Center for Neuroplasticity at the University of Puerto Rico

波多黎各大学神经可塑性中心

• 批准号: 8687677
• 负责人: JOSHUA J.C. ROSENTHAL
• 金额: $ 213.59万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8687677
• 关键词: Address; Administrator; Advisory Committees; Atomic Force Microscopy; Basic Science; Behavior Disorders; Benchmarking; Biomedical Research; Centers of Research Excellence; Collaborations; Commit; Communities; Complement; Development; Electrophysiology (science); Ensure; Environment; Faculty; Familiarity; Flow Cytometry; Fostering; Functional disorder; Funding; Future; Genetic; Goals; Grant; Homeostasis; Image; Individual; Institutes; Institution; Investigation; Island; Laboratories; Leadership; Manuscripts; Medical; Mentors; Mentorship; Microscope; Modeling; Nanotechnology; Neurobiology; Neuronal Plasticity; Neurons; Neurosciences; Pathway interactions; Piedra; Preparation; Property; Proteomics; Puerto Rico; Recording of previous events; Records; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Science; Scientific Advances and Accomplishments; Scientist; Series; Sleep; Spinal cord injury; Staging; Stress; System; Technology; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Work; Writing; base; biomedical resource; career; career development; design; experience; improved; innovation; instrument; instrumentation; interdisciplinary collaboration; interest; member; multidisciplinary; nervous system disorder; neuroadaptation; neuroimaging; operation; programs; public health relevance; residence; symposium; two-photon

DESCRIPTION (provided by applicant): The University of Puerto Rico (UPR) Medical Sciences Campus proposes to establish a COBRE Center that will significantly strengthen the research infrastructure of the institution and that will impact biomedical investigation throughout the island. The specific aims of this COBRE Center for Neuroplasticity at the University of Puerto Rico are to: 1) Foster development of junior investigators into competitive researchers working on projects with direct biomedical significance. An intensive mentoring program will be implemented with the goal of creating a "culture of research" comparable to that of major research-intensive universities. 2) Provide a Neuroimaging and Electrophysiology Facility (NIEF) that will offer state-of-the-art instrumentation, training, and expertise to the neuroscienc community of Puerto Rico. The NIEF will be located in the Institute of Neurobiology, but will incorporate ultra-high-end instrumentation in the new Biomolecular Sciences Building (BSB) after the COBRE has become well-established at the Institute; 3) Partner with IDeA Networks of Biomedical Research Excellence (INBRE) entities in Puerto Rico; 4) Support programmatic activities that increase interdisciplinary collaborations at the basic research level. The major strengths of the proposed COBRE include: 1) the PI, who is both an accomplished researcher with extensive funding and advisory activities within the NIH, and an experienced administrator with a history of successful initiation of research and training programs; 2) the team of young, aggressive and highly committed scientists; 3) enhanced mentorship possibilities provided by the current level of intellectual and scientific accomplishment present at the Institute of Neurobiology; 3) rational planning for the future by deployment of the new BSB as a centralized hub for integrated and collaborative research in the future of the COBRE Center for Neuroplasticity; 4) the full commitment of the UPR Administration toward assuring the stated goals of the project. This UPR COBRE Center should define pathways and benchmarks for basic and translational research across the UPR system for the next decades.

描述（由申请人提供）：波多黎各大学 (UPR) 医学科学校区提议建立一个 COBRE 中心，该中心将显着加强该机构的研究基础设施，并将影响全岛的生物医学研究。波多黎各大学 COBRE 神经可塑性中心的具体目标是： 1) 促进初级研究人员发展成为从事具有直接生物医学意义的项目的有竞争力的研究人员。将实施强化指导计划，目标是创造可与主要研究密集型大学相媲美的“研究文化”。 2) 提供神经影像和电生理学设施 (NIEF)，为波多黎各神经科学界提供最先进的仪器、培训和专业知识。 NIEF 将设在神经生物学研究所，但在 COBRE 在该研究所建立完善后，将在新的生物分子科学大楼 (BSB) 中纳入超高端仪器； 3) 与波多黎各 IDeA 生物医学卓越研究网络 (INBRE) 实体合作； 4) 支持加强基础研究层面跨学科合作的计划活动。拟议的 COBRE 的主要优势包括： 1) PI，他既是一位在 NIH 内拥有广泛资助和咨询活动的有成就的研究人员，也是一位经验丰富的管理人员，具有成功启动研究和培训项目的历史； 2）年轻、进取、高度敬业的科学家团队； 3）神经生物学研究所目前的智力和科学成就水平提供了增强的指导可能性； 3) 通过部署新的 BSB 作为 COBRE 神经可塑性中心未来综合和协作研究的集中枢纽，对未来进行合理规划； 4) 普遍定期审议主管部门对确保项目既定目标的充分承诺。 UPR COBRE 中心应该为未来几十年 UPR 系统的基础研究和转化研究确定路径和基准。