Tagging of Histopathology Specimens with Light-Activated RFID p-Chips

使用光激活 RFID p 芯片标记组织病理学样本

基本信息

批准号：
8542871
负责人：
WLODEK MANDECKI
金额：
$ 59.25万
依托单位：
PHARMASEQ, INC.
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-02-01 至 2015-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8542871
关键词：
Adherence Adhesives Adoption Amplifiers Appearance Area Benchmarking Charge Chemicals Clinical Trials Communication Computer software Computers Contractor Custom Databases Diagnostic Docking Electronics Epoxy Compounds Evaluation Feedback Frequencies Glass Goals Hand Histopathology Hospitals Human Resources Hybrids Institution Label Laboratories Lasers Light Link Liquid substance Maintenance Manufacturer Name Mechanics Medical Medical Research Methods Molds Noise Optics Pathology Performance Play Polypropylenes Printing Process Protocols documentation Provider Readability Reader Reading Research Retrieval Robot Robotics Role Sampling Scanning Side Signal Transduction Silicon Slide Solutions Solvents Source Specimen System Systems Development Technology Temperature Testing Texas Tissue Sample Tissue Stains Tissues Update Validation Wireless Technology Work anticancer research base chemical stability cost design drug discovery improved instrument knowledge base lens programs prototype validation studies

项目摘要

DESCRIPTION (provided by applicant): The purpose of the present project is to develop and validate the use of ultra-small RFID chips to tag and track tissue cassettes and glass slides that are used in histopathology laboratories. The system is based on the PharmaSeq laser light-activated microtransponder, also known as "p-Chip". The chip's major advantages are its small size (500 ¿m x 500 ¿m x 100 ¿m), unitary design, inertness, ease of use and very low cost. The system consists of the p-Chip-tagged glass slides and tissue cassettes, a stationary reader, a portable reader for trays with slides, and associated software that allows integration with common database software. The main goals of the project are to: 1) develop semi-automated methods of attaching p-Chips to slides and cassettes, 2) build advanced prototypes of the ID reader (wand) and improve key features, such as the form factors for reading each type of container, 3) improve the design of the p-Chip to increase the read range and refine methods of their post-fabrication processing, and 4) conduct extensive pilot test studies with outside collaborators to validate the system. The ID readers will have a modified optical system and will feature wireless communication between the reader and a workstation or central computer. The adoption of the system will improve reliability for tagging and tracking tissue samples.

描述（由申请人提供）：本项目的目的是开发和验证超小型 RFID 芯片的使用，以标记和跟踪组织病理学实验室中使用的组织盒和载玻片。该系统基于 PharmaSeq 激光器。光激活微应答器，也称为“p-Chip” 该芯片的主要优点是尺寸小（500 m x 500 m x）。 100 µm），单一设计、惰性、易于使用且成本极低。该系统由带有 p-Chip 标签的载玻片和组织盒、固定式读取器、用于载玻片托盘的便携式读取器以及相关软件组成。允许与通用数据库软件集成，该项目的主要目标是：1）开发将 p-Chips 连接到载玻片和盒的半自动化方法，2）构建先进的原型。 ID 读取器（棒）并改进关键功能，例如读取每种类型容器的外形尺寸，3) 改进 p 芯片的设计，以增加读取范围和制造后处理的细化方法，以及 4 ）与外部合作者进行广泛的试点测试研究，以验证该系统，ID读取器将具有改进的光学系统，并将在读取器和工作站或中央计算机之间进行无线通信。该系统的采用将提高标签和跟踪的可靠性。组织样本。