Neuropathology & Targeted Molecular Testing Core

神经病理学

• 批准号: 9088283
• 负责人: CHRISTOPHER DIRK KEENE
• 金额: $ 40.02万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9088283
• 关键词: Abbreviations; Adult; Aging; Alzheimer' s Disease; Autopsy; Award; Biological; Biological Assay; Biological Markers; Body Fluids; Brain; Brain region; Cells; Cerebrospinal Fluid; Cerebrovascular Trauma; Clinical; Clinical Data; Clinical Research; Clinical Trials; Consensus; Data; Data Quality; Dementia; Development; Diagnostic; Disease; Education; Educational process of instructing; Ensure; Environment; Enzyme-Linked Immunosorbent Assay; Evaluation; Faculty; Formalin; Fostering; Frontotemporal Dementia; Future; Genetic Markers; Genetic screening method; Glass; Guidelines; Health; Histology; Immunohistochemistry; Impaired cognition; Individual; Interdisciplinary Study; International; Late Onset Alzheimer Disease; Leadership; Lewy Body Disease; Liquid substance; Longitudinal Studies; Medical Students; Methods; Mission; Molecular; Molecular Target; Nerve Degeneration; Neurodegenerative Disorders; Pacific Northwest; Paraffin Embedding; Pathologic; Pathologic Processes; Patients; Physicians; Positioning Attribute; Process; Productivity; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Resources; Scientist; Slide; Specimen; Staging; Structure; Techniques; Testing; Tissues; Training; Translational Research; Universities; Vision; aging brain; biobank; brain research; brain tissue; data management; forest; graduate student; innovation; molecular pathology; neuropathology; outreach; precision medicine; repository; research study; statistics; targeted biomarker

CORE D: NPTMT ABSTRACT The Neuropathology and Targeted Molecular Testing (NPTMT) Core has been a valuable and frequently utilized resource for UW ADRC as it pursues its vision of precision medicine for Alzheimer's disease (AD) as well as for local and national AD research. The mission and thus, specific aims, have not significantly changed from the current award: (i) provide diagnostic expertise, (ii) provide targeted biomarker and genetic testing, (iii) build a highly accessible repository of brain tissue and fluid, (iv) develop innovative approaches, and (v) maintain a rich training environment. All of our research activities are focused on enhancing the research value of tissue and body fluid donations from cognitively healthy individuals and those in the early stages of AD while ensuring proper safeguards.

核心 D：NPTMT 摘要 神经病理学和靶向分子检测 (NPTMT) 核心一直是一个有价值且频繁的研究 利用 UW ADRC 的资源来实现阿尔茨海默病 (AD) 精准医疗的愿景 以及地方和国家 AD 研究。使命以及具体目标没有发生重大变化 从目前的奖项来看：(i) 提供诊断专业知识，(ii) 提供有针对性的生物标志物和基因检测，(iii) 建立一个高度可访问的脑组织和液体储存库，（iv）开发创新方法，以及（v） 保持丰富的培训环境。我们所有的研究活动都致力于提高研究价值 来自认知健康个体和 AD 早期阶段个体的组织和体液捐赠，同时 确保适当的保障措施。