Relationship of Loss of Control Eating to Excessive Gestational Weight Gain

饮食失控与妊娠期体重过度增加的关系

基本信息

批准号：
9026631
负责人：
MICHELE D LEVINE
金额：
$ 39.28万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-03-01 至 2018-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9026631
关键词：
Affect Behavior Behavioral Behavioral Mechanisms Binge Eating Child Clinic Clinical Coupled DSM-IV Data Development Diagnosis Discipline of obstetrics Distress Eating Eating Disorders First Pregnancy Trimester Food Frequencies Goals Guidelines Health Hospitals Hyperphagia Ingestion Institute of Medicine (U.S.)Intake Intervention Interview Lead Measures Medical Mothers Obesity Outcome Overweight Persons Physical activity Postpartum Period Pregnancy Pregnancy Outcome Pregnant Women Psychological Factors Psychopathology Psychosocial Factor Recruitment Activity Research Risk Social support Stress Structure Telephone Visit Weight Weight Gain Weight maintenance regimen Woman Women&apos s Health Work abstracting depressive symptoms effective intervention experience gestational weight gain improved loss of control over eating obesity risk obesity treatment offspring prevent psychosocial

项目摘要

DESCRIPTION (provided by applicant): More than 45% of women exceed guidelines established by the Institute of Medicine (IOM) for gestational weight gain (GWG). Women who begin pregnancy overweight or obese are more likely to exceed the IOM guidelines than are normal weight women. Excessive (GWG) is associated with negative obstetric outcomes, increases the risk of obesity in offspring and leads to greater postpartum weight retention. Preventing excessive GWG can improve obstetric outcomes and may lead to improvements in the treatment of obesity for women. However, interventions to prevent excessive GWG have not been consistently successful, and there is a need to identify modifiable behaviors related to GWG to support the development of effective interventions to prevent excessive GWG. Loss of control over eating (LOC), or the ingestion of food coupled with a sense of being unable to control the quantity eaten, is strongly associated with weight gain and is modifiable. LOC also is related to depressive symptoms and psychosocial distress which also are associated with weight gain. Thus, the goal of the proposed study is to assess relationships among GWG, LOC and psychosocial distress. Pregnant women (N = 300) who are overweight or obese prior to pregnancy (i.e., pregravid BMI>25) will be recruited from obstetric clinics at a local women's hospital. Women will complete structured, clinical interviews including the Eating Disorder Examination (EDE) and the Structured Clinical Interview for DSM- IV diagnoses (SCID) to document LOC and depressive symptoms at the end of the first trimester of pregnancy. Measures of perceived stress, social support, calorie intake, physical activity, and other factors related to GWG also will collected in first trimester. Assessments of LOC, psychosocial distress, eating and activity will be repeated monthly by telephone between weeks 20 and 36 of pregnancy. To document postpartum weight retention, women will be interviewed again at 6 months postpartum. Weight will be assessed at each in person visit and GWG abstracted from women's medical charts at the end of pregnancy. The proposed research is an extension of previous work conducted by the investigative team, and will provide important data on modifiable mechanisms for excessive GWG. Understanding behavioral mechanisms of excessive GWG is likely to inform interventions to prevent excessive GWG and thereby improve the health of mothers and children.

描述（由申请人提供）：超过 45% 的女性超过医学研究所 (IOM) 制定的妊娠期体重增加 (GWG) 指南。怀孕开始时超重或肥胖的女性比体重正常的女性更有可能超出国际移民组织 (IOM) 的指导方针。过量 (GWG) 与不良产科结果相关，增加后代肥胖的风险，并导致产后体重滞留更大。防止 GWG 过多可以改善产科结果，并可能改善女性肥胖的治疗。然而，防止 GWG 过多的干预措施并未始终取得成功，因此需要确定与 GWG 相关的可修改行为，以支持制定有效的干预措施来防止 GWG 过多。饮食失控（LOC），即摄入食物并伴有无法控制进食量的感觉，与体重增加密切相关，并且是可以改变的。 LOC 还与抑郁症状和社会心理困扰有关，这些症状也与体重增加有关。因此，本研究的目的是评估 GWG、LOC 和社会心理困扰之间的关系。将从当地妇女医院的产科诊所招募怀孕前超重或肥胖（即孕前BMI>25）的孕妇（N = 300）。女性将完成结构化的临床访谈，包括饮食失调检查 (EDE) 和 DSM-IV 诊断的结构化临床访谈 (SCID)，以记录妊娠前三个月末的 LOC 和抑郁症状。感知压力、社会支持、卡路里摄入量、体力活动以及其他与 GWG 相关的因素的测量也将在妊娠早期收集。在怀孕第 20 周至第 36 周期间，将每月通过电话重复评估 LOC、社会心理困扰、饮食和活动。为了记录产后体重保留情况，女性将在产后 6 个月再次接受采访。每次亲自就诊时都会评估体重，并在怀孕结束时从女性病历中提取 GWG。拟议的研究是调查小组之前所做工作的延伸，并将提供关于过量 GWG 的可修改机制的重要数据。了解 GWG 过多的行为机制可能会为预防 GWG 过多的干预措施提供信息，从而改善母亲和儿童的健康。