diseases; Country; Data; Development; Discipline; Disease; Ecology; Emerging Communicable Diseases; Evolution; Female; Genetic Epistasis; Genetic Variation; Genome; Geography; Global Warming; Goals; Health; Human; Immune Evasion; Industry; International; Lead; Life; Maintenance; Mentors; Methods; Microbe; Modernization; Natural Resources; North America; Participant; Planet Earth; Population; Population Biology; Postdoctoral Fellow; Race; Research; Research Personnel; Science; Scientist; Structure; Technology; Testing; Virulence; Woman; Work; arm; career; career networking; frontier; genome sequencing; graduate student; improved; insight; life history; meetings; microbial; microorganism interaction; new technology; novel; pathogen; professor; symposium; theories; whole genome; young woman

Project Summary/Abstract The richness of diversity found in our microbial world influences both human health and disease. The latter is evident from immune evasion and the evolution and spread of antibiotic resistance among pathogens, which threatens our ability to effectively treat infectious diseases. Since 1985 the Microbial Population Biology Gordon Research Conference (GRC) has been the premier international meeting on the evolution and ecology of microbial populations. Its long-term objective since 1985 is to improve our understanding of the evolutionary forces that lead to the emergence and maintenance of genetic diversity within and between microbial species. It typically attracts an outstanding and diverse group of scientists who work at the forefront of their discipline. In addition an accompanying Gordon Research Seminar (GRS) for graduate students and postdoctoral fellows precedes the conference since 2013. The specific goal of the 2017 GRC & GRS is to bring together thought leaders from a spectrum of disciplines to present and discuss empirical data and theoretical concepts pertinent to the adaptive evolution of not only microbes, but all other forms of life. The conference and seminar have the following specific aims. Specific Aim 1: Interweave the findings of basic research done to develop and test evolutionary theory with studies done to meet the modern day challenges of emerging infectious diseases, the arms race of antibiotic resistance, sustainable use of natural resources, and global warming. This will be done in nine non-overlapping sessions with the following topics: (i) Evolution and emergence of infectious diseases, (ii) host-microbe coevolution, (iii) evolutionary consequences of epistasis, (iv) the evolution and spread of antibiotic resistance, (v) antibiotic resistance in the field, (vi) genome evolution, (vii) new technologies lead to new opportunities, (viii) ecological interactions of microbial populations, and (ix) the effect of spatial structure on biodiversity. Specific Aim 2: Emphasize novel methods that are needed to better understand the evolution of microbial pathogens and the interactions with each other and their host. Significant advances in technology such as whole genome sequencing have accelerated and deepened our ability to explore the mechanisms of microbial evolution and understand the diversity within microbial populations. One session in particular will focus entirely on novel methods. Specific Aim 3: Highlight the work of younger scientists and enhance the diversity of conference participants. Among the 33 speakers and discussion leaders confirmed so far, 15 are female, 15 are still at the assistant professor level or equivalent, and 20 are from 12 countries other than the US. It is expected that this great diversity in speakers will attract a greater ethnic and geographic diversity among the participants than is typical for this GRC. Moreover, the high representation of young especially female speakers will encourage young woman scientists to continue careers in science. Specific Aim 4: Through a weekend-long GRS for graduate students and postdoctoral fellows, promote scientific interactions among young researchers and offer mentoring and career advice.

项目摘要/摘要 在我们的微生物世界中发现的多样性都会影响人类健康和疾病。后者是 从免疫逃避以及抗生素耐药性在病原体中的进化和传播中可以明显看出。 威胁我们有效治疗传染病的能力。自1985年以来，微生物种群生物学 戈登研究会议（GRC）一直是有关进化与生态的首要国际会议 微生物种群。自1985年以来的长期目标是提高我们对进化的理解 导致微生物物种内部和微生物之间遗传多样性的出现和维持的力。 它通常会吸引在学科最前沿工作的一群杰出而多样的科学家。在 为研究生和博士后研究员提供了陪同的戈登研究研讨会（GRS） 自2013年以来的会议之前。2017年GRC＆GRS的具体目标是将思想汇集在一起 来自一系列学科的领导者，介绍和讨论经验数据和理论概念相关的理论概念 不仅是微生物，而且所有其他形式的生活形式的适应性演变。会议和研讨会有 遵循特定目标。特定目的1：交织以开发和测试的基础研究结果 进化论的研究是为了应对现代传染病的现代挑战， 抗生素抵抗，自然资源的可持续使用和全球变暖的军备竞赛。这将完成 在九个不重叠的会议中，有以下主题：（i）传染病的进化和出现， （ii）宿主 - 微生物共同进化，（iii）上位症的进化后果，（iv） 抗生素耐药性，（v）田间抗生素抗性，（vi）基因组进化，（vii）新技术导致 新机会，（viii）微生物种群的生态相互作用，以及（ix）空间结构的影响 关于生物多样性。特定目的2：强调需要更好地理解进化所需的新颖方法 微生物病原体以及彼此及其宿主的相互作用。技术的重大进展 例如整个基因组测序加速并加深了我们探索机制的能力 微生物进化并了解微生物种群中的多样性。特别是一个会话 完全专注于新方法。特定目的3：突出年轻科学家的工作，并增强 会议参与者的多样性。在到目前为止确认的33位发言人和讨论领袖中，有15位是 女性，15岁仍在助理教授级别或同等学历，有20个来自其他12个国家 /地区。 我们。预计演讲者的这种巨大多样性将吸引更大的种族和地理多样性 在参与者中，该GRC的典型是典型的。而且，尤其是年轻人的高度代表 女演讲者将鼓励年轻女科学家继续从事科学职业。具体目标4： 通过为研究生和博士后研究员提供一个周末的GRS，促进科学互动 在年轻的研究人员中，并提供指导和职业建议。