Educating Physician-Neuroscientists: The R25 at UCSF

教育医师神经科学家：UCSF 的 R25

• 批准号: 9308006
• 负责人: STEPHEN L HAUSER
• 金额: $ 94.38万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9308006
• 关键词: Adult; Alzheimer' s Disease; Brain; Cancer Education Grant Program; Clinical; Clinical Sciences; Collaborations; Communities; Drug Industry; Education Projects; Ensure; Environment; Evolution; Faculty; Fellowship; Fostering; Foundations; Funding; Funding Agency; Future; Goals; Grant; Heart; Home environment; Institutes; K-Series Research Career Programs; Laboratories; Laboratory Research; Life Expectancy; Manuscripts; Medical; Medical Students; Mission; Neurology; Neurosciences; Paper; Participant; Patients; Peer Review; Physicians; Positioning Attribute; Prevention; Prevention strategy; Research; Research Personnel; Research Support; Research Training; Residencies; Resources; Scientist; Talents; Time; Training; Translational Research; United States; United States National Institutes of Health; Universities; base; career; career development; education research; experience; improved; interest; multidisciplinary; nervous system disorder; neuropathology; neurosurgery; next generation; programs; public health relevance; research and development; skill acquisition; success; symposium; teacher; translational neuroscience; treatment strategy

 DESCRIPTION (provided by applicant): Educating Physician-Neuroscientists: The Department of Neurology at UCSF has been the institutional sponsor for the R25 program at UCSF over the past 5 years and is the home department for this application renewal. Both neurology and neuropathology have supported outstanding research training candidates through this program. We are pleased that the Department of Neurosurgery has committed to becoming an active participant in the program and is well-represented in this renewal application. The Department of Neurology has an excellent record for attracting outstanding medical students destined for neurology. Out of 250 applications from US medical graduates for 10 adult neurology positions in 2014, we were fortunate to match all 10 positions to the top eleven applicants on our rank list. The department aspires to train the next generation of national neurology leaders and our neurology residency graduates transition in high numbers to long term academic careers as laboratory investigators, clinical science (patient- based) investigators, and university-based clinician teachers. The opening of the Neurology Research building at the Mission Bay campus (see facilities below) has resulted in greatly expanded opportunities for research trainees and collaboration between laboratory research programs in a common space and with nearby research programs (e.g.-Gladstone Institute). The intellectual environment is exciting for trainees. Monthly multidisciplinary conferences (e.g.-Brain Club) host speakers who discuss translational science issues that attract both clinicians and bench scientists. These conferences are followed by an opportunity to informally mix with colleagues who have diverse clinical and scientific interests. The R25 has been a crucial linchpin for the development of research skills by our talented young physician-scientists in neurology and neuropathology at UCSF. In the era of sequestration, which has challenged the stability of mid-career and senior neuroscientists, the R25 has become an even more important stable NIH program for ensuring that our most talented early career neuroscientists are well-supported. Our early track record among participants who have completed the program is encouraging. Of four trainees who have completed the program at UCSF, all continue to be engaged in laboratory research. One has received K-award funding, one has applied for K-award funding and received a very favorable score, and the other two plans to apply for K-award funding in the next year. Two have received funding from sources other than NIH (CIRM, Giannini Foundation, and Alzheimer's Disease Research Center Pilot Grant). One is an author on a peer-reviewed papers related to the R25 research program and another has a manuscript under review. Two trainees (one neuropathology and one neurology) had a change of heart and moved to careers in the pharmaceutical industry. While the program is still early in evolution, it is clear that UCS can provide the training time and research environment to foster early research career development for physician-scientists.

 描述（由申请提供）：教育医师 - 神秘主义者：UCSF神经病学系在过去5年中一直是UCSF R25计划的机构赞助商，并且是该申请续订的内政部。神经病学和神经病理学都通过该计划支持了杰出的研究培训候选者。我们很高兴神经病学系致力于成为该计划的积极参与者，并在此续签申请中得到了很好的代表。神经病学系在吸引注定神经病学的杰出医学生方面拥有出色的记录。在2014年美国医学毕业生的250个申请中，我们很幸运地将所有10个职位与我们的等级名单上的11个申请匹配。该部门渴望培训下一代国家神经病学领导者，而我们的神经病学居民毕业生则以实验室研究人员，临床科学（基于患者）研究人员和大学的临床教师的身份过渡到长期的学术职业。 Mission Bay校园的神经病学研究大楼的开业（请参见下面的设施）为研究受训者提供了很大的扩展机会，并在公共空间和近乎研究计划（例如 - 格拉德斯通研究所）中的实验室研究计划之间的合作机会扩大了。对于学员来说，智能环境令人兴奋。每月的多学科会议（例如 - 脑俱乐部）主持人演讲者，讨论引起临床医生和替补科学家的转化科学问题。这些会议之后，有机会与具有潜水员临床和科学利益的同事非正式地混合。 R25一直是UCSF神经病学和神经病理学的年轻身体科学家发展研究技能的关键关键。在挑战中期和高级神经科学家的稳定性的会议时代，R25已成为一个更重要的稳定NIH计划，以确保我们最有才华的早期职业神经科学家得到了很好的支持。我们在完成该计划的参与者中的早期记录令人鼓舞。在UCSF完成该计划的四名学员中，所有学员都继续从事实验室研究。一个人已经获得了K-award资金，一个申请了K-award资金并获得了非常有利的分数，而其他两个计划在明年申请K-award资金。两人还从NIH（Cirm，Giannini Foundation和Alzheimer's Diseary Research Center Pilot Grant）的其他来源获得了资金。一个是与R25研究计划有关的同行评审论文的作者，另一个是手稿正在审查中。两名受训者（一名神经病理学和一名神经病学）改变了心脏，并转向了制药行业的职业。尽管该计划仍在进化中，但很明显，UCS可以提供​​培训时间和研究环境，以促进物理科学家的早期研究职业发展。