Nebraska Center for Cellular Signaling

内布拉斯加州细胞信号中心

基本信息

批准号：
9324327
负责人：
KEITH R JOHNSON
金额：
$ 94.39万
依托单位：
UNIVERSITY OF NEBRASKA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-09-05 至 2019-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9324327
关键词：
Academia Administrative Supplement Appointment Area Award Basic Science Budgets Centers of Research Excellence Cessation of life Communities Country Dentistry Development Environment Equipment Faculty Faculty Recruitment Financial compensation Funding Future Germination Goals Grant Health Human Individual Institutes Institution Japan Knowledge Laboratories Leadership Left Malignant Neoplasms Manuscripts Measures Medical center Medicine Mentors Microscope Mission Nebraska Outcome Phase Pilot Projects Positioning Attribute Postdoctoral Fellow Principal Investigator Process Program Development Publications Recording of previous events Research Research Infrastructure Research Personnel Running Scientist Senior Scientist Services Signal Transduction Site Visit Talents Time Travel United States United States National Institutes of Health Universities Wages Work career development collaborative environment college cost design editorial graduate student higher education innovation live cell imaging meetings member professor programs public health relevance success symposium tumorigenesis

项目摘要

DESCRIPTION (provided by applicant): This COBRE Phase III application proposes to continue The Nebraska Center for Cellular Signaling which was established to strengthen research within the University of Nebraska Medical Center (UNMC). The Specific Aims of this application are: Aim 1: Provide support to sustain collaborative research and mentoring of new investigators in the realm of cellular signaling. Aim 2: Strengthen research capabilities, innovation, and funding support for investigators affiliated with the NCCS. Aim 3: Graduate the NCCS from IDeA funding as a self-sustaining center of research excellence in cellular signaling. The Center was established with Phase I and II funding from the COBRE program. The stated objectives of the Center were 1) to expand the current focus on cellular signaling; 2) to increase the research profile of research universities in Nebraska, especially the College of Dentistry of UNMC, and 3) to contribute to the development of promising young faculty, so that they will become prominent members of the scientific community as evidenced by significant NIH funding, publication of important manuscripts, service on review panels and invitations to speak across the country. We have accomplished each of our goals with exceptional success. With our infrastructure in place, nine beginning Assistant Professors received ROI or major ACS support. Three of the four new faculty recruited to the College of Dentistry are among these nine. We have instituted programs designed to enhance and sustain the Center, including support for collaborative projects, ongoing seminar programs, and utilization of cores and a professional development team. The success of our career development programs is shown by appointments of our graduates to editorial boards, service on review panels as members or chairs, and invitations to present seminars. We have strong support from the institution with plans in place to sustain the Center when COBRE funding expires. The PI and co-directors are committed to continuing our culture of mentoring and our culture of success. The collaborative environment resulting from the formation of the Center has and will continue to enhance research and the research infrastructure within Nebraska's research institutions.

描述（由申请人提供）：本 COBRE III 期申请建议继续建立内布拉斯加州细胞信号传导中心，该中心的成立是为了加强内布拉斯加州大学医学中心 (UNMC) 内的研究。该申请的具体目标是：目标 1：为维持细胞信号传导领域的新研究人员的合作研究和指导提供支持。目标 2：加强对 NCCS 附属研究人员的研究能力、创新和资金支持。目标 3：将 NCCS 从 IDeA 资助中毕业，成为细胞信号传导领域自我维持的卓越研究中心。该中心是在 COBRE 计划第一期和第二期资金的支持下成立的。该中心的既定目标是 1) 扩大当前对细胞信号传导的关注； 2) 提高内布拉斯加州研究型大学的研究形象，特别是 UNMC 牙科学院，以及 3) 为有前途的年轻教师的发展做出贡献，使他们成为科学界的杰出成员，正如 NIH 所证明的那样资金、重要手稿的出版、评审小组的服务以及在全国各地演讲的邀请。我们以非凡的成功实现了我们的每一个目标。随着我们的基础设施到位，九名新任助理教授获得了 ROI 或主要 ACS 支持。牙科学院新聘的四名教员中的三名就在这九人之中。我们制定了旨在加强和维持该中心的计划，包括支持合作项目、正在进行的研讨会计划以及利用核心和专业开发团队。我们的职业发展计划的成功体现在我们的毕业生被任命为编辑委员会、担任审查小组成员或主席以及受邀参加研讨会。我们得到了该机构的大力支持，并制定了在 COBRE 资金到期后维持该中心的计划。 PI 和联合董事致力于延续我们的指导文化和成功文化。该中心的成立所产生的协作环境已经并将继续加强内布拉斯加州研究机构内的研究和研究基础设施。

项目成果

期刊论文数量（15）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Lack of an apparent role for endothelin-1 in the prolonged reduction in renal perfusion following severe unilateral ischemia-reperfusion injury in the mouse.

DOI：
10.14814/phy2.13027
发表时间：
2016-11
期刊：
Physiological reports
影响因子：
2.5
作者：
Boesen EI
通讯作者：
Boesen EI

Outside the mainstream: novel collecting duct proteins regulating water balance.

DOI：
10.1152/ajprenal.00488.2016
发表时间：
2016-12
期刊：
American journal of physiology. Renal physiology
影响因子：
0
作者：
S. Rahman;Erika I Boesen
通讯作者：
S. Rahman;Erika I Boesen

Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma Treatment.

DOI：
10.3390/diagnostics12010061
发表时间：
2021-12-28
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
0
作者：
Ray S;Chaturvedi NK;Bhakat KK;Rizzino A;Mahapatra S
通讯作者：
Mahapatra S

Traumatic brain injury increases levels of miR-21 in extracellular vesicles: implications for neuroinflammation.

DOI：
10.1002/2211-5463.12092
发表时间：
2016-08
期刊：
FEBS open bio
影响因子：
2.6
作者：
Harrison EB;Hochfelder CG;Lamberty BG;Meays BM;Morsey BM;Kelso ML;Fox HS;Yelamanchili SV
通讯作者：
Yelamanchili SV

Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.