Hexokinase 2 in liver cancer

己糖激酶 2 在肝癌中的作用

• 批准号: 9195585
• 负责人: Nissim Hay
• 金额: $ 39.82万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9195585
• 关键词: Ablation; Address; Adult; Affinity; Applications Grants; Binding; Carcinoma; Cell Death; Cell Line; Cell Proliferation; Cell Survival; Cells; Development; Dose; Drug Delivery Systems; Dysplasia; Embryo; Enzymes; Event; Genes; Genetic Heterogeneity; Glucokinase; Glucose-6-Phosphate; Glycolysis; Goals; Hepatic; Hepatocarcinogenesis; Hepatocyte; Hexokinase 2; Human; In Vitro; Intervention; Liver; Maintenance; Malignant Epithelial Cell; Malignant Neoplasms; Malignant neoplasm of liver; Malignant neoplasm of lung; Metabolism; Metformin; Mitochondria; Mus; Oxygen Consumption; Patients; Peptides; Pharmacotherapy; Physiological; Predisposition; Primary carcinoma of the liver cells; Prodrugs; Protein Isoforms; Proteins; Sampling; Signal Transduction; Surveys; Therapeutic; Therapeutic Agents; Tumorigenicity; Xenograft procedure; analog; cancer cell; glucose metabolism; hepatocellular carcinoma cell line; hexokinase; in vivo; inhibitor/antagonist; knock-down; liver function; malignant breast neoplasm; mouse model; novel; tumor; tumorigenesis