1/2 The Alabama State University/UAB Comprehensive Cancer Center Partnership

1/2 阿拉巴马州立大学/UAB 综合癌症中心合作伙伴关系

基本信息

批准号：
9341909
负责人：
UPENDER MANNE
金额：
$ 19.18万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-09-23 至 2019-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9341909
关键词：
Address Advisory Committees African American Alabama Area Basic Cancer Research Basic Science Bioethics Bioinformatics Biometry Cancer Research Project Characteristics Collaborations Colorectal Cancer Communities Community Health Complex Comprehensive Cancer Center Consultations Continuity of Patient Care Core Facility Cultural Sensitivity Development Drops Education Educational Curriculum Environment Ethics Evaluation Faculty Funding Genetic Geography Goals Health Educators Health Professional Health Services Accessibility Healthcare Heart Historically Black Colleges and Universities Immune Incidence Institution Life Style Link Malignant Neoplasms Malignant neoplasm of prostate Mentors Mentorship Minority Minority-Serving Institution Morals Morbidity - disease rate Nature Organizational Change Outcome Patients Pilot Projects Population Research Research Ethics Research Infrastructure Research Personnel Research Project Grants Research Training Scientist Social Behavior Source Students System Talents Testing Training Training and Education Universities University of Alabama at Birmingham Cancer Center anticancer research base burden of illness cancer care cancer health disparity career career development caucasian American design ethnic minority population graduate student health disparity interest member minority communities minority investigator minority scientist molecular marker mortality multidisciplinary novel outreach programs public health relevance socioeconomics student training study population success tumor progression undergraduate education undergraduate student underserved minority

项目摘要

DESCRIPTION (provided by applicant): This application is to establish a Partnership between Alabama State University (ASU) and the UAB Comprehensive Cancer Center (UAB CCC). The Partnership, located in the heart of the Southeast, a region with a large, historically underserved African American population, has goals of attaining excellence in research focused on cancer health disparities. The two institutions possess unique strengths that supplement each other. At ASU, which is classified as a historically black college and university (HBCU), more than 90% of students and more than 60% of the faculty belong to an underserved minority community in which health disparities are a significant issue in various areas, including cancer. The UAB CCC, in contrast, has developed an extensive infrastructure and critical mass of scientists that are necessary for a sustained research program. Still, ASU has a cultural sensitivity and perspective that may be deficient in the UAB CCC. Thus, the partners will facilitate collaborations in cancer-related research, training (career development), and education to aid this underserved community. UAB CCC faculty/scientists will cooperate with faculty and students at ASU and thereby initiate cancer research programs, creating an conduit for ASU faculty and students to pursue cancer research programs. The proposed effort will engage underserved groups by providing advanced research in prostate and colorectal cancer (both of which are major cancer health disparities for African Americans), by providing training to students and faculty members and by introducing topics related to cancer health disparities into the undergraduate and graduate curriculum at ASU. The proposed Partnership has an Administrative Core, a Cancer Research Program with two functioning projects, and a Cancer Training and Education Program. Within the Administrative Core, there are Bioethics Support, Biostatistics/Bioinformatics Support, and Evaluation Support. The Partnership will be guided by an Internal Advisory Committee, which will consist of two distinguished scientists of each institution; an Executive Committee with members of both institutions; and, for each organization, a Partnership Institutional Committee. The Cancer Training and Education Program will reach talented students and faculty at ASU, linking them to established investigators and to the research infrastructure at the UAB CCC, and facilitate faculty, graduate, and undergraduate student and education in the area of cancer research in order to increase the number of minority investigators involved in cancer research. The goal of the Bioethics support will be to provide exceptional bioethics education, training, guidance, and consultation throughout the Partnership. The goal of the Biostatistics/Bioinformatics support will be to address the statistical/bioinformatics needs of the research projects sponsored by the Partnership. The specific aims for the Partnership are: (1) to enhance, by development of junior faculty members, the research and administrative infrastructure to conduct competitive basic and community-based cancer research at ASU; (2) to develop investigators committed to research in cancer disparities at both partnering institutions; and (3) to establish a pipeline of minority cancer disparity researchers and health professionals between ASU and UAB.

描述（由申请人提供）：本申请旨在建立阿拉巴马州立大学 (ASU) 和 UAB 综合癌症中心 (UAB CCC) 之间的合作伙伴关系。该合作伙伴关系位于东南部的中心地带，该地区拥有大型历史悠久的地区。服务不足的亚利桑那州立大学 (HBCU) 的 90% 以上都是非裔美国人，他们的目标是在癌症健康差异研究方面取得卓越成就。学生和超过 60% 的教职人员属于服务不足的少数族裔社区，其中健康差异是包括癌症在内的各个领域的一个重大问题。相比之下，UAB CCC 已经开发了广泛的基础设施和必要的科学家数量。为了持续的尽管如此，亚利桑那州立大学的文化敏感性和视角可能是 UAB CCC 所缺乏的，因此，合作伙伴将促进癌症相关研究、培训（职业发展）和教育方面的合作，以帮助这个服务不足的社区。教师/科学家将与亚利桑那州立大学的教师和学生合作，启动癌症研究项目，为亚利桑那州立大学的教师和学生开展癌症研究项目创造一个渠道。拟议的努力将通过提供前列腺癌和结直肠癌（两者）的先进研究来吸引服务不足的群体。其中包括非裔美国人的主要癌症健康差异），通过向学生和教师提供培训，并将与癌症健康差异相关的主题引入亚利桑那州立大学的本科生和研究生课程。拟议的合作伙伴关系有一个行政核心，即癌症研究计划。该伙伴关系将由一个内部咨询委员会指导，该委员会由两个职能项目和一个癌症培训和教育计划组成。每个机构的杰出科学家；由两个机构的成员组成的执行委员会；以及每个组织的癌症培训和教育计划将覆盖亚利桑那州立大学的优秀学生和教师，将他们与现有的研究人员和研究联系起来。 UAB CCC 的基础设施，并促进癌症研究领域的教师、研究生和本科生以及教育，以增加参与癌症研究的少数族裔研究人员的数量。生物伦理学支持的目标是提供卓越的服务。整个生命伦理学教育、培训、指导和咨询生物统计学/生物信息学支持的目标是满足该伙伴关系资助的研究项目的统计/生物信息学需求。该伙伴关系的具体目标是：(1) 通过发展初级教职人员，增强统计/生物信息学的能力。研究和行政基础设施，以在亚利桑那州立大学开展竞争性基础和社区癌症研究；(2) 培养致力于在两个合作机构研究癌症差异的研究人员；(3) 建立少数族裔癌症差异研究人员和卫生专业人员的渠道；亚利桑那州立大学和阿拉巴马大学之间。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Tracing the dynamics of gene transcripts after organismal death.

DOI：
10.1098/rsob.160267
发表时间：
2017-01
期刊：
Open biology
影响因子：
5.8
作者：
Pozhitkov AE;Neme R;Domazet-Lošo T;Leroux BG;Soni S;Tautz D;Noble PA
通讯作者：
Noble PA

Optimum health and inhibition of cancer progression by microbiome and resveratrol.

DOI：
10.2741/4904
发表时间：
2021-01-01
期刊：
Frontiers in bioscience (Landmark edition)
影响因子：
0
作者：
Stokes Iii J;Vinayak S;Williams J;Malik S;Singh R;Manne U;Owonikoko TK;Mishra MK
通讯作者：
Mishra MK

Targeting Hsp70: A possible therapy for cancer.