12th and 13th International Symposia on Neurobiology and Neuroendocrinology of Ag

第12届和第13届银神经生物学和神经内分泌学国际研讨会

基本信息

批准号：
9058973
负责人：
HOLLY M. BROWN-BORG
金额：
$ 2.96万
依托单位：
UNIVERSITY OF NORTH DAKOTA
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-05-01 至 2017-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9058973
关键词：
Address Aging Alzheimer&apos s Disease Area Austria Biology of Aging Cell Aging Cell Therapy Clinical Collaborations Communication Comorbidity DNA Damage Disease Environment Epigenetic Process Faculty Funding Geriatrics Gerontology HIV Health Hormonal Insulin-Like Growth Factor I International Left Leptin Longevity Mitochondria Modeling Molecular Biology Myocardium Nerve Degeneration Neuraxis Neurobiology Neurocognitive Deficit Neurodegenerative Disorders Neuroendocrinology Neurons Oral Participant Positioning Attribute Postdoctoral Fellow Publishing Request for Applications Request for Proposals Research Research Personnel Role Science Scientist Senior Scientist Skin Slide System Technology Time Training Translations United States abstracting age related body system graduate student humanized mouse immunosenescence interest lectures meetings neuroprotection novel posters student conference symposium

项目摘要

DESCRIPTION (provided by applicant): The Twelfth and Thirteenth International Symposia on Neurobiology and Neuroendocrinology Aging will be held in Bregenz, Austria July 27-August 1, 2014 and in July 2016. The purpose of these meetings is to bring together a group of investigators who made recent significant advances in the study of mechanisms of aging, with particular emphasis on CNS aging, neuroprotection and treatment of neurodegenerative disease. Specific topics will include the diverse roles of IGF-1 in health span and lifespan and the interplay of IGF-1 and leptin in neuroprotection. Several lectures focus on diverse aspects of neurodegeneration including cell- based therapies, the environment and epigenetics, DNA damage, and mitochondrial sensitivity plus one that merges multiple models to understand neurodegeneration. Four lectures will specifically address recent advances in cellular senescence and age-related disease. An exciting new area of aging will be the focus of a group of presentations on HIV. These talks will focus on HIV and neurocognitive impairment, comorbidities, immunosenescence and the humanized mouse system. Discussion of mechanisms specifically related to aging of organ systems (heart, muscle, skin) will occupy another set of lectures. We purposely include a wide range of topics and assemble a group of scientists that may not normally attend the same meeting. The format of the meeting is modeled after Gordon Research Conferences and encourages formal and informal discussions of the material presented. Proceedings will be published as a special issue of Experimental Gerontology as has been done for the last 11 Symposia. Participation of junior investigators, including graduate students and post-doctoral fellows is strongly encouraged and this proposal seeks funds for providing stipends to those US participants who are in training or are in junior faculty positions and who are planning to present their findings in the poster session. We are also seeking partial support for the expenses of invited speakers from the United States.

描述（由申请人提供）：第十二和第十三国际神经生物学和神经内分泌学衰老介绍将在奥地利的布雷氏邦举行神经退行性疾病。具体主题将包括IGF-1在健康跨度和寿命中的各种作用，以及IGF-1和瘦素在神经保护中的相互作用。几个讲座的重点是神经变性的各个方面，包括基于细胞的疗法，环境和表观遗传学，DNA损伤和线粒体敏感性以及合并多个模型以了解神经变性的敏感性。四个讲座将特别解决细胞衰老和与年龄有关的疾病的最新进展。令人兴奋的新衰老领域将是一组关于艾滋病毒的演讲的重点。这些谈判将集中于HIV和神经认知障碍，合并症，免疫衰老和人源化小鼠系统。讨论与器官系统（心脏，肌肉，皮肤）特别相关的机制将占据另一套讲座。我们故意包含各种各样的主题，并组装一群通常不会参加同一会议的科学家。会议的格式以戈登研究会议为基础，并鼓励对所介绍的材料进行正式和非正式的讨论。会议记录将作为实验老年病的特刊，就像过去11场研讨会所做的那样。强烈鼓励初级调查人员的参与，包括研究生和博士后研究员，该建议寻求资金为那些正在培训或从事初级教师职位的美国参与者提供津贴，并计划在海报会议上介绍他们的发现。我们还为美国受邀发言人的费用寻求部分支持。