2017 Microbial Population Biology Gordon Research Conference & Gordon Research Seminar

2017微生物种群生物学戈登研究会议

• 批准号: 9395217
• 负责人: Eva M. Top
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9395217
• 关键词: Address; Affect; Antibiotic Resistance; Basic Science; Biodiversity; Communicable Diseases; Country; Data; Development; Discipline; Disease; Ecology; Emerging Communicable Diseases; Evolution; Female; Genetic Epistasis; Genetic Variation; Genome; Geography; Global Warming; Goals; Health; Human; Immune Evasion; Industry; International; Lead; Life; Maintenance; Mentors; Methods; Microbe; Modernization; Natural Resources; North America; Participant; Planet Earth; Population; Population Biology; Postdoctoral Fellow; Race; Research; Research Personnel; Science; Scientist; Structure; Technology; Testing; Virulence; Woman; Work; arm; career; career networking; frontier; genome sequencing; graduate student; improved; insight; life history; meetings; microbial; microorganism interaction; new technology; novel; pathogen; professor; symposium; theories; whole genome; young woman

Project Summary/Abstract The richness of diversity found in our microbial world influences both human health and disease. The latter is evident from immune evasion and the evolution and spread of antibiotic resistance among pathogens, which threatens our ability to effectively treat infectious diseases. Since 1985 the Microbial Population Biology Gordon Research Conference (GRC) has been the premier international meeting on the evolution and ecology of microbial populations. Its long-term objective since 1985 is to improve our understanding of the evolutionary forces that lead to the emergence and maintenance of genetic diversity within and between microbial species. It typically attracts an outstanding and diverse group of scientists who work at the forefront of their discipline. In addition an accompanying Gordon Research Seminar (GRS) for graduate students and postdoctoral fellows precedes the conference since 2013. The specific goal of the 2017 GRC & GRS is to bring together thought leaders from a spectrum of disciplines to present and discuss empirical data and theoretical concepts pertinent to the adaptive evolution of not only microbes, but all other forms of life. The conference and seminar have the following specific aims. Specific Aim 1: Interweave the findings of basic research done to develop and test evolutionary theory with studies done to meet the modern day challenges of emerging infectious diseases, the arms race of antibiotic resistance, sustainable use of natural resources, and global warming. This will be done in nine non-overlapping sessions with the following topics: (i) Evolution and emergence of infectious diseases, (ii) host-microbe coevolution, (iii) evolutionary consequences of epistasis, (iv) the evolution and spread of antibiotic resistance, (v) antibiotic resistance in the field, (vi) genome evolution, (vii) new technologies lead to new opportunities, (viii) ecological interactions of microbial populations, and (ix) the effect of spatial structure on biodiversity. Specific Aim 2: Emphasize novel methods that are needed to better understand the evolution of microbial pathogens and the interactions with each other and their host. Significant advances in technology such as whole genome sequencing have accelerated and deepened our ability to explore the mechanisms of microbial evolution and understand the diversity within microbial populations. One session in particular will focus entirely on novel methods. Specific Aim 3: Highlight the work of younger scientists and enhance the diversity of conference participants. Among the 33 speakers and discussion leaders confirmed so far, 15 are female, 15 are still at the assistant professor level or equivalent, and 20 are from 12 countries other than the US. It is expected that this great diversity in speakers will attract a greater ethnic and geographic diversity among the participants than is typical for this GRC. Moreover, the high representation of young especially female speakers will encourage young woman scientists to continue careers in science. Specific Aim 4: Through a weekend-long GRS for graduate students and postdoctoral fellows, promote scientific interactions among young researchers and offer mentoring and career advice.

项目概要/摘要 微生物世界中丰富的多样性影响着人类的健康和疾病。后者是 从免疫逃避以及病原体中抗生素耐药性的进化和传播可以明显看出， 威胁我们有效治疗传染病的能力。自 1985 年以来微生物种群生物学 戈登研究会议（GRC）是关于进化和生态学的首要国际会议 微生物种群。自 1985 年以来，其长期目标是提高我们对进化论的理解 导致微生物物种内部和之间遗传多样性的出现和维持的力量。 它通常吸引一群杰出且多元化的科学家，他们在各自学科的最前沿工作。在 另外还为研究生和博士后研究员举办了戈登研究研讨会 (GRS) 自 2013 年开始召开会议。2017 年 GRC 和 GRS 的具体目标是汇集思想 来自各个学科的领导者展示和讨论相关的经验数据和理论概念 不仅是微生物的适应性进化，而且是所有其他生命形式的适应性进化。会议和研讨会有 遵循特定目标。具体目标 1：将基础研究成果交织在一起进行开发和测试 进化论以及为应对新出现的传染病的现代挑战而进行的研究， 抗生素耐药性的军备竞赛、自然资源的可持续利用和全球变暖。这将完成 分九场互不重叠的会议进行，主题如下： (i) 传染病的演变和出现， (ii) 宿主-微生物共同进化，(iii) 上位性的进化后果，(iv) 进化和传播 抗生素耐药性，(v) 现场抗生素耐药性，(vi) 基因组进化，(vii) 新技术导致 新机遇，(viii) 微生物种群的生态相互作用，以及 (ix) 空间结构的影响 关于生物多样性。具体目标 2：强调更好地理解进化所需的新方法 微生物病原体及其彼此及其宿主之间的相互作用。技术的重大进步 全基因组测序等加速并加深了我们探索机制的能力 微生物进化并了解微生物种群内的多样性。特别是一场会议将 完全专注于新颖的方法。具体目标 3：突出年轻科学家的工作并增强 会议参与者的多样性。目前已确认的 33 名演讲者和讨论负责人中，有 15 人是 女性，15人仍为助理教授或同等级别，20人来自除美国之外的12个国家 我们。预计说话者的这种巨大多样性将吸引更大的种族和地理多样性 参与者之间的差异比本次 GRC 的典型情况要多。此外，年轻人尤其是年轻人的比例很高 女性演讲者将鼓励年轻女科学家继续从事科学事业。具体目标 4： 通过为研究生和博士后研究员提供为期周末的 GRS，促进科学互动 年轻研究人员中，并提供指导和职业建议。