Measurement of nicotine dependence among adolescent & young adult cigarillo users

青少年尼古丁依赖的测量

• 批准号: 9330123
• 负责人: SUSAN A. FLOCKE
• 金额: $ 49.73万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9330123
• 关键词: Acer; Address; Adolescent; Adolescent Risk Behavior; Adolescent and Young Adult; Adult; Affect; Attention; Biological Markers; Breathing; Characteristics; Chemicals; Cigar; Cigarette; Cigarette Smoker; Clinical Treatment; Data; Dependence; Development; Disease; Enrollment; Evaluation; Exposure to; Family Smoking Prevention and Tobacco Control Act; Flavoring; Frequencies; Future; Gold; Individual; Interview; Label; Measurement; Measures; Methods; Modeling; Nicotine; Nicotine Dependence; Ohio; Oral Tobacco; Patient Self-Report; Pattern; Performance; Periodicity; Phase; Prevalence; Regulation; Reporting; Research; Sales; Sampling; Smoke; Smoker; Smoking; Smoking Behavior; Speed; Strawberries; Substance abuse problem; Surveys; Symptoms; Syndrome; Testing; Tobacco; Tobacco Use Cessation; Tobacco use; United States; Withdrawal Symptom; Work; Youth; addiction; contextual factors; design; instrument; phase 3 study; programs; public health relevance; school district; urban school; young adult

DESCRIPTION (provided by applicant): Between 2000 and 2012 cigar, cigarillo, and little cigar (CCLC) use has increased 124%. Adolescents and young adults are the most prevalent users. For some states and urban school districts, including Cleveland, Ohio, the use of CCLC among adolescents now exceeds the use of cigarettes. Despite the increase in CCLC use among youth, attention to potential nicotine dependence (ND) among users of these products has been largely ignored. Recent evidence shows that users of CCLC do inhale when smoking and that, when compared to cigarettes, CCLC products contain as much if not more of the highly addictive chemical nicotine. Therefore, assessing ND among CCLC users is an important step to inform the extent to which these products are causing harm among users and thus, should be subjected to the same regulations as cigarettes. Patterns of use and the speed and method with which nicotine is physically received differ by tobacco product; because of this Fagerstrom and colleagues suggest that product-specific measures are needed to more precisely assess the level of ND among users. To our knowledge no measure of ND has been adapted for CCLC users nor has there been a new measure created for this purpose. This represents a significant gap in research we aim to address by establishing a measure of ND symptoms that is relevant, valid and reliable for adolescents and young adult CCLC users. Using an array of rigorous methods including qualitative in-depth interviews, Rasch modeling for measure development, and survey and biomarker data, the proposed project will contribute to the reliable and valid measurement of ND among CCLC users. The final CCLC ND measure will be administered to large samples of adolescents using the Youth Risk Behavior Survey (YRBS) to assess the prevalence of ND symptoms among CCLC users. The findings from this study will guide decisions regarding the appropriate implementation and scope of CCLC product regulation that is parallel to cigarettes with regard to warning labels, harmful constituent reporting, and regulation of other aspects that have been shown to influence youth access to and consumption of tobacco projects including packaging and product placement for sale.

描述（由申请人提供）：在2000年至2012年雪茄，雪茄和小雪茄（CCLC）使用之间增加了124％。青少年和年轻人是最普遍的使用者。对于某些州和城市学区（包括俄亥俄州克利夫兰），在青少年中使用CCLC现在超过了香烟的使用。尽管CCLC在青年中使用增加了，但这些产品使用者对潜在的尼古丁依赖（ND）的关注在很大程度上被忽略了。最近的证据表明，CCLC的使用者在吸烟时会吸入吸气，并且与香烟相比，CCLC产品含有更多甚至更多的高度上瘾的化学尼古丁。因此，评估CCLC用户之间的ND是告知这些产品在多大程度上造成用户造成伤害的重要性的重要步骤，因此应遵守与香烟相同的法规。烟草产物的使用方式以及物理接收的尼古丁的速度和方法不同；由于这个fagerstrom及其同事表明，需要采取特定于产品的措施来更精确地评​​估用户之间的ND水平。据我们所知，没有针对CCLC用户的ND措施，也没有为此目的创建一种新的措施。这是我们旨在通过建立与青少年和年轻成人CCLC使用者相关，有效且可靠的ND症状来解决的研究差距的一个重大差距。使用一系列严格的方法，包括定性的深入访谈，用于测量开发的Rasch建模以及调查和生物标志物数据，拟议的项目将有助于CCLC用户对ND的可靠和有效测量。最终的CCLC措施将使用青少年风险行为调查（YRB）对大型青少年样本进行管理，以评估CCLC使用者中ND症状的患病率。这项研究的发现将指导有关CCLC产品调节的适当实施和范围的决策，这些决策与有关警告标签，有害成分报告以及对其他方面的调节，这些方案与香烟相似，这些方面已被证明会影响青年对烟草项目的访问和消费，包括包装和产品的销售。