Training Program in the Pathophysiology of Renal Disease

肾脏疾病病理生理学培训计划

基本信息

批准号：
9094723
负责人：
JOHN M. ARTHUR
金额：
$ 13.62万
依托单位：
UNIV OF ARKANSAS FOR MED SCIS
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
起止时间：
2006-09-01 至 2017-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9094723
关键词：
Functional disorder Kidney Diseases Training Programs

项目摘要

DESCRIPTION (provided by applicant): Continuation of an institutional Training Program in the Pathophysiology of Renal Diseases is proposed for postdoctoral MDs recruited after internal medicine residency program or PhDs. The goals of this training program are to train physicians and PhD scientists in four areas of renal research including i) acute kidney injury, ii) cardiovascular risk of chronic kidney disease, iii) basic science aspects of renal transplantation and iv) new therapies for diabetic nephropathy. These areas will provide comprehensive training in basic and clinical translational research. The training program will require a commitment of two years of research funded by the T32 grant followed by one year of clinical training for MDs. During the first year the trainees will have the option to enroll in coursework to earn a Certificae in Clinical and Translational Sciences through the Interdisciplinary Biomedical Sciences (IBS) Graduate Program. The program faculty represents a closely-knit, interactive, multidisciplinary faculty from the Division of Nephrology and Departments of Pharmacology and Toxicology, Microbiology and Immunology, Biochemistry and Molecular Biology, Geriatrics, and Physiology and Biophysics including 9 MDs, 3 MD PhDs, 11 PhDs, and 1 MD MPH. Trainees are expected to master at least one major investigative technique, complete at least one major research project, present their work at a national meeting and apply for NIH funding (K08 award) at the end of their research training. Fellows completing this program will be competitive candidates for academic research careers.

描述（由申请人提供）：在内部医学驻留计划或博士学位后招募了肾脏疾病病理生理学的机构培训计划。该培训计划的目标是在肾脏研究的四个领域中培训医生和博士学位科学家，包括i）急性肾脏损伤，ii）慢性肾脏病的心血管风险，ii）肾移植和iv的基础科学方面，iv）糖尿病性肾病的新疗法。这些领域将提供基础和临床翻译研究的全面培训。该培训计划将需要由T32赠款资助的两年研究的承诺，然后对MDS进行一年的临床培训。在第一年，学员将可以选择参加课程工作，以通过跨学科生物医学科学（IBS）研究生课程获得临床和转化科学证书。该计划的教职员工代表了药理学和毒理学，毒理学，微生物学和免疫学，生物化学和分子生物学，老年生理学，以及生理和生物物理学，包括9 MDS，3 MD PHDS，11 MD PHDS，11 PHDS，11 PHDS和1 MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MD MDM，预计受训人员将掌握至少一项主要的调查技术，完成至少一项重大研究项目，在全国会议上介绍他们的工作，并在研究培训结束时申请NIH资金（K08奖）。完成该计划的研究员将成为学术研究职业的竞争候选人。

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Metal deposition in calcific uremic arteriolopathy.

DOI：
10.1016/j.jaad.2009.01.042
发表时间：
2009-07
期刊：
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
影响因子：
13.8
作者：
Amuluru, Lavanya;High, Whitney;Hiatt, Kim M.;Ranville, James;Shah, Sudhir V.;Malik, Bilal;Swaminathan, Sundararaman
通讯作者：
Swaminathan, Sundararaman

Renal Mitochondrial Lipid Peroxidation during Sepsis.

脓毒症期间的肾线粒体脂质过氧化。

DOI：
10.4172/jok.1000116
发表时间：
2016
期刊：
Journal of kidney
影响因子：
0
作者：
Singh,P;Parajuli,N;Mayeux,PR;MacMillan-Crow,LA
通讯作者：
MacMillan-Crow,LA

Role of reduced manganese superoxide dismutase in ischemia-reperfusion injury: a possible trigger for autophagy and mitochondrial biogenesis?

DOI：
10.1152/ajprenal.00435.2012
发表时间：
2013-02-01
期刊：
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
影响因子：
4.2
作者：
Parajuli, Nirmala;MacMillan-Crow, Lee Ann
通讯作者：
MacMillan-Crow, Lee Ann

Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury.

DOI：
10.1371/journal.pone.0140025
发表时间：
2015
期刊：
PloS one
影响因子：
3.7
作者：
Chandrika BB;Yang C;Ou Y;Feng X;Muhoza D;Holmes AF;Theus S;Deshmukh S;Haun RS;Kaushal GP
通讯作者：
Kaushal GP

Cold Storage Exacerbates Renal and Mitochondrial Dysfunction Following Transplantation.

冷藏会加剧移植后的肾脏和线粒体功能障碍。