Development and Evaluation of a Preventive Intervention for Children with FASD

胎儿酒精谱系谱系障碍 (FASD) 儿童预防性干预措施的制定和评估

• 批准号: 8485465
• 负责人: CHRISTIE Lynn McGee Petrenko
• 金额: $ 11.35万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-20 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8485465
• 关键词: Adolescence; Adult; Advocacy; Affect; Alcohol or Other Drugs use; Area; Attention; Behavior; Caregivers; Child; Communities; Competence; Development; Development Plans; Educational Curriculum; Educational Intervention; Emotional; Ensure; Etiology; Evaluation; Faculty; Family; Feasibility Studies; Feedback; Fetal Alcohol Exposure; Fetal Alcohol Spectrum Disorder; Fetal Alcohol Syndrome; Focus Groups; Fostering; Foundations; Goals; Home environment; Individual; Intervention; Intervention Studies; K-Series Research Career Programs; Knowledge; Laws; Mental Health; Mentors; Methodology; Methods; Outcome; Parenting behavior; Participant; Pathway interactions; Population; Prevention; Preventive Intervention; Probability; Problem behavior; Psychopathology; Public Health; Quality of life; Randomized Controlled Trials; Recording of previous events; Research; Research Personnel; Resources; Risk; Risk Factors; Schools; Science; Severities; Sex Behavior; Social Welfare; Societies; Solutions; Stress; Substance abuse problem; Testing; Training; Training Activity; Universities; Work; adverse outcome; alcohol exposure; burden of illness; career development; clinically significant; cost; cost effective; design; efficacy testing; efficacy trial; executive function; experience; follow-up; implementation trial; improved; information processing; interest; life time cost; multidisciplinary; post intervention; prevent; programs; service utilization; skills; social skills; theories; therapy design

DESCRIPTION (provided by applicant): Dr. Christie McGee Petrenko will be joining the faculty of the Mt. Hope Family Center at the University of Rochester in July 2011. Her long-term goal is to establish a productive program of research focusing on the prevention of adverse outcomes (e.g., mental health problems, trouble with the law, substance use) in children with prenatal alcohol exposure. As outlined in her Career Development Plan, a multidisciplinary team of experts will provide her with advanced training and mentoring in several areas, including: prevention science, developmental psychopathology, intervention design and implementation, randomized controlled trials, and longitudinal methodology. Advanced training in these areas will serve as an excellent foundation for Dr. Petrenko to continue her program of research and foster her development as an independent researcher. The proposed research will incorporate multiple methods to rigorously develop and evaluate a preventive intervention for children with prenatal alcohol exposure (grades K-2). The preliminary framework of the proposed intervention includes concurrent child and caregiver skills groups and individualized family advocacy. The intervention will target multiple short- and long-term outcomes, including mental health, school adjustment, social competence, delinquency, parenting, and home environment. Pre-intervention research will inform the content and framework of the preventive intervention. Specifically, focus groups will be conducted with key community stakeholders (caregivers and helping professionals) to evaluate perceived needs and the acceptability of the proposed intervention. Once a tailored intervention is developed, an implementation trial will be conducted to fine-tune the curriculum and ensure the preventive intervention is feasible and engaging for families. The intervention will then be piloted and evaluated through a randomized controlled trial. The proposed preventive intervention aims to improve competence and reduce risk factors for children with prenatal alcohol exposure and increase the likelihood that they will continue on an adaptive developmental trajectory. This intervention has the potential to improve the quality of life for children with FASD and their families and reduce the significant costs to society that accompany prenatal alcohol exposure. This research will also be applied more broadly to test current theories of developmental psychopathology and prevention science, which will improve our understanding of the etiology and malleability of maladaptive behaviors.

描述（由申请人提供）：Christie McGee Petrenko 博士将于 2011 年 7 月加入罗切斯特大学霍普山家庭中心 (Mt. Hope Family Center) 任教。她的长期目标是建立一个富有成效的研究计划，重点关注预防产前酒精暴露儿童的不良后果（例如，心理健康问题、触犯法律、药物滥用）。正如她的职业发展计划所述，多学科专家团队将为她提供多个领域的高级培训和指导，包括：预防科学、发展精神病理学、干预设计和实施、随机对照试验和纵向方法。这些领域的高级培训将为 Petrenko 博士继续她的研究计划并促进她作为独立研究员的发展奠定良好的基础。拟议的研究将采用多种方法来严格制定和评估针对产前酒精暴露儿童（K-2 级）的预防干预措施。拟议干预措施的初步框架包括同时开展的儿童和看护者技能小组以及个性化家庭宣传。干预措施将针对多种短期和长期结果，包括心理健康、学校适应、社交能力、犯罪、养育和家庭环境。干预前研究将为预防干预的内容和框架提供信息。具体而言，将与主要社区利益相关者（护理人员和帮助专业人员）进行焦点小组讨论，以评估感知的需求和拟议干预措施的可接受性。一旦制定了量身定制的干预措施，将进行实施试验，以微调课程并确保预防性干预措施可行且对家庭有吸引力。然后将通过随机对照试验对干预措施进行试点和评估。拟议的预防干预措施旨在提高产前酒精暴露儿童的能力并减少危险因素，并增加他们继续沿着适应性发展轨迹的可能性。这种干预措施有可能改善 FASD 儿童及其家人的生活质量，并减少产前酒精暴露给社会带来的重大成本。这项研究还将更广泛地应用于测试当前的发展精神病理学和预防科学理论，这将提高我们对适应不良行为的病因学和可塑性的理解。