Alcohol Intoxication as a Risk Factor for Intimate Partner Aggression among Adults with ADHD

酒精中毒是成年多动症患者亲密伴侣攻击行为的一个危险因素

• 批准号: 9316220
• 负责人: BRIAN T WYMBS
• 金额: $ 21.63万
• 依托单位: OHIO UNIVERSITY ATHENS
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-20 至 2019-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9316220
• 关键词: Acute; Address; Adult; Adverse effects; Aggressive behavior; Alcohol abuse; Alcohol consumption; Alcoholic Beverages; Alcoholic Intoxication; Alcohols; Attention; Attention deficit hyperactivity disorder; Behavior; Behavioral; Biological; Caregivers; Child; Child Abuse and Neglect; Childhood; Couples; Cues; Diagnosis; Economics; Emotional; Environment; Event; Exanthema; Executive Dysfunction; Expectancy; Exposure to; Gender; Goals; Heterosexuals; Hormonal; Hydrocortisone; Individual; Intervention; Investigation; Knowledge; Laboratories; Link; Measures; Medical; Mental Depression; Mental Health; Mental disorders; Neurologic; Participant; Population; Populations at Risk; Prevention program; Process; Public Health; Randomized; Reaction; Recruitment Activity; Regulation; Research; Research Personnel; Risk; Risk Factors; Sampling; Severities; Symptoms; Testing; Testosterone; Victimization; Violence; Woman; Work; aged; alcohol consequences; alcohol effect; alcohol risk; base; chronic pain; clinically relevant; cost; drinking; executive function; experience; intervention program; intimate partner violence; male; men; negative mood; neglect; non-alcoholic; partner aggression; perpetrators; response; screening; sobriety; theories; therapy design; trait; young adult

Project Summary: The primary aims of this study are to: (1) Evaluate whether risk of perpetrating intimate partner aggression (IPA) when intoxicated is greater among young adults (aged 21 to 35 years) with attention-deficit hyperactivity disorder (ADHD) than young adults without ADHD, and (2) Investigate whether certain biological, neurological, and dispositional risk factors that may strengthen the risk of adults with ADHD perpetrating IPA when intoxicated. The long-term goal of this research is to evaluate whether alcohol consumption is a more potent risk factor for IPV in young adults with than without ADHD and, if so, to reduce their risk of IPA perpetration by including interventions to reduce their risk in existing treatments for ADHD. Young adults with ADHD are at-risk for IPV perpetration, and preliminary evidence indicates that problematic alcohol use is more likely to predict IPA among young adults with ADHD than those without ADHD. However, it remains unclear whether young adults with ADHD are more likely to perpetrate IPA when under the influence of alcohol and when provoked. Furthermore, investigations are needed to test whether specific biological (e.g., testosterone:cortisol ratio), neurological (e.g., behavioral inhibitory control), and dispositional risk factors (e.g., alcohol-aggression expectancies) identify adults with ADHD at increased risk of perpetrating IPA when intoxicated and provoked. To address these gaps in our knowledge, 66 heterosexual couples including young adults with ADHD and 34 heterosexual couples including young adults without ADHD will be recruited to participate in an alcohol administration study. Participants will be randomly assigned to either receive an alcoholic beverage or to receive a non-alcoholic beverage, and afterwards their level of partner-directed aggression in response to provocation will be unobtrusively measured via laboratory-based aggression task. We hypothesize that intoxicated adults with ADHD will perpetrate more severe IPA when provoked than sober adults with ADHD or adults without ADHD, regardless of being intoxicated or sober. Among adults with ADHD, we also hypothesize that individuals who are intoxicated and have specific biological, neurological, and/or dispositional traits will perpetrate more severe alcohol-facilitated IPA when provoked than intoxicated adults with ADHD but without the same traits, or adults with ADHD who are sober, regardless of their biological, neurological or dispositional traits. Finally, we hypothesize that adults with ADHD who have multiple risk factors will be at greatest risk of IPA perpetration when intoxicated.

项目摘要： 这项研究的主要目的是：（1）评估是否存在亲密伴侣侵略的风险 （IPA）当醉酒的年轻人（21至35岁）中醉酒较大时，注意力缺陷多动症 疾病（ADHD）比没有多动症的年轻人，以及（2）研究某些生物学，神经系统是否存在 以及可能会加强成年人患有多动症IPA的成年人风险的处置风险因素 酣。这项研究的长期目标是评估饮酒是否更有效 与没有多动症的年轻人相比，IPV的危险因素，如果是的，则可以通过 包括干预措施以降低其在ADHD现有治疗中的风险。患有多动症的年轻人处于危险中 对于IPV进行犯罪，初步证据表明，饮酒有问题更有可能预测 患有多动症的年轻人中的IPA比没有多动症的IPA。但是，尚不清楚年轻 在酒精的影响下，患有多动症的成年人更有可能进行IPA。 此外，还需要进行研究来测试特定的生物学（例如睾丸激素：皮质醇比）， 神经学（例如行为抑制性控制）和处置风险因素（例如，酒精侵略性 预期）确定患有多动症的成年人在醉酒和挑衅时会增加IPA的风险。 为了解决我们所知的这些差距，包括多动症的年轻人在内的66对异性恋夫妇和34 包括没有多动症的年轻人在内的异性恋夫妇将被招募参加酒精 行政研究。参与者将被随机分配给接受酒精饮料或 获得非酒精饮料，之后是他们的合作伙伴指导侵略水平 挑衅将通过基于实验室的侵略任务来毫不客气地衡量。我们假设这一点 与患有多动症或多动症的成年人相比 没有多动症的成年人，无论陶醉或清醒。在患有多动症的成年人中，我们还假设 陶醉并具有特定生物学，神经和/或性格性状的人将 当引起多动症的成年人引起时，持续性饮酒时更严重的IPA，但没有 无论其生物学，神经或性格如何 特质。最后，我们假设患有多个危险因素的ADHD成年人将是最大的风险 陶醉时IPA进行。